Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing
Valletta, Simona, Thomas, Alexander, Meng, Yiran, Ren, Xiying, Drissen, Roy, Sengül, Hilal, Di Genua, Cristina, Nerlov, Claus
Published in Nature communications (14.08.2020)
Published in Nature communications (14.08.2020)
Get full text
Journal Article
Lineage-Biased Hematopoietic Stem Cells Are Regulated by Distinct Niches
Pinho, Sandra, Marchand, Tony, Yang, Eva, Wei, Qiaozhi, Nerlov, Claus, Frenette, Paul S.
Published in Developmental cell (12.03.2018)
Published in Developmental cell (12.03.2018)
Get full text
Journal Article
A transit-amplifying population underpins the efficient regenerative capacity of the testis
Carrieri, Claudia, Comazzetto, Stefano, Grover, Amit, Morgan, Marcos, Buness, Andreas, Nerlov, Claus, O'Carroll, Dónal
Published in The Journal of experimental medicine (05.06.2017)
Published in The Journal of experimental medicine (05.06.2017)
Get full text
Journal Article
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal
Pietras, Eric M., Mirantes-Barbeito, Cristina, Fong, Sarah, Loeffler, Dirk, Kovtonyuk, Larisa V., Zhang, SiYi, Lakshminarasimhan, Ranjani, Chin, Chih Peng, Techner, José-Marc, Will, Britta, Nerlov, Claus, Steidl, Ulrich, Manz, Markus G., Schroeder, Timm, Passegué, Emmanuelle
Published in Nature cell biology (01.06.2016)
Published in Nature cell biology (01.06.2016)
Get full text
Journal Article
CREB-C/EBPβ cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair
Ruffell, Daniela, Mourkioti, Foteini, Gambardella, Adriana, Kirstetter, Peggy, Lopez, Rodolphe G, Rosenthal, Nadia, Nerlov, Claus
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (13.10.2009)
Get full text
Journal Article
Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells
Carrelha, Joana, Meng, Yiran, Kettyle, Laura M., Luis, Tiago C., Norfo, Ruggiero, Alcolea, Verónica, Boukarabila, Hanane, Grasso, Francesca, Gambardella, Adriana, Grover, Amit, Högstrand, Kari, Lord, Allegra M., Sanjuan-Pla, Alejandra, Woll, Petter S., Nerlov, Claus, Jacobsen, Sten Eirik W.
Published in Nature (London) (01.02.2018)
Published in Nature (London) (01.02.2018)
Get full text
Journal Article
Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging
Ho, Ya-Hsuan, del Toro, Raquel, Rivera-Torres, José, Rak, Justyna, Korn, Claudia, García-García, Andrés, Macías, David, González-Gómez, Cristina, del Monte, Alberto, Wittner, Monika, Waller, Amie K., Foster, Holly R., López-Otín, Carlos, Johnson, Randall S., Nerlov, Claus, Ghevaert, Cedric, Vainchenker, William, Louache, Fawzia, Andrés, Vicente, Méndez-Ferrer, Simón
Published in Cell stem cell (05.09.2019)
Published in Cell stem cell (05.09.2019)
Get full text
Journal Article
Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
Grover, Amit, Sanjuan-Pla, Alejandra, Thongjuea, Supat, Carrelha, Joana, Giustacchini, Alice, Gambardella, Adriana, Macaulay, Iain, Mancini, Elena, Luis, Tiago C., Mead, Adam, Jacobsen, Sten Eirik W., Nerlov, Claus
Published in Nature communications (24.03.2016)
Published in Nature communications (24.03.2016)
Get full text
Journal Article
Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing
Drissen, Roy, Buza-Vidas, Natalija, Woll, Petter, Thongjuea, Supat, Gambardella, Adriana, Giustacchini, Alice, Mancini, Elena, Zriwil, Alya, Lutteropp, Michael, Grover, Amit, Mead, Adam, Sitnicka, Ewa, Jacobsen, Sten Eirik W, Nerlov, Claus
Published in Nature immunology (01.06.2016)
Published in Nature immunology (01.06.2016)
Get full text
Journal Article
Inflammatory signals directly instruct PU.1 in HSCs via TNF
Etzrodt, Martin, Ahmed, Nouraiz, Hoppe, Philipp S., Loeffler, Dirk, Skylaki, Stavroula, Hilsenbeck, Oliver, Kokkaliaris, Konstantinos D., Kaltenbach, Hans-Michael, Stelling, Jörg, Nerlov, Claus, Schroeder, Timm
Published in Blood (21.02.2019)
Published in Blood (21.02.2019)
Get full text
Journal Article
CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex
Schmidt, Luisa, Heyes, Elizabeth, Scheiblecker, Lisa, Eder, Thomas, Volpe, Giacomo, Frampton, Jon, Nerlov, Claus, Valent, Peter, Grembecka, Jolanta, Grebien, Florian
Published in Leukemia (01.07.2019)
Published in Leukemia (01.07.2019)
Get full text
Journal Article
Identification of two distinct pathways of human myelopoiesis
Drissen, Roy, Thongjuea, Supat, Theilgaard-Mönch, Kim, Nerlov, Claus
Published in Science immunology (24.05.2019)
Published in Science immunology (24.05.2019)
Get more information
Journal Article
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
Andrade-Navarro, Miguel A, Huska, Matthew R, Leutz, Achim, Bröske, Ann-Marie, Kharazi, Shabnam, Enns, Andreas, Rosenbauer, Frank, Nerlov, Claus, Jacobsen, Sten Eirik W, Prinz, Marco, Vockentanz, Lena, Kuhl, Christiane, Jaenisch, Rudolf, Mancini, Elena, Scheller, Marina
Published in Nature genetics (01.11.2009)
Published in Nature genetics (01.11.2009)
Get full text
Journal Article
CD34 and EPCR coordinately enrich functional murine hematopoietic stem cells under normal and inflammatory conditions
Rabe, Jennifer L., Hernandez, Giovanny, Chavez, James S., Mills, Taylor S., Nerlov, Claus, Pietras, Eric M.
Published in Experimental hematology (01.01.2020)
Published in Experimental hematology (01.01.2020)
Get full text
Journal Article
Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate
Grover, Amit, Mancini, Elena, Moore, Susan, Mead, Adam J, Atkinson, Deborah, Rasmussen, Kasper D, O'Carroll, Donal, Jacobsen, Sten Eirik W, Nerlov, Claus
Published in The Journal of experimental medicine (10.02.2014)
Published in The Journal of experimental medicine (10.02.2014)
Get full text
Journal Article