In vitro and in silico Activity of Iridoids Against Leishmania amazonensis
Vendruscolo, Maria Helena, das Neves, Gustavo Machado, Kagami, Luciano Porto, Rodrigues Junior, Luiz Carlos, Nunes Diehl, Maria Luísa, Gnoatto, Simone Cristina Baggio, de Loreto Bordignon, Sérgio Augusto, Romão, Pedro Roosevelt Torres, Eifler-Lima, Vera Lucia, von Poser, Gilsane Lino
Published in Current drug discovery technologies (2019)
Published in Current drug discovery technologies (2019)
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Journal Article
Ethyl 6-Methyl-2-oxo-4-{4-[(1-phenyl-1H-1,2,3-triazol-4-yl)methoxy]phenyl}-1,2,3,4-tetrahydropyrimidine-5-carboxylate
Gonçalves, Itamar Luís, Azambuja, Gabriel Oliveira de, Davi, Leonardo, Gonçalves, Guilherme Arraché, Kagami, Luciano Porto, Neves, Gustavo Machado das, Silveira, João Pedro, Canto, Rômulo Faria Santos, Eifler-Lima, Vera Lucia
Published in MolBank (01.09.2019)
Published in MolBank (01.09.2019)
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Journal Article
Natural and synthetic coumarins as antileishmanial agents: A review
Gonçalves, Guilherme Arraché, Spillere, Adriano Ronchi, das Neves, Gustavo Machado, Kagami, Luciano Porto, von Poser, Gilsane Lino, Canto, Rômulo Faria Santos, Eifler-Lima, VeraLucia
Published in European journal of medicinal chemistry (01.10.2020)
Published in European journal of medicinal chemistry (01.10.2020)
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Journal Article
LaSOM 335, active against bladder cancer cells, interferes with Let‐60 (hRas) and reduces CD73 expression/activity
Kagami, Luciano Porto, Gonçalves, Itamar Luís, Silva, Álisson Coldebella, Silva, Aline Castro, Neves, Gustavo Machado, Göethel, Gabriela, Spillere, Adriano, Santos, Maitê Roxo, Figueiró, Fabrício, Garcia, Solange Cristina, Ávila, Daiana Silva, Battastini, Ana Maria Oliveira, Eifler‐Lima, Vera Lucia
Published in Chemical biology & drug design (01.09.2023)
Published in Chemical biology & drug design (01.09.2023)
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Journal Article
Ethyl 4-(2-fluorophenyl)-6-methyl-2-thioxo-1-(p-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
Gonçalves, Itamar, Porto Kagami, Luciano, Machado das Neves, Gustavo, Rockenbach, Liliana, Davi, Leonardo, Soares, Alceu, Garcia, Solange, Eifler-Lima, Vera
Published in MolBank (01.12.2018)
Published in MolBank (01.12.2018)
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Journal Article
Antitumoral activity of different Amaryllidaceae alkaloids: In vitro and in silico assays
Tallini, Luciana R., Machado das Neves, Gustavo, Vendruscolo, Maria Helena, Rezende-Teixeira, Paula, Borges, Warley, Bastida, Jaume, Costa-Lotufo, Letícia V., Eifler-Lima, Vera Lucia, Zuanazzi, José Angelo S.
Published in Journal of ethnopharmacology (15.07.2024)
Published in Journal of ethnopharmacology (15.07.2024)
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Journal Article
The role of alternative toxicological trials in drug discovery programs: The case of Caenorhabditis elegans and other methods
Göethel, Gabriela, Augsten, Lucas Volnei, das Neves, Gustavo Machado, Gonçalves, Itamar Luís, de Souza, João Pedro Silveira, Garcia, Solange Cristina, Eifler-Lima, Vera Lucia
Published in Current medicinal chemistry (01.01.2022)
Published in Current medicinal chemistry (01.01.2022)
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Journal Article
In Silico Prediction of ADMET/Drug-likeness Properties of Bioactive Phloroglucinols from Hypericum genus
da Silva, Camila Pires Machado, das Neves, Gustavo Machado, Poser, Gilsane Lino von, Eifler-Lima, Vera Lucia, Rates, Stela Maris Kuze
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01.01.2023)
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01.01.2023)
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Journal Article
New pharmacological findings linked to biphenyl DHPMs, kinesin Eg5 ligands: anticancer and antioxidant effects
Gonçalves, Itamar Luís, Rockenbach, Liliana, Göethel, Gabriela, Saüer, Elisa, Kagami, Luciano Porto, das Neves, Gustavo Machado, Munhoz, Thaís, Figueiró, Fabrício, Garcia, Solange Cristina, Oliveira Battastini, Ana Maria, Eifler-Lima, Vera Lucia
Published in Future medicinal chemistry (01.06.2020)
Published in Future medicinal chemistry (01.06.2020)
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Journal Article
Beyond the "Lock and Key" Paradigm: Targeting Lipid Rafts to Induce the Selective Apoptosis of Cancer Cells
Alves, Anna Carolina Schneider, Dias, Reinaldo Antonio, Kagami, Luciano Porto, das Neves, Gustavo Machado, Torres, Fernando Cidade, Eifler-Lima, Vera Lucia, Carvalho, Ivone, de Miranda Silva, Carolina, Kawano, Daniel Fabio
Published in Current medicinal chemistry (01.01.2018)
Published in Current medicinal chemistry (01.01.2018)
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Journal Article
LiGRO: a graphical user interface for protein–ligand molecular dynamics
Kagami, Luciano Porto, das Neves, Gustavo Machado, da Silva, Alan Wilter Sousa, Caceres, Rafael Andrade, Kawano, Daniel Fábio, Eifler-Lima, Vera Lucia
Published in Journal of molecular modeling (01.11.2017)
Published in Journal of molecular modeling (01.11.2017)
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Journal Article
Insights into Ecto-5'-Nucleotidase as a New Target for Cancer Therapy: A Medicinal Chemistry Study
Corbelini, Patricia Frasson, Figueiró, Fabrício, das Neves, Gustavo Machado, Andrade, Saulo, Kawano, Daniel Fábio, Oliveira Battastini, Ana Maria, Eifler-Lima, Vera Lucia
Published in Current medicinal chemistry (04.05.2015)
Published in Current medicinal chemistry (04.05.2015)
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Journal Article
Effect of N-1 arylation of monastrol on kinesin Eg5 inhibition in glioma cell lines
Goncalves, Itamar Luis, Rockenbach, Liliana, das Neves, Gustavo Machado, Goethel, Gabriela, Nascimento, Fabiana, Kagami, Luciano Porto, Figueiro, Fabricio, de Azambuja, Gabriel Oliveira, Dias, Amanda de Fraga, Amaro, Andressa, de Souza, Lauro Mera, Pitta, Ivan da Rocha, Avila, Daiana Silva, Kawano, Daniel Fabio, Garcia, Solange Cristina, Oliveira Battastinic, Ana Maria, Eifler-Lima, Vera Lucia
Published in MedChemComm (01.06.2018)
Published in MedChemComm (01.06.2018)
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Journal Article
Novel coumarins active against Trypanosoma cruzi and toxicity assessment using the animal model Caenorhabditis elegans
Soares, Fabiana Gomes Nascimento, Göethel, Gabriela, Kagami, Luciano Porto, das Neves, Gustavo Machado, Sauer, Elisa, Birriel, Estefania, Varela, Javier, Gonçalves, Itamar Luís, Von Poser, Gilsane, González, Mercedes, Kawano, Daniel Fábio, Paula, Fávero Reisdorfer, de Melo, Eduardo Borges, Garcia, Solange Cristina, Cerecetto, Hugo, Eifler-Lima, Vera Lucia
Published in BMC pharmacology & toxicology (19.12.2019)
Published in BMC pharmacology & toxicology (19.12.2019)
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Journal Article
Geo-Measures: A PyMOL plugin for protein structure ensembles analysis
Kagami, Luciano Porto, das Neves, Gustavo Machado, Timmers, Luís Fernando Saraiva Macedo, Caceres, Rafael Andrade, Eifler-Lima, Vera Lucia
Published in Computational biology and chemistry (01.08.2020)
Published in Computational biology and chemistry (01.08.2020)
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Journal Article
Targeting ecto-5′-nucleotidase: A comprehensive review into small molecule inhibitors and expression modulators
das Neves, Gustavo Machado, Kagami, Luciano Porto, Battastini, Ana Maria Oliveira, Figueiró, Fabrício, Eifler-Lima, Vera Lucia
Published in European journal of medicinal chemistry (05.02.2023)
Published in European journal of medicinal chemistry (05.02.2023)
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Journal Article
LaSOM 335, active against bladder cancer cells, interferes with Let‐60 ( h Ras ) and reduces CD 73 expression/activity
Kagami, Luciano Porto, Gonçalves, Itamar Luís, da Silva, Álisson Coldebella, Silva, Aline Castro, das Neves, Gustavo Machado, Göethel, Gabriela, Spillere, Adriano, dos Santos, Maitê Roxo, Figueiró, Fabrício, Garcia, Solange Cristina, Ávila, Daiana Silva, Battastini, Ana Maria Oliveira, Eifler‐Lima, Vera Lucia
Published in Chemical biology & drug design (01.09.2023)
Published in Chemical biology & drug design (01.09.2023)
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Journal Article