Unlocking the therapeutic potential of selective CDK7 and BRD4 Inhibition against multiple myeloma cell growth
Yao, Yao, Deng, Shuhui, Ng, Jessica Fong, Yuan, Mei, Chakraborty, Chandraditya, JoyWeiler, Vera, Munshi, Nikhil, Fulciniti, Mariateresa
Published in Haematologica (Roma) (25.07.2024)
Published in Haematologica (Roma) (25.07.2024)
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Journal Article
CDK7 controls E2F- and MYC-driven proliferative and metabolic vulnerabilities in multiple myeloma
Yao, Yao, Ng, Jessica Fong, Park, Woojun Daniel, Samur, Mehmet, Morelli, Eugenio, Encinas Mayoral, Jessica, Chyra, Zuzana, Xu, Yan, Derebail, Sanika, Epstein, Charles, Nabet, Behnam, Chesi, Marta, Gray, Nathanael S., Young, Richard A., Kwiatkowski, Nicholas, Mitsiades, Constantine, Anderson, Kenneth C., Lin, Charles Y., Munshi, Nikhil C., Fulciniti, Mariateresa
Published in Blood (08.06.2023)
Published in Blood (08.06.2023)
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Journal Article
Venetoclax resistance leads to broad resistance to standard-of-care anti-MM agents, but not to immunotherapies
Deng, Shuhui, Derebail, Sanika, Weiler, Vera Joy, Fong Ng, Jessica, Maroto-Martin, Elena, Chatterjee, Madhumouli, Giorgetti, Giulia, Chakraborty, Chandraditya, Kalhotra, Poonam, Du, Ting, Yao, Yao, Prabhala, Rao, Shammas, Masood, Gulla, Annamaria, Aktas Samur, Anil, Samur, Mehmet Kemal, Qiu, Lugui, Anderson, Kenneth C., Fulciniti, Mariateresa, Munshi, Nikhil C.
Published in Blood advances (13.08.2024)
Published in Blood advances (13.08.2024)
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Journal Article
Venetoclax Resistance Results in Broad Resistance to Majority of Anti-MM Agents Due to the Suppression of Apoptosis but Can be Overcome By BCMA-Targeted Immunotherapy
Fulciniti, Mariateresa, Deng, Shuhui, Dereibal, Sanika, Weiler, Vera Joy, Chatterjee, Madhumouli, Ng Fong, Jessica, Chakraborty, Chandraditya, Prabhala, Rao, Shammas, Masood A., Aktas-Samur, Anil, Samur, Mehmet K., Gulla, Annamaria, Anderson, Kenneth C., Munshi, Nikhil C
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Higher CD56 Expression on Multiple Myeloma Cells Increases CD38 Expression, Reduces Intracellular NAD+ Levels, and Enhances the Efficacy of Daratumumab-Based Treatment Strategies
Giorgetti, Giulia, Becherini, Pamela, Maroto-Martin, Elena, Fenoglio, Daniela, Soncini, Debora, Martinuzzi, Claudia, Bruzzone, Santina, Benzi, Andrea, Nahimana, Aimable, Uras, Chiara Rosa Maria, Schavgoulidze, Anaïs, Ng Fong, Jessica, Lemoli, Roberto M., Munshi, Nikhil C, Fulciniti, Mariateresa, Cea, Michele
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
P-191 Acquisition of venetoclax resistance is characterized by higher expression of anti-apoptotic regulators, less mitochondrial priming, and broader resistance to anti-MM agents
Fulciniti, Mariateresa, Ng, Jessica Fong, Weiler, Joy, Deng, Shuhui, Chakraborty, Chandraditya, Samur, Mehmet, Gulla, Annamaria, Anderson, Kenneth, Munshi, Nikhil
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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Journal Article
CDK7 Inhibition Targets Proliferative and Metabolic Oncogenic Vulnerabilities in Multiple Myeloma
Yao, Yao, Fong Ng, Jessica, Park, Woojun D, Samur, Mehmet K., Morelli, Eugenio, Kwiatkowski, Nicholas P, Encinas Mayoral, Jessica, Chyra, Zuzana, Xu, Yan, Nabet, Behnam, Chesi, Marta, Gray, Nathaniel, Young, Richard A., Anderson, Kenneth C., Lin, Charles Y, Munshi, Nikhil C, Fulciniti, Mariateresa
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
P-194 Non-coding RNA LINC01410 interacts with the minichromosome maintenance (MCM) complex and is a dependency in multiple myeloma
Gramegna, Doriana, Liu, Na, Maisano, Domenico, Ng, Jessica Fong, Schavgoulidze, Anais, Favasuli, Vanessa, Gao, Claire, Aktas-Samur, Anil, Novina, Carl, Gulla, Annamaria, Anderson, Kenneth, Wert-Lamas, Leon, Samur, Mehmet, Morelli, Eugenio, Fulciniti, Mariateresa, Munshi, Nikhil
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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Journal Article
P-362 ID2 acts as a novel tumor suppressor in MM by inhibition of TCF3 transcriptional activity
Perini, Tommaso, Yao, Yao, Ng, Jessica Fong, Deng, Shuhui, Schavgoulidze, Anais, Binder, Moritz, Young, Ryan, Knudson, Mei, Epstein, Charles, Gulla, Annamaria, Morelli, Eugenio, Szalat, Raphael, Samur, Mehmet, Anderson, Kenneth, Fulciniti, Mariateresa, Munshi, Nikhil
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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Journal Article
P-119: CDK7 is a proximal regulator of cellular functions impacting MYC-driven pathways and eliciting unique metabolic vulnerabilities in multiple myeloma
Yao, Yao, Ng, Jessica Fong, Park, Woojun Daniel, Samur, Mehmet, Mayoral, Jessica Encinas, Morelli, Eugenio, Chyra, Zuzana, Kwiatkowski, Nicholas, Xu, Yan, Nabet, Behnam, Chesi, Marta, Gray, Nathaniel, Young, Richard A., Anderson, Kenneth, Lin, Charles, Munshi, Nikhil, Fulciniti, Mariateresa
Published in Clinical lymphoma, myeloma and leukemia (01.08.2022)
Published in Clinical lymphoma, myeloma and leukemia (01.08.2022)
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Journal Article