Mutant huntingtin impairs neurodevelopment in human brain organoids through CHCHD2-mediated neurometabolic failure
Lisowski, Pawel, Lickfett, Selene, Rybak-Wolf, Agnieszka, Menacho, Carmen, Le, Stephanie, Pentimalli, Tancredi Massimo, Notopoulou, Sofia, Dykstra, Werner, Oehler, Daniel, López-Calcerrada, Sandra, Mlody, Barbara, Otto, Maximilian, Wu, Haijia, Richter, Yasmin, Roth, Philipp, Anand, Ruchika, Kulka, Linda A. M., Meierhofer, David, Glazar, Petar, Legnini, Ivano, Telugu, Narasimha Swamy, Hahn, Tobias, Neuendorf, Nancy, Miller, Duncan C., Böddrich, Annett, Polzin, Amin, Mayatepek, Ertan, Diecke, Sebastian, Olzscha, Heidi, Kirstein, Janine, Ugalde, Cristina, Petrakis, Spyros, Cambridge, Sidney, Rajewsky, Nikolaus, Kühn, Ralf, Wanker, Erich E., Priller, Josef, Metzger, Jakob J., Prigione, Alessandro
Published in Nature communications (22.08.2024)
Published in Nature communications (22.08.2024)
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A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease
Boeddrich, Annett, Haenig, Christian, Neuendorf, Nancy, Blanc, Eric, Ivanov, Andranik, Kirchner, Marieluise, Schleumann, Philipp, Bayraktaroğlu, Irem, Richter, Matthias, Molenda, Christine Mirjam, Sporbert, Anje, Zenkner, Martina, Schnoegl, Sigrid, Suenkel, Christin, Schneider, Luisa-Sophie, Rybak-Wolf, Agnieszka, Kochnowsky, Bianca, Byrne, Lauren M, Wild, Edward J, Nielsen, Jørgen E, Dittmar, Gunnar, Peters, Oliver, Beule, Dieter, Wanker, Erich E
Published in Genome medicine (20.07.2023)
Published in Genome medicine (20.07.2023)
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Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington’s Disease Knock-in Mice
Schindler, Franziska, Praedel, Nicole, Neuendorf, Nancy, Kunz, Severine, Schnoegl, Sigrid, Mason, Michael A., Taxy, Bridget A., Bates, Gillian P., Khoshnan, Ali, Priller, Josef, Grimm, Jan, Maier, Marcel, Boeddrich, Annett, Wanker, Erich E.
Published in Frontiers in neuroscience (22.06.2021)
Published in Frontiers in neuroscience (22.06.2021)
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The polyphenol EGCG directly targets intracellular amyloid‐β aggregates and promotes their lysosomal degradation
Secker, Christopher, Motzny, Angelika Y., Kostova, Simona, Buntru, Alexander, Helmecke, Lucas, Reus, Laura, Steinfort, Robert, Brusendorf, Lydia, Boeddrich, Annett, Neuendorf, Nancy, Diez, Lisa, Schmieder, Peter, Schulz, Aline, Czekelius, Constantin, Wanker, Erich E.
Published in Journal of neurochemistry (01.07.2023)
Published in Journal of neurochemistry (01.07.2023)
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Sclerotiorin Stabilizes the Assembly of Nonfibrillar Abeta42 Oligomers with Low Toxicity, Seeding Activity, and Beta-sheet Content
Wiglenda, Thomas, Groenke, Nicole, Hoffmann, Waldemar, Manz, Christian, Diez, Lisa, Buntru, Alexander, Brusendorf, Lydia, Neuendorf, Nancy, Schnoegl, Sigrid, Haenig, Christian, Schmieder, Peter, Pagel, Kevin, Wanker, Erich E.
Published in Journal of molecular biology (27.03.2020)
Published in Journal of molecular biology (27.03.2020)
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The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice
Boeddrich, Annett, Babila, Julius T, Wiglenda, Thomas, Diez, Lisa, Jacob, Manuela, Nietfeld, Wilfried, Huska, Matthew R, Haenig, Christian, Groenke, Nicole, Buntru, Alexander, Blanc, Eric, Meier, Jochen C, Vannoni, Elisabetta, Erck, Christian, Friedrich, Beate, Martens, Henrik, Neuendorf, Nancy, Schnoegl, Sigrid, Wolfer, David P, Loos, Maarten, Beule, Dieter, Andrade-Navarro, Miguel A, Wanker, Erich E
Published in Cell chemical biology (17.01.2019)
Published in Cell chemical biology (17.01.2019)
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