Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells
Ji, Zhong-Sheng, Miranda, R Dennis, Newhouse, Yvonne M, Weisgraber, Karl H, Huang, Yadong, Mahley, Robert W
Published in The Journal of biological chemistry (14.06.2002)
Published in The Journal of biological chemistry (14.06.2002)
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Conformational flexibility in the apolipoprotein E amino-terminal domain structure determined from three new crystal forms: Implications for lipid binding
SEGELKE, BRENT W., FORSTNER, MICHAEL, KNAPP, MARK, TRAKHANOV, SERGEI D., PARKIN, SEAN, NEWHOUSE, YVONNE M., BELLAMY, HENRY D., WEISGRABER, KARL H., RUPP, BERNHARD
Published in Protein science (01.05.2000)
Published in Protein science (01.05.2000)
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Effects of polymorphism on the microenvironment of the LDL receptor-binding region of human apoE
Lund-Katz, S, Wehrli, S, Zaiou, M, Newhouse, Y, Weisgraber, K H, Phillips, M C
Published in Journal of lipid research (01.06.2001)
Published in Journal of lipid research (01.06.2001)
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New Insights into the Heparan Sulfate Proteoglycan-binding Activity of Apolipoprotein E
Libeu, Clare Peters, Lund-Katz, Sissel, Phillips, Michael C., Wehrli, Suzanne, Hernáiz, Maria J., Capila, Ishan, Linhardt, Robert J., Raffaı̈, Robert L., Newhouse, Yvonne M., Zhou, Fanyu, Weisgraber, Karl H.
Published in The Journal of biological chemistry (19.10.2001)
Published in The Journal of biological chemistry (19.10.2001)
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Screening and optimization strategies for macromolecular crystal growth
Cudney, R., Patel, S., Weisgraber, K., Newhouse, Y., McPherson, A.
Published in Acta crystallographica. Section D, Biological crystallography. (01.07.1994)
Published in Acta crystallographica. Section D, Biological crystallography. (01.07.1994)
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Expression and catalytic activities of protein tyrosine kinases (PTKs) Fyn and Lck in peripheral blood T cells from elderly humans stimulated through the T cell receptor (TCR)/CD3 complex
Whisler, Ronald L, Bagenstose, Scott E, Newhouse, Yvonne G, Carle, Kristen W
Published in Mechanisms of ageing and development (01.10.1997)
Published in Mechanisms of ageing and development (01.10.1997)
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Type III hyperlipoproteinemia associated with apolipoprotein E phenotype E3/3: structure and genetics of an apolipoprotein E3 variant
RALL, S. C, NEWHOUSE, Y. M, CLARKE, H. R. G, WEISGRABER, K. H, MCCARTHY, B. J, MAHLEY, R. W, BERSOT, T. P
Published in The Journal of clinical investigation (01.04.1989)
Published in The Journal of clinical investigation (01.04.1989)
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Apolipoprotein E;-low density lipoprotein receptor interaction. Influences of basic residue and amphipathic alpha-helix organization in the ligand
Zaiou, M, Arnold, K S, Newhouse, Y M, Innerarity, T L, Weisgraber, K H, Segall, M L, Phillips, M C, Lund-Katz, S
Published in Journal of lipid research (01.07.2000)
Published in Journal of lipid research (01.07.2000)
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Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia
Dong, L M, Parkin, S, Trakhanov, S D, Rupp, B, Simmons, T, Arnold, K S, Newhouse, Y M, Innerarity, T L, Weisgraber, K H
Published in Nature structural biology (01.08.1996)
Published in Nature structural biology (01.08.1996)
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Identification and characterization of a novel apolipoprotein E variant, apolipoprotein E3' (Arg136-->His): association with mild dyslipidemia and double pre-beta very low density lipoproteins
Minnich, A, Weisgraber, K H, Newhouse, Y, Dong, L M, Fortin, L J, Tremblay, M, Davignon, J
Published in Journal of lipid research (01.01.1995)
Published in Journal of lipid research (01.01.1995)
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Phosphorylation and coupling of ζ-chains to activated T-cell receptor (TCR)/CD3 complexes from peripheral blood T-cells of elderly humans
Whisler, Ronald L, Karanfilov, Chris I, Newhouse, Yvonne G, Fox, Charity C, Lakshmanan, Romola R, Liu, Beiqing
Published in Mechanisms of ageing and development (15.09.1998)
Published in Mechanisms of ageing and development (15.09.1998)
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Familial Defective Apolipoprotein B-100: Enhanced Binding of Monoclonal Antibody MB47 to Abnormal Low Density Lipoproteins
Weisgraber, Karl H., Innerarity, Thomas L., Newhouse, Yvonne M., Young, Stephen G., Arnold, Kay S., Krauss, Ronald M., Vega, Gloria L., Grundy, Scott M., Mahley, Robert W.
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.1988)
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.1988)
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Crystallization and Preliminary X-ray Analysis of Human Plasma Apolipoprotein C-I
Weisgraber, Karl H., Newhouse, Yvonne M., McPherson, Alexander
Published in Journal of molecular biology (11.02.1994)
Published in Journal of molecular biology (11.02.1994)
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Age-related impairments in TCR/CD3 activation of ZAP-70 are associated with reduced tyrosine phosphorylations of ζ-chains and p59fyn/p56lck in human T cells
WHISLER, R. L, MING CHEN, BEIQING LIU, NEWHOUSE, Y. G
Published in Mechanisms of ageing and development (02.11.1999)
Published in Mechanisms of ageing and development (02.11.1999)
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Differential expression of the α- and β-isoforms of protein kinase C in peripheral blood T and B cells from young and elderly adults
Whisler, Ronald L., Newhouse, Yvonne G., Grants, Iveta S., Hackshaw, Kevin V.
Published in Mechanisms of ageing and development (13.01.1995)
Published in Mechanisms of ageing and development (13.01.1995)
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Human low density lipoprotein receptor fragment. Successful refolding of a functionally active ligand-binding domain produced in Escherichia coli
Simmons, T. (University of California, San Francisco), Newhouse, Y.M, Arnold, K.S, Innerarity, T.L, Weisgraber, K.H
Published in The Journal of biological chemistry (10.10.1997)
Published in The Journal of biological chemistry (10.10.1997)
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Human B cell proliferative responses during aging. Reduced RNA synthesis and DNA replication after signal transduction by surface immunoglobulins compared to B cell antigenic determinants CD20 and CD40
WHISLER, R. L, WILLIAMS, J. W, NEWHOUSE, Y. G
Published in Mechanisms of ageing and development (02.12.1991)
Published in Mechanisms of ageing and development (02.12.1991)
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