The mannose receptor negatively modulates the Toll-like receptor 4–aryl hydrocarbon receptor–indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization
Salazar, Fabián, MSc, Hall, Laurence, BSc, Negm, Ola H., PhD, Awuah, Dennis, MSc, Tighe, Patrick J., PhD, Shakib, Farouk, PhD, FRCPath, Ghaemmaghami, Amir M., MD, PhD
Published in Journal of allergy and clinical immunology (01.06.2016)
Published in Journal of allergy and clinical immunology (01.06.2016)
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Journal Article
Clinical and biological significance of glucocorticoid receptor (GR) expression in breast cancer
Abduljabbar, Rezvan, Negm, Ola H., Lai, Chun-Fui, Jerjees, Dena A., Al-Kaabi, Methaq, Hamed, Mohamed R., Tighe, Patrick J., Buluwela, Lakjaya, Mukherjee, Abhik, Green, Andrew R., Ali, Simak, Rakha, Emad A., Ellis, Ian O.
Published in Breast cancer research and treatment (01.04.2015)
Published in Breast cancer research and treatment (01.04.2015)
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Journal Article
Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response protein
Alshareeda, Alaa Tarig, Negm, Ola H., Aleskandarany, Mohammed A., Green, Andrew R., Nolan, Christopher, TigHhe, Patrick J., Madhusudan, Srinivasan, Ellis, Ian O., Rakha, Emad A.
Published in Breast cancer research and treatment (01.08.2016)
Published in Breast cancer research and treatment (01.08.2016)
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Journal Article
Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer
Alshareeda, Alaa T., Negm, Ola H., Albarakati, Nada, Green, Andrew R., Nolan, Christopher, Sultana, Rebeka, Madhusudan, Srinivasan, benHasouna, Ahmed, Tighe, Paddy, Ellis, Ian O., Rakha, Emad A.
Published in Breast cancer research and treatment (01.06.2013)
Published in Breast cancer research and treatment (01.06.2013)
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Journal Article
Human Blood Autoantibodies in the Detection of Colorectal Cancer
Negm, Ola H, Hamed, Mohamed R, Schoen, Robert E, Whelan, Richard L, Steele, Robert J, Scholefield, John, Dilnot, Elizabeth M, Shantha Kumara, H M C, Robertson, John F R, Sewell, Herbert F
Published in PloS one (06.07.2016)
Published in PloS one (06.07.2016)
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Journal Article
Epithelial mesenchymal transition in early invasive breast cancer: an immunohistochemical and reverse phase protein array study
Aleskandarany, Mohammed A., Negm, Ola H., Green, Andrew R., Ahmed, Mohamed A. H., Nolan, Christopher C., Tighe, Patrick J., Ellis, Ian O., Rakha, Emad A.
Published in Breast cancer research and treatment (01.06.2014)
Published in Breast cancer research and treatment (01.06.2014)
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Journal Article
Clinical utility of reverse phase protein array for molecular classification of breast cancer
Negm, Ola H., Muftah, Abir A., Aleskandarany, Mohammed A., Hamed, Mohamed R., Ahmad, Dena A. J., Nolan, Christopher C., Diez-Rodriguez, Maria, Tighe, Patrick J., Ellis, Ian O., Rakha, Emad A., Green, Andrew R.
Published in Breast cancer research and treatment (01.01.2016)
Published in Breast cancer research and treatment (01.01.2016)
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Journal Article
Development and Validation of Protein Microarray Technology for Simultaneous Inflammatory Mediator Detection in Human Sera
Fairclough, Lucy C., Tighe, Patrick J., Todd, Ian, Tubby, Carolyn, Hamed, Mohamed R., Negm, Ola H., Selvarajah, Senthooran, Harrison, Tim
Published in Mediators of Inflammation (01.01.2014)
Published in Mediators of Inflammation (01.01.2014)
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Journal Article
A pro‐inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor‐associated periodic syndrome (TRAPS)
Negm, Ola H., Mannsperger, Heiko A., McDermott, Elizabeth M., Drewe, Elizabeth, Powell, Richard J., Todd, Ian, Fairclough, Lucy C., Tighe, Patrick J.
Published in European journal of immunology (01.07.2014)
Published in European journal of immunology (01.07.2014)
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Journal Article
Characterization of Behavioral, Signaling and Cytokine Alterations in a Rat Neurodevelopmental Model for Schizophrenia, and Their Reversal by the 5-HT6 Receptor Antagonist SB-399885
Shortall, Sinead E., Negm, Ola H., Fowler, Maxine, Fairclough, Lucy C., Tighe, Patrick J., Wigmore, Peter M., King, Madeleine V.
Published in Molecular neurobiology (01.09.2018)
Published in Molecular neurobiology (01.09.2018)
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Journal Article
The novel S59P mutation in the TNFRSF1A gene identified in an adult onset TNF receptor associated periodic syndrome (TRAPS) constitutively activates NF-κB pathway
Greco, Eliana, Aita, Ada, Galozzi, Paola, Gava, Alessandra, Sfriso, Paolo, Negm, Ola H, Tighe, Patrick, Caso, Francesco, Navaglia, Filippo, Dazzo, Emanuela, De Bortoli, Marzia, Rampazzo, Alessandra, Obici, Laura, Donadei, Simona, Merlini, Giampaolo, Plebani, Mario, Todd, Ian, Basso, Daniela, Punzi, Leonardo
Published in Arthritis research & therapy (03.04.2015)
Published in Arthritis research & therapy (03.04.2015)
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Journal Article
Clinicopathological and prognostic significance of mitogen-activated protein kinases (MAPK) in breast cancers
Ahmad, Dena A. J., Negm, Ola H., Alabdullah, M. Layth, Mirza, Sameer, Hamed, Mohamed R., Band, Vimla, Green, Andrew R., Ellis, Ian O., Rakha, Emad A.
Published in Breast cancer research and treatment (01.10.2016)
Published in Breast cancer research and treatment (01.10.2016)
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Journal Article
SUMOylation proteins in breast cancer
Alshareeda, Alaa T., Negm, Ola H., Green, Andrew R., Nolan, Christopher, Tighe, Paddy, Albarakati, Nada, Sultana, Rebeka, Madhusudan, Srinivasan, Ellis, Ian O., Rakha, Emad A.
Published in Breast cancer research and treatment (01.04.2014)
Published in Breast cancer research and treatment (01.04.2014)
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Journal Article
The prognostic significance of STAT3 in invasive breast cancer: analysis of protein and mRNA expressions in large cohorts
Aleskandarany, Mohammed A., Agarwal, Devika, Negm, Ola H., Ball, Graham, Elmouna, Ahmed, Ashankyty, Ibraheem, Nuglozeh, Edem, Fazaludeen, Mohammad F., Diez-Rodriguez, Maria, Nolan, Christopher C., Tighe, Patrick J., Green, Andrew R., Ellis, Ian O., Rakha, Emad A.
Published in Breast cancer research and treatment (01.02.2016)
Published in Breast cancer research and treatment (01.02.2016)
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Journal Article
Prognostic and biological significance of peroxisome proliferator-activated receptor-gamma in luminal breast cancer
Abduljabbar, Rezvan, Al-Kaabi, Methaq Mueen, Negm, Ola H., Jerjees, Dena, Muftah, Abir A., Mukherjee, Abhik, Lai, Chun F., Buluwela, Laki, Ali, Simak, Tighe, Patrick J., Green, Andrew, Ellis, Ian, Rakha, Emad
Published in Breast cancer research and treatment (01.04.2015)
Published in Breast cancer research and treatment (01.04.2015)
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Journal Article
Tumour necrosis factor receptor I blockade shows that TNF‐dependent and TNF‐independent mechanisms synergise in TNF receptor associated periodic syndrome
Fairclough, Lucy C., Stoop, A. Allart, Negm, Ola H., Radford, Paul M., Tighe, Patrick J., Todd, Ian
Published in European journal of immunology (01.10.2015)
Published in European journal of immunology (01.10.2015)
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Journal Article
Autoantibodies of IgM and IgG classes show differences in recognition of multiple autoantigens in chronic obstructive pulmonary disease
Shindi, Reham, Almehairi, Amna, Negm, Ola H., Kalsheker, Noor, Gale, Nichola S., Shale, Dennis J., Harrison, Timothy W., Bolton, Charlotte E., John, Michelle, Todd, Ian, Tighe, Patrick J., Fairclough, Lucy C.
Published in Clinical immunology (Orlando, Fla.) (01.10.2017)
Published in Clinical immunology (Orlando, Fla.) (01.10.2017)
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Journal Article
A signalome screening approach in the autoinflammatory disease TNF receptor associated periodic syndrome (TRAPS) highlights the anti-inflammatory properties of drugs for repurposing
Todd, Ian, Negm, Ola H., Reps, Jenna, Radford, Paul, Figueredo, Grazziela, McDermott, Elizabeth M., Drewe, Elizabeth, Powell, Richard J., Bainbridge, Susan, Hamed, Mohamed, Crouch, Sharon, Garibaldi, Jon, St-Gallay, Steve, Fairclough, Lucy C., Tighe, Patrick J.
Published in Pharmacological research (01.11.2017)
Published in Pharmacological research (01.11.2017)
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Journal Article