Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x- Deficient Mice
Motoyama, Noboru, Wang, Fanping, Roth, Kevin A., Sawa, Hirofumi, Nakayama, Kei-ichi, Nakayama, Keiko, Negishi, Izumi, Senju, Satoru, Zhang, Qing, Fujii, Satoshi, Loh, Dennis Y.
Published in Science (American Association for the Advancement of Science) (10.03.1995)
Published in Science (American Association for the Advancement of Science) (10.03.1995)
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Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene
Hamasaki, A, Sendo, F, Nakayama, K, Ishida, N, Negishi, I, Hatakeyama, S
Published in The Journal of experimental medicine (07.12.1998)
Published in The Journal of experimental medicine (07.12.1998)
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Essential role for ZAP-70 in both positive and negative selection of thymocytes
Negishi, Izumi, Motoyama, Noboru, Nakayama, Kei-ichi, Nakayama, Keiko, Senju, Satoru, Hatakeyama, Shigetsugu, Zhang, Qing, Chan, Andrew C, Loh, Dennis Y
Published in Nature (London) (03.08.1995)
Published in Nature (London) (03.08.1995)
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Journal Article
The Syk and ZAP-70 SH2-Containing Tyrosine Kinases are Implicated in Pre-T Cell Receptor Signaling
Cheng, Alec M., Negishi, Izumi, Anderson, Steven J., Chan, Andrew C., Bolen, Joseph, Loh, Dennis Y., Pawson, Tony
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.1997)
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Journal Article
Disappearance of the Lymphoid System in Bcl-2 Homozygous Mutant Chimeric Mice
Nakayama, Kei-ichi, Nakayama, Keiko, Negishi, Izumi, Kuida, Keisuke, Shinkai, Yoichi, Louie, Marjorie C., Fields, Larry E., Lucas, Phillip J., Stewart, Valerie, Alt, Frederick W., Loh, Dennis Y.
Published in Science (American Association for the Advancement of Science) (17.09.1993)
Published in Science (American Association for the Advancement of Science) (17.09.1993)
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Deficiency of phospholipase C-γ1 impairs renal development and hematopoiesis
Shirane, Masatoshi, Sawa, Hirofumi, Kobayashi, Yoshiyasu, Nakano, Toru, Kitajima, Kenji, Shinkai, Yoichi, Nagashima, Kazuo, Negishi, Izumi
Published in Development (Cambridge) (15.12.2001)
Published in Development (Cambridge) (15.12.2001)
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A Spontaneously Arising Mutation in the DLAARN Motif of Murine ZAP-70 Abrogates Kinase Activity and Arrests Thymocyte Development
Wiest, David L, Ashe, Jennifer M, Howcroft, T.Kevin, Lee, Hon-Man, Kemper, Debbie M, Negishi, Izumi, Singer, Dinah S, Singer, Alfred, Abe, Ryo
Published in Immunity (Cambridge, Mass.) (01.06.1997)
Published in Immunity (Cambridge, Mass.) (01.06.1997)
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Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
Sakaguchi, Shimon, Sakaguchi, Noriko, Takahashi, Takeshi, Hata, Hiroshi, Nomura, Takashi, Tagami, Tomoyuki, Yamazaki, Sayuri, Sakihama, Toshiko, Matsutani, Takaji, Negishi, Izumi, Nakatsuru, Syuichi
Published in Nature (27.11.2003)
Published in Nature (27.11.2003)
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Interaction of pigeon cytochrome c-(43–58) peptide analogs with either T cell antigen receptor or I-Ab molecule
Itoh, Y, Kajino, K, Ogasawara, K, Takahashi, A, Namba, K, Negishi, I, Matsuki, N, Iwabuchi, K, Kakinuma, M, Good, R A, Onoé, K
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.1997)
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Journal Article
Functional significance of the Fas molecule in naive lymphocytes
Senju, Satoru, Negishl, Izumi, Motoyama, Noboru, Wang, Fanping, Nakayama, Kei-ichi, Nakayama, Keiko, Lucas, Philip J., Hatakeyama, Shigetsugu, Zhang, Qing, Yonehara, Shin, Loh, Dennis Y.
Published in International immunology (01.03.1996)
Published in International immunology (01.03.1996)
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Activation of Antigen-Specific Cytotoxic T Lymphocytes by β2-Microglobulin or TAP1 Gene Disruption and the Introduction of Recipient-Matched MHC Class I Gene in Allogeneic Embryonic Stem Cell-Derived Dendritic Cells
Matsunaga, Yusuke, Fukuma, Daiki, Hirata, Shinya, Fukushima, Satoshi, Haruta, Miwa, Ikeda, Tokunori, Negishi, Izumi, Nishimura, Yasuharu, Senju, Satoru
Published in The Journal of immunology (1950) (01.11.2008)
Published in The Journal of immunology (1950) (01.11.2008)
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Targeted Disruption of Bcl-2αβ in Mice: Occurrence of Gray Hair, Polycystic Kidney Disease, and Lymphocytopenia
Nakayama, Keiko, Nakayama, Kei-Ichi, Negishi, Izumi, Kuida, Keisuke, Sawa, Hirofumi, Loh, Dennis Y.
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.1994)
Published in Proceedings of the National Academy of Sciences - PNAS (26.04.1994)
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Journal Article
Distribution of MEL-14+ cells in various lymphoid tissues
Iwabuchi, K, Ohgama, J, Ogasawara, K, Iwabuchi, C, Negishi, I, Good, R A, Onoé, K
Published in Immunobiology (1979) (01.03.1991)
Published in Immunobiology (1979) (01.03.1991)
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Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response
Lucas, PJ, Negishi, I, Nakayama, K, Fields, LE, Loh, DY
Published in The Journal of immunology (1950) (01.06.1995)
Published in The Journal of immunology (1950) (01.06.1995)
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Journal Article
Defective development of NK1.1+ T-cell antigen receptor αβ+ cells in zeta-associated protein 70 null mice with an accumulation of NK1.1+CD3− NK-like cells in the thymus
Iwabuchi, Kazuya, Iwabuchi, Chikako, Tone, Saori, Itoh, Daisuke, Tosa, Noriko, Negishi, Izumi, Ogasawara, Kazumasa, Uede, Toshimitsu, Onoé, Kazunori
Published in Blood (15.03.2001)
Published in Blood (15.03.2001)
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