Mechanisms of cardiac ethanol toxicity and novel treatment options
Mustroph, Julian, Lebek, Simon, Maier, Lars S., Neef, Stefan
Published in Pharmacology & therapeutics (Oxford) (01.05.2019)
Published in Pharmacology & therapeutics (Oxford) (01.05.2019)
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Oxidized Ca2+/Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation
Purohit, Anil, Rokita, Adam G, Guan, Xiaoqun, Chen, Biyi, Koval, Olha M, Voigt, Niels, Neef, Stefan, Sowa, Thomas, Gao, Zhan, Luczak, Elizabeth D, Stefansdottir, Hrafnhildur, Behunin, Andrew C, Li, Na, El-Accaoui, Ramzi N, Yang, Baoli, Swaminathan, Paari Dominic, Weiss, Robert M, Wehrens, Xander H.T, Song, Long-Sheng, Dobrev, Dobromir, Maier, Lars S, Anderson, Mark E
Published in Circulation (New York, N.Y.) (15.10.2013)
Published in Circulation (New York, N.Y.) (15.10.2013)
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Crucial Role for Ca2+/Calmodulin-Dependent Protein Kinase-II in Regulating Diastolic Stress of Normal and Failing Hearts via Titin Phosphorylation
Hamdani, Nazha, Krysiak, Judith, Kreusser, Michael M, Neef, Stefan, dos Remedios, Cristobal G, Maier, Lars S, Krüger, Markus, Backs, Johannes, Linke, Wolfgang A
Published in Circulation research (15.02.2013)
Published in Circulation research (15.02.2013)
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Generation of Functional Murine Cardiac Myocytes From Induced Pluripotent Stem Cells
MAURITZ, Christina, SCHWANKE, Kristin, HASENFUSS, Gerd, MARTIN, Ulrich, REPPEL, Michael, NEEF, Stefan, KATSIRNTAKI, Katherina, MAIER, Lars S, NGUEMO, Filomain, MENKE, Sandra, HAUSTEIN, Moritz, HESCHELER, Juergen
Published in Circulation (New York, N.Y.) (29.07.2008)
Published in Circulation (New York, N.Y.) (29.07.2008)
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Ca2+/Calmodulin-Dependent Protein Kinase II and Protein Kinase A Differentially Regulate Sarcoplasmic Reticulum Ca2+ Leak in Human Cardiac Pathology
Fischer, Thomas H., Herting, Jonas, Tirilomis, Theodor, Renner, André, Neef, Stefan, Toischer, Karl, Ellenberger, David, Förster, Anna, Schmitto, Jan D., Gummert, Jan, Schöndube, Friedrich A., Hasenfuss, Gerd, Maier, Lars S., Sossalla, Samuel
Published in Circulation (New York, N.Y.) (27.08.2013)
Published in Circulation (New York, N.Y.) (27.08.2013)
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Inhibition of Elevated Ca2+/Calmodulin-Dependent Protein Kinase II Improves Contractility in Human Failing Myocardium
Sossalla, Samuel, Fluschnik, Nina, Schotola, Hanna, Ort, Katharina R, Neef, Stefan, Schulte, Timo, Wittköpper, Katrin, Renner, André, Schmitto, Jan D, Gummert, Jan, El-Armouche, Ali, Hasenfuss, Gerd, Maier, Lars S
Published in Circulation research (29.10.2010)
Published in Circulation research (29.10.2010)
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δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload
Backs, Johannes, Backs, Thea, Neef, Stefan, Kreusser, Michael M, Lehmann, Lorenz H, Patrick, David M, Grueter, Chad E, Qi, Xiaoxia, Richardson, James A, Hill, Joseph A, Katus, Hugo A, Bassel-Duby, Rhonda, Maier, Lars S, Olson, Eric N
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2009)
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Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure
Sag, Can M, Wadsack, Daniel P, Khabbazzadeh, Sepideh, Abesser, Marco, Grefe, Clemens, Neumann, Kay, Opiela, Marie-Kristin, Backs, Johannes, Olson, Eric N, Brown, Joan Heller, Neef, Stefan, Maier, Sebastian K G, Maier, Lars S
Published in Circulation. Heart failure (01.11.2009)
Published in Circulation. Heart failure (01.11.2009)
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Mitogen-Activated Protein Kinase-Activated Protein Kinases 2 and 3 Regulate SERCA2a Expression and Fiber Type Composition To Modulate Skeletal Muscle and Cardiomyocyte Function
Scharf, Madeleine, Neef, Stefan, Freund, Robert, Geers-Knörr, Cornelia, Franz-Wachtel, Mirita, Brandis, Almuth, Krone, Dorothee, Schneider, Heike, Groos, Stephanie, Menon, Manoj B., Chang, Kin-Chow, Kraft, Theresia, Meissner, Joachim D., Boheler, Kenneth R., Maier, Lars S., Gaestel, Matthias, Scheibe, Renate J.
Published in Molecular and Cellular Biology (01.07.2013)
Published in Molecular and Cellular Biology (01.07.2013)
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Ca2+/calmodulin‐dependent kinase IIδC‐induced chronic heart failure does not depend on sarcoplasmic reticulum Ca2+ leak
Dewenter, Matthias, Seitz, Tilmann, Steinbrecher, Julia H., Westenbrink, B. Daan, Ling, Haiyun, Lehnart, Stephan E., Wehrens, Xander H.T., Backs, Johannes, Brown, Joan Heller, Maier, Lars S., Neef, Stefan
Published in ESC Heart Failure (01.08.2024)
Published in ESC Heart Failure (01.08.2024)
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A Pilot Trial to Compare the Long-Term Efficacy of Pulmonary Vein Isolation with High-Power Short-Duration Radiofrequency Versus Laser Energy with Rapid Ablation Mode
Schildt, Sönke, Fredersdorf, Sabine, Jungbauer, Carsten G, Hauck, Christian, Tarnowski, Daniel, Debl, Kurt, Neef, Stefan, Schach, Christian, Sossalla, Samuel, Maier, Lars S, Üçer, Ekrem
Published in Journal of cardiovascular development and disease (23.02.2023)
Published in Journal of cardiovascular development and disease (23.02.2023)
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The oral Ca/calmodulin‐dependent kinase II inhibitor RA608 improves contractile function and prevents arrhythmias in heart failure
Mustroph, Julian, Drzymalski, Marzena, Baier, Maria, Pabel, Steffen, Biedermann, Alexander, Memmel, Bernadette, Durczok, Melanie, Neef, Stefan, Sag, Can Martin, Floerchinger, Bernhard, Rupprecht, Leopold, Schmid, Christof, Zausig, York, Bégis, Guillaume, Briand, Veronique, Ozoux, Marie‐Laure, Tamarelle, Dorothee, Ballet, Veronique, Janiak, Philip, Beauverger, Philippe, Maier, Lars S., Wagner, Stefan
Published in ESC Heart Failure (01.10.2020)
Published in ESC Heart Failure (01.10.2020)
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Patient delay and benefit of timely reperfusion in ST-segment elevation myocardial infarction
Scholz, Karl Heinrich, Meyer, Thomas, Lengenfelder, Björn, Vahlhaus, Christian, Tongers, Jörn, Schnupp, Steffen, Burckhard, Rainer, von Beckerath, Nicolas, Grusnick, Hans-Martin, Jeron, Andreas, Winter, Klaus Dieter, Maier, Sebastian K G, Danner, Michael, vom Dahl, Jürgen, Neef, Stefan, Stefanow, Stefan, Friede, Tim
Published in Open heart (01.05.2021)
Published in Open heart (01.05.2021)
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Overexpression of CaMKIIδc in RyR2R4496C+/− Knock-In Mice Leads to Altered Intracellular Ca2+ Handling and Increased Mortality
Dybkova, Nataliya, PhD, Sedej, Simon, PhD, Napolitano, Carlo, MD, PhD, Neef, Stefan, MD, Rokita, Adam G., MD, Hünlich, Mark, MD, Brown, Joan Heller, PhD, Kockskämper, Jens, PhD, Priori, Silvia G., MD, PhD, Pieske, Burkert, MD, Maier, Lars S., MD
Published in Journal of the American College of Cardiology (25.01.2011)
Published in Journal of the American College of Cardiology (25.01.2011)
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CaMKII as a target for arrhythmia suppression
Mustroph, Julian, Neef, Stefan, Maier, Lars S
Published in Pharmacology & therapeutics (Oxford) (01.08.2017)
Published in Pharmacology & therapeutics (Oxford) (01.08.2017)
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Improvement of cardiomyocyte function by a novel pyrimidine-based CaMKII-inhibitor
Neef, Stefan, Steffens, Alexander, Pellicena, Patricia, Mustroph, Julian, Lebek, Simon, Ort, Katharina R., Schulman, Howard, Maier, Lars S.
Published in Journal of molecular and cellular cardiology (01.02.2018)
Published in Journal of molecular and cellular cardiology (01.02.2018)
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CaMKII-Dependent Diastolic SR Ca2+ Leak and Elevated Diastolic Ca2+ Levels in Right Atrial Myocardium of Patients With Atrial Fibrillation
Neef, Stefan, Dybkova, Nataliya, Sossalla, Samuel, Ort, Katharina R, Fluschnik, Nina, Neumann, Kay, Seipelt, Ralf, Schöndube, Friedrich A, Hasenfuss, Gerd, Maier, Lars S
Published in Circulation research (02.04.2010)
Published in Circulation research (02.04.2010)
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Journal Article
Ethanol-Induced Atrial Fibrillation Results From Late I Na and Can Be Prevented by Ranolazine
Mustroph, Julian, Baier, Maria J., Unsin, Denise, Provaznik, Zdenek, Kozakov, Kostiantyn, Lebek, Simon, Tarnowski, Daniel, Schildt, Sönke, Voigt, Niels, Wagner, Stefan, Maier, Lars S., Neef, Stefan
Published in Circulation (New York, N.Y.) (22.08.2023)
Published in Circulation (New York, N.Y.) (22.08.2023)
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