Efficient and versatile synthesis of dipeptide isosteres containing .gamma.- or .delta.-lactams
Zydowsky, Thomas M, Dellaria, Joseph F, Nellans, Hugh N
Published in Journal of organic chemistry (01.11.1988)
Published in Journal of organic chemistry (01.11.1988)
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Journal Article
Effect of Novel Motilide ABT-229 versus Erythromycin and Cisapride on Gastric Emptying in Dogs
Cowles, V E, Nellans, H N, Seifert, T R, Besecke, L M, Segreti, J A, Mohning, K M, Faghih, R, Verlinden, M H, Wegner, C D
Published in The Journal of pharmacology and experimental therapeutics (01.06.2000)
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Published in The Journal of pharmacology and experimental therapeutics (01.06.2000)
Journal Article
Gastrointestinal motor effects of erythromycin in humans
Sarna, S K, Soergel, K H, Koch, T R, Stone, J E, Wood, C M, Ryan, R P, Arndorfer, R C, Cavanaugh, J H, Nellans, H N, Lee, M B
Published in Gastroenterology (New York, N.Y. 1943) (01.12.1991)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.1991)
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Journal Article
Synthesis of 4''-Deoxy Motilides: Identification of a Potent and Orally Active Prokinetic Drug Candidate
Lartey, Paul A, Nellans, Hugh N, Faghih, Ramin, Petersen, Albert, Edwards, Carla M, Freiberg, Leslie, Quigley, Sherry, Marsh, Kennan, Klein, Larry L, Plattner Jacob J
Published in Journal of medicinal chemistry (01.05.1995)
Published in Journal of medicinal chemistry (01.05.1995)
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Journal Article
Azole Endothelin Antagonists. 3. Using Δ log P as a Tool To Improve Absorption
von Geldern, Thomas W, Hoffman, Daniel J, Kester, Jeffrey A, Nellans, Hugh N, Dayton, Brian D, Calzadilla, Samuel V, Marsh, Kennan C, Hernandez, Lisa, Chiou, William, Dixon, Douglas B, Wu-Wong, Jinshyun R, Opgenorth, Terry J
Published in Journal of medicinal chemistry (16.02.1996)
Published in Journal of medicinal chemistry (16.02.1996)
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Journal Article
Suppression by cathepsin L inhibitors of the invasion of amnion membranes by murine cancer cells
YAGEL, S, WARNER, A. H, NELLANS, H. N, LALA, P. K, WAGHORNE, C, DENHARDT, D. T
Published in Cancer research (Chicago, Ill.) (01.07.1989)
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Published in Cancer research (Chicago, Ill.) (01.07.1989)
Journal Article
Synthesis of 9-Deoxo-4‘‘-deoxy-6,9-epoxyerythromycin Derivatives: Novel and Acid-Stable Motilides
Faghih, Ramin, Lartey, Paul A, Nellans, Hugh N, Seif, Louis, Burnell-Curty, Cynthia, Klein, Larry L, Thomas, Paul, Petersen, Albert, Borre, Anthony, Pagano, Thomas, Kim, Ki Hwan, Heindel, Matthew, Bennani, Youssef L, Plattner, Jacob J
Published in Journal of medicinal chemistry (27.08.1998)
Published in Journal of medicinal chemistry (27.08.1998)
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Journal Article
Stabilization of the N-terminal residues of luteinizing hormone-releasing hormone agonists and the effect on pharmacokinetics
Haviv, Fortuna, Fitzpatrick, Timothy D, Nichols, Charles J, Swenson, Rolf E, Bush, Eugene N, Diaz, Gilbert, Nguyen, A, Nellans, Hugh N, Hoffman, Daniel J
Published in Journal of medicinal chemistry (01.10.1992)
Published in Journal of medicinal chemistry (01.10.1992)
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Journal Article
Azido glycols: potent, low molecular weight renin inhibitors containing an unusual post scissile site residue
Rosenberg, Saul H, Woods, Keith W, Kleinert, Hollis D, Stein, Herman, Nellans, Hugh N, Hoffman, Daniel J, Spanton, Stephen G, Pyter, Richard A, Cohen, Jerome
Published in Journal of medicinal chemistry (01.06.1989)
Published in Journal of medicinal chemistry (01.06.1989)
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Journal Article
Effect of N-methyl substitution of the peptide bonds in luteinizing hormone-releasing hormone agonists
Haviv, Fortuna, Fitzpatrick, Timothy D, Swenson, Rolf E, Nichols, Charles J, Mort, Nicholas A, Bush, Eugene N, Diaz, Gilbert, Bammert, Gary, Nguyen, A
Published in Journal of medicinal chemistry (01.02.1993)
Published in Journal of medicinal chemistry (01.02.1993)
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Journal Article
Preparation of 9-deoxo-4″-deoxy-6,9-epoxyerythromycin lactams “motilactides”: Potent and orally active prokinetic agents
Faghih, Ramin, Nellans, Hugh N., Lartey, Paul A., Petersen, Albert, Marsh, Kennan, Bennani, Youssef L., Plattner, Jacob J.
Published in Bioorganic & medicinal chemistry letters (07.04.1998)
Published in Bioorganic & medicinal chemistry letters (07.04.1998)
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Journal Article
Synthesis of 8(R),9(R)-9-deoxo-4''-deoxy-6,9-epoxyerythromycin: potent motilides
Faghih, Ramin, Burnell-Curty, Cynthia, Lartey, Paul A., Petersen, Albert, Klein, Larry L., Bennani, Youssef L., Nellans, Hugh N.
Published in European journal of medicinal chemistry (01.03.1999)
Published in European journal of medicinal chemistry (01.03.1999)
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Journal Article
3H-labeling of prokinetic motilide ABT-229 for biodistribution and metabolism studies
Faghih, Ramin, Burnell-Curty, Cynthia, Surber, Bruce, Shoghi, Simin, Borre, Anthony, Yao, Ye, Lartey, Paul A., Nellans, Hugh N.
Published in Journal of labelled compounds & radiopharmaceuticals (01.07.1996)
Published in Journal of labelled compounds & radiopharmaceuticals (01.07.1996)
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