Transient receptor potential A1 mediates an osmotically activated ion channel
Zhang, Xu-Feng, Chen, Jun, Faltynek, Connie R., Moreland, Robert B., Neelands, Torben R.
Published in The European journal of neuroscience (01.02.2008)
Published in The European journal of neuroscience (01.02.2008)
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Journal Article
Coexpression and activation of TRPV1 suppress the activity of the KCNQ2/3 channel
Zhang, Xu-Feng, Han, Ping, Neelands, Torben R, McGaraughty, Steve, Honore, Prisca, Surowy, Carol S, Zhang, Di
Published in The Journal of general physiology (01.09.2011)
Published in The Journal of general physiology (01.09.2011)
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A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel and Selective Transient Receptor Potential Type V1 Receptor Antagonist, Blocks Channel Activation by Vanilloids, Heat, and Acid
El Kouhen, Rachid, Surowy, Carol S, Bianchi, Bruce R, Neelands, Torben R, McDonald, Heath A, Niforatos, Wende, Gomtsyan, Arthur, Lee, Chih-Hung, Honore, Prisca, Sullivan, James P, Jarvis, Michael F, Faltynek, Connie R
Published in The Journal of pharmacology and experimental therapeutics (01.07.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2005)
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Journal Article
TRPV1b overexpression negatively regulates TRPV1 responsiveness to capsaicin, heat and low pH in HEK293 cells
Vos, Melissa H., Neelands, Torben R., McDonald, Heath A., Choi, Won, Kroeger, Paul E., Puttfarcken, Pamela S., Faltynek, Connie R., Moreland, Robert B., Han, Ping
Published in Journal of neurochemistry (01.11.2006)
Published in Journal of neurochemistry (01.11.2006)
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Journal Article
(R)-(5-tert-Butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) Blocks Polymodal Activation of Transient Receptor Potential Vanilloid 1 Receptors in Vitro and Heat-Evoked Firing of Spinal Dorsal Horn Neurons in Vivo
Surowy, Carol S, Neelands, Torben R, Bianchi, Bruce R, McGaraughty, Steve, El Kouhen, Rachid, Han, Ping, Chu, Katharine L, McDonald, Heath A, Vos, Melissa, Niforatos, Wende, Bayburt, Erol K, Gomtsyan, Arthur, Lee, Chih-Hung, Honore, Prisca, Sullivan, James P, Jarvis, Michael F, Faltynek, Connie R
Published in The Journal of pharmacology and experimental therapeutics (01.09.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2008)
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Journal Article
Characterization of A-425619 at native TRPV1 receptors: A comparison between dorsal root ganglia and trigeminal ganglia
McDonald, Heath A., Neelands, Torben R., Kort, Michael, Han, Ping, Vos, Melissa H., Faltynek, Connie R., Moreland, Robert B., Puttfarcken, Pamela S.
Published in European journal of pharmacology (31.10.2008)
Published in European journal of pharmacology (31.10.2008)
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Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222
Singh, Ashvani K, Fan, Yihong, Balut, Corina, Alani, Sara, Manelli, Arlene M, Swensen, Andrew M, Jia, Ying, Neelands, Torben R, Vortherms, Timothy A, Liu, Bo, Searle, Xenia B, Wang, Xueqing, Gao, Wenqing, Hwang, Tzyh-Chang, Ren, Hong Y, Cyr, Douglas, Kym, Philip R, Conrath, Katja, Tse, Chris
Published in The Journal of pharmacology and experimental therapeutics (01.01.2020)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2020)
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Journal Article
Acidification of Rat TRPV1 Alters the Kinetics of Capsaicin Responses
Neelands, Torben R, Jarvis, Michael F, Han, Ping, Faltynek, Connie R, Surowy, Carol S
Published in Molecular pain (28.09.2005)
Published in Molecular pain (28.09.2005)
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[3H]A-778317 [1-((R)-5-tert-Butyl-indan-1-yl)-3-isoquinolin-5-yl-urea]: a Novel, Stereoselective, High-Affinity Antagonist Is a Useful Radioligand for the Human Transient Receptor Potential Vanilloid-1 (TRPV1) Receptor
Bianchi, Bruce R, El Kouhen, Rachid, Neelands, Torben R, Lee, Chih-Hung, Gomtsyan, Arthur, Raja, Shirish N, Vaidyanathan, Sriajan N, Surber, Bruce, McDonald, Heath A, Surowy, Carol S, Faltynek, Connie R, Moreland, Robert B, Jarvis, Michael F, Puttfarcken, Pamela S
Published in The Journal of pharmacology and experimental therapeutics (01.10.2007)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2007)
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Journal Article
Pharmacology of modality-specific transient receptor potential vanilloid-1 antagonists that do not alter body temperature
Reilly, Regina M, McDonald, Heath A, Puttfarcken, Pamela S, Joshi, Shailen K, Lewis, LaGeisha, Pai, Madhavi, Franklin, Pamela H, Segreti, Jason A, Neelands, Torben R, Han, Ping, Chen, Jun, Mantyh, Patrick W, Ghilardi, Joseph R, Turner, Teresa M, Voight, Eric A, Daanen, Jerome F, Schmidt, Robert G, Gomtsyan, Arthur, Kort, Michael E, Faltynek, Connie R, Kym, Philip R
Published in The Journal of pharmacology and experimental therapeutics (01.08.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2012)
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Discovery of (R)‑1-(7-Chloro-2,2-bis(fluoromethyl)chroman-4-yl)-3-(3-methylisoquinolin-5-yl)urea (A-1165442): A Temperature-Neutral Transient Receptor Potential Vanilloid‑1 (TRPV1) Antagonist with Analgesic Efficacy
Voight, Eric A, Gomtsyan, Arthur R, Daanen, Jerome F, Perner, Richard J, Schmidt, Robert G, Bayburt, Erol K, DiDomenico, Stanley, McDonald, Heath A, Puttfarcken, Pamela S, Chen, Jun, Neelands, Torben R, Bianchi, Bruce R, Han, Ping, Reilly, Regina M, Franklin, Pamela H, Segreti, Jason A, Nelson, Richard A, Su, Zhi, King, Andrew J, Polakowski, James S, Baker, Scott J, Gauvin, Donna M, Lewis, LaGeisha R, Mikusa, Joseph P, Joshi, Shailen K, Faltynek, Connie R, Kym, Philip R, Kort, Michael E
Published in Journal of medicinal chemistry (11.09.2014)
Published in Journal of medicinal chemistry (11.09.2014)
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Functional Expression of L-, N-, P/Q-, and R-Type Calcium Channels in the Human NT2-N Cell Line
Neelands, Torben R, King, Anthony P. J, Macdonald, Robert L
Published in Journal of neurophysiology (01.12.2000)
Published in Journal of neurophysiology (01.12.2000)
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A-995662 [(R)-8-(4-methyl-5-(4-(trifluoromethyl)phenyl)oxazol-2-ylamino)-1,2,3,4-tetrahydronaphthalen-2-ol], a novel, selective TRPV1 receptor antagonist, reduces spinal release of glutamate and CGRP in a rat knee joint pain model
Puttfarcken, Pamela S., Han, Ping, Joshi, Shailen K., Neelands, Torben R., Gauvin, Donna M., Baker, Scott J., Lewis, La Geisha R., Bianchi, Bruce R., Mikusa, Joseph P., Koenig, John R., Perner, Richard J., Kort, Michael E., Honore, Prisca, Faltynek, Connie R., Kym, Philip R., Reilly, Regina M.
Published in Pain (Amsterdam) (01.08.2010)
Published in Pain (Amsterdam) (01.08.2010)
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2′, 3′‐ O ‐(2,4,6,Trinitrophenyl)‐ATP and A‐317491 are competitive antagonists at a slowly desensitizing chimeric human P2X 3 receptor
Neelands, Torben R, Burgard, Edward C, Uchic, Marie E, McDonald, Heath A, Niforatos, Wende, Faltynek, Connie R, Lynch, Kevin J, Jarvis, Michael F
Published in British journal of pharmacology (30.01.2009)
Published in British journal of pharmacology (30.01.2009)
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Development and validation of a medium-throughput electrophysiological assay for KCNQ2/3 channel openers using QPatch HT
Zhang, Xu-Feng, Zhang, Di, Surowy, Carol S, Yao, Betty, Jarvis, Michael F, McGaraughty, Steve, Neelands, Torben R
Published in Assay and drug development technologies (01.02.2013)
Published in Assay and drug development technologies (01.02.2013)
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Comparative analysis of inactivated-state block of N-type (Cav2.2) calcium channels
Vortherms, Timothy A., Swensen, Andrew M., Niforatos, Wende, Limberis, James T., Neelands, Torben R., Janis, Richard S., Thimmapaya, Rama, Donnelly-Roberts, Diana L., Namovic, Marian T., Zhang, Di, Brent Putman, C., Martin, Ruth L., Surowy, Carol S., Jarvis, Michael F., Scott, Victoria E.
Published in Inflammation research (01.07.2011)
Published in Inflammation research (01.07.2011)
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Journal Article
Comparative analysis of inactivated-state block of N-type (Ca(v)2.2) calcium channels
Vortherms, Timothy A, Swensen, Andrew M, Niforatos, Wende, Limberis, James T, Neelands, Torben R, Janis, Richard S, Thimmapaya, Rama, Donnelly-Roberts, Diana L, Namovic, Marian T, Zhang, Di, Brent Putman, C, Martin, Ruth L, Surowy, Carol S, Jarvis, Michael F, Scott, Victoria E
Published in Inflammation research (01.07.2011)
Published in Inflammation research (01.07.2011)
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Journal Article
Expression and purification of human TRPV1 in baculovirus-infected insect cells for structural studies
Korepanova, Alla, Pereda-Lopez, Ana, Solomon, Larry R., Walter, Karl A., Lake, Marc R., Bianchi, Bruce R., McDonald, Heath A., Neelands, Torben R., Shen, Jianwei, Matayoshi, Edmund D., Moreland, Robert B., Chiu, Mark L.
Published in Protein expression and purification (01.05.2009)
Published in Protein expression and purification (01.05.2009)
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