hnRNPK Recruits PCGF3/5-PRC1 to the Xist RNA B-Repeat to Establish Polycomb-Mediated Chromosomal Silencing
Pintacuda, Greta, Wei, Guifeng, Roustan, Chloë, Kirmizitas, Burcu Anil, Solcan, Nicolae, Cerase, Andrea, Castello, Alfredo, Mohammed, Shabaz, Moindrot, Benoît, Nesterova, Tatyana B., Brockdorff, Neil
Published in Molecular cell (07.12.2017)
Published in Molecular cell (07.12.2017)
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Journal Article
A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing
Moindrot, Benoit, Cerase, Andrea, Coker, Heather, Masui, Osamu, Grijzenhout, Anne, Pintacuda, Greta, Schermelleh, Lothar, Nesterova, Tatyana B., Brockdorff, Neil
Published in Cell reports (Cambridge) (28.07.2015)
Published in Cell reports (Cambridge) (28.07.2015)
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Journal Article
PCGF3/5–PRC1 initiates Polycomb recruitment in X chromosome inactivation
Almeida, Mafalda, Pintacuda, Greta, Masui, Osamu, Koseki, Yoko, Gdula, Michal, Cerase, Andrea, Brown, David, Mould, Arne, Innocent, Cassandravictoria, Nakayama, Manabu, Schermelleh, Lothar, Nesterova, Tatyana B., Koseki, Haruhiko, Brockdorff, Neil
Published in Science (American Association for the Advancement of Science) (09.06.2017)
Published in Science (American Association for the Advancement of Science) (09.06.2017)
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Journal Article
Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2
Cooper, Sarah, Grijzenhout, Anne, Underwood, Elizabeth, Ancelin, Katia, Zhang, Tianyi, Nesterova, Tatyana B., Anil-Kirmizitas, Burcu, Bassett, Andrew, Kooistra, Susanne M., Agger, Karl, Helin, Kristian, Heard, Edith, Brockdorff, Neil
Published in Nature communications (28.11.2016)
Published in Nature communications (28.11.2016)
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Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells
von Meyenn, Ferdinand, Iurlaro, Mario, Habibi, Ehsan, Liu, Ning Qing, Salehzadeh-Yazdi, Ali, Santos, Fátima, Petrini, Edoardo, Milagre, Inês, Yu, Miao, Xie, Zhenqing, Kroeze, Leonie I., Nesterova, Tatyana B., Jansen, Joop H., Xie, Hehuang, He, Chuan, Reik, Wolf, Stunnenberg, Hendrik G.
Published in Molecular cell (16.06.2016)
Published in Molecular cell (16.06.2016)
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Systematic allelic analysis defines the interplay of key pathways in X chromosome inactivation
Nesterova, Tatyana B., Wei, Guifeng, Coker, Heather, Pintacuda, Greta, Bowness, Joseph S., Zhang, Tianyi, Almeida, Mafalda, Bloechl, Bianca, Moindrot, Benoit, Carter, Emma J., Alvarez Rodrigo, Ines, Pan, Qi, Bi, Ying, Song, Chun-Xiao, Brockdorff, Neil
Published in Nature communications (16.07.2019)
Published in Nature communications (16.07.2019)
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Journal Article
The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome
Gdula, Michal R., Nesterova, Tatyana B., Pintacuda, Greta, Godwin, Jonathan, Zhan, Ye, Ozadam, Hakan, McClellan, Michael, Moralli, Daniella, Krueger, Felix, Green, Catherine M., Reik, Wolf, Kriaucionis, Skirmantas, Heard, Edith, Dekker, Job, Brockdorff, Neil
Published in Nature communications (03.01.2019)
Published in Nature communications (03.01.2019)
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Journal Article
The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory
Ridings-Figueroa, Rebeca, Stewart, Emma R, Nesterova, Tatyana B, Coker, Heather, Pintacuda, Greta, Godwin, Jonathan, Wilson, Rose, Haslam, Aidan, Lilley, Fred, Ruigrok, Renate, Bageghni, Sumia A, Albadrani, Ghadeer, Mansfield, William, Roulson, Jo-An, Brockdorff, Neil, Ainscough, Justin F X, Coverley, Dawn
Published in Genes & development (01.05.2017)
Published in Genes & development (01.05.2017)
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Journal Article
Independent Mechanisms Target SMCHD1 to Trimethylated Histone H3 Lysine 9-Modified Chromatin and the Inactive X Chromosome
Brideau, Nicholas J., Coker, Heather, Gendrel, Anne-Valerie, Siebert, C. Alistair, Bezstarosti, Karel, Demmers, Jeroen, Poot, Raymond A., Nesterova, Tatyana B., Brockdorff, Neil
Published in Molecular and cellular biology (01.12.2015)
Published in Molecular and cellular biology (01.12.2015)
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Journal Article
Epigenetic Functions of Smchd1 Repress Gene Clusters on the Inactive X Chromosome and on Autosomes
Gendrel, Anne-Valerie, Tang, Y. Amy, Suzuki, Masako, Godwin, Jonathan, Nesterova, Tatyana B., Greally, John M., Heard, Edith, Brockdorff, Neil
Published in Molecular and Cellular Biology (01.08.2013)
Published in Molecular and Cellular Biology (01.08.2013)
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Journal Article
Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
Bowness, Joseph S., Nesterova, Tatyana B., Wei, Guifeng, Rodermund, Lisa, Almeida, Mafalda, Coker, Heather, Carter, Emma J., Kadaster, Artun, Brockdorff, Neil
Published in Cell reports (Cambridge) (17.05.2022)
Published in Cell reports (Cambridge) (17.05.2022)
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Journal Article
Spatial separation of Xist RNA and polycomb proteins revealed by superresolution microscopy
Cerase, Andrea, Smeets, Daniel, Tang, Y. Amy, Gdula, Michal, Kraus, Felix, Spivakov, Mikhail, Moindrot, Benoit, Leleu, Marion, Tattermusch, Anna, Demmerle, Justin, Nesterova, Tatyana B., Green, Catherine, Otte, Arie P., Schermelleh, Lothar, Brockdorff, Neil
Published in Proceedings of the National Academy of Sciences - PNAS (11.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (11.02.2014)
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Journal Article
Polycomb Group Proteins Ring1A/B Link Ubiquitylation of Histone H2A to Heritable Gene Silencing and X Inactivation
de Napoles, Mariana, Mermoud, Jacqueline E., Wakao, Rika, Tang, Y.Amy, Endoh, Mitusuhiro, Appanah, Ruth, Nesterova, Tatyana B., Silva, Jose, Otte, Arie P., Vidal, Miguel, Koseki, Haruhiko, Brockdorff, Neil
Published in Developmental cell (01.11.2004)
Published in Developmental cell (01.11.2004)
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Journal Article
Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells
von Meyenn, Ferdinand, Iurlaro, Mario, Habibi, Ehsan, Liu, Ning Qing, Salehzadeh-Yazdi, Ali, Santos, Fátima, Petrini, Edoardo, Milagre, Inês, Yu, Miao, Xie, Zhenqing, Kroeze, Leonie I., Nesterova, Tatyana B., Jansen, Joop H., Xie, Hehuang, He, Chuan, Reik, Wolf, Stunnenberg, Hendrik G.
Published in Molecular cell (16.06.2016)
Published in Molecular cell (16.06.2016)
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Journal Article
A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements
Elisaphenko, Eugeny A, Kolesnikov, Nikolay N, Shevchenko, Alexander I, Rogozin, Igor B, Nesterova, Tatyana B, Brockdorff, Neil, Zakian, Suren M
Published in PloS one (25.06.2008)
Published in PloS one (25.06.2008)
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Journal Article
Reactivation of the Paternal X Chromosome in Early Mouse Embryos
Mak, Winifred, Nesterova, Tatyana B., de Napoles, Mariana, Appanah, Ruth, Yamanaka, Shinya, Otte, Arie P., Brockdorff, Neil
Published in Science (American Association for the Advancement of Science) (30.01.2004)
Published in Science (American Association for the Advancement of Science) (30.01.2004)
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Journal Article
Establishment of Histone H3 Methylation on the Inactive X Chromosome Requires Transient Recruitment of Eed-Enx1 Polycomb Group Complexes
Silva, Jose, Mak, Winifred, Zvetkova, Ilona, Appanah, Ruth, Nesterova, Tatyana B, Webster, Zoe, Peters, Antoine H.F.M, Jenuwein, Thomas, Otte, Arie P, Brockdorff, Neil
Published in Developmental cell (01.04.2003)
Published in Developmental cell (01.04.2003)
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Journal Article
MicroRNAs of the miR-290–295 Family Maintain Bivalency in Mouse Embryonic Stem Cells
Graham, Bryony, Marcais, Antoine, Dharmalingam, Gopuraja, Carroll, Thomas, Kanellopoulou, Chryssa, Graumann, Johannes, Nesterova, Tatyana B., Bermange, Anna, Brazauskas, Pijus, Xella, Barbara, Kriaucionis, Skirmantas, Higgs, Douglas R., Brockdorff, Neil, Mann, Matthias, Fisher, Amanda G., Merkenschlager, Matthias
Published in Stem cell reports (10.05.2016)
Published in Stem cell reports (10.05.2016)
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Journal Article
Pluripotency factor binding and Tsix expression act synergistically to repress Xist in undifferentiated embryonic stem cells
Nesterova, Tatyana B, Senner, Claire E, Schneider, Janina, Alcayna-Stevens, Tilly, Tattermusch, Anna, Hemberger, Myriam, Brockdorff, Neil
Published in Epigenetics & chromatin (07.10.2011)
Published in Epigenetics & chromatin (07.10.2011)
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