Discovery of TYRA-300: First Oral Selective FGFR3 Inhibitor for the Treatment of Urothelial Cancers and Achondroplasia
Hudkins, Robert L., Allen, Eric, Balcer, Alexandra, Hoffman, Isaac D., Iyer, Samhita, Neal, Melissa, Nelson, Kirk J., Rideout, Marc, Ye, Qing, Starrett, Jacqueline H., Patel, Piyush, Harris, Todd, Swanson, Ronald V., Bensen, Daniel C.
Published in Journal of medicinal chemistry (26.09.2024)
Published in Journal of medicinal chemistry (26.09.2024)
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Structure-Based Design of New Dihydrofolate Reductase Antibacterial Agents: 7‑(Benzimidazol-1-yl)-2,4-diaminoquinazolines
Lam, Thanh, Hilgers, Mark T, Cunningham, Mark L, Kwan, Bryan P, Nelson, Kirk J, Brown-Driver, Vickie, Ong, Voon, Trzoss, Michael, Hough, Grayson, Shaw, Karen Joy, Finn, John
Published in Journal of medicinal chemistry (13.02.2014)
Published in Journal of medicinal chemistry (13.02.2014)
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Absence of TetB identifies minocycline-susceptible isolates of Acinetobacter baumannii
Lomovskaya, Olga, Sun, Dongxu, Rubio-Aparicio, Debora, Nelson, Kirk J., Thamlikitkul, Visanu, Dudley, Michael N., Redell, Mark A.
Published in International journal of antimicrobial agents (01.09.2018)
Published in International journal of antimicrobial agents (01.09.2018)
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Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents
Tari, Leslie W, Li, Xiaoming, Trzoss, Michael, Bensen, Daniel C, Chen, Zhiyong, Lam, Thanh, Zhang, Junhu, Lee, Suk Joong, Hough, Grayson, Phillipson, Doug, Akers-Rodriguez, Suzanne, Cunningham, Mark L, Kwan, Bryan P, Nelson, Kirk J, Castellano, Amanda, Locke, Jeff B, Brown-Driver, Vickie, Murphy, Timothy M, Ong, Voon S, Pillar, Chris M, Shinabarger, Dean L, Nix, Jay, Lightstone, Felice C, Wong, Sergio E, Nguyen, Toan B, Shaw, Karen J, Finn, John
Published in PloS one (26.12.2013)
Published in PloS one (26.12.2013)
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Distinguishing on-target versus off-target activity in early antibacterial drug discovery using a macromolecular synthesis assay
Cunningham, Mark L, Kwan, Bryan P, Nelson, Kirk J, Bensen, Daniel C, Shaw, Karen J
Published in Journal of biomolecular screening (01.10.2013)
Published in Journal of biomolecular screening (01.10.2013)
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Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors
Tari, Leslie W., Hoffman, Isaac D., Bensen, Daniel C., Hunter, Michael J., Nix, Jay, Nelson, Kirk J., McRee, Duncan E., Swanson, Ronald V.
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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681. In vitro Activity of the β-Lactamase Inhibitor QPX7728 in Combination with Several β-Lactams Against Acinetobacter baumannii (AB) and Pseudomonas aeruginosa (PSA)
Lomovskaya, Olga, Lindley, Jill, Rubio-Aparicio, Debora, Nelson, Kirk J, Castanheira, Mariana
Published in Open forum infectious diseases (23.10.2019)
Published in Open forum infectious diseases (23.10.2019)
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