Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancer
Hammerl, Dora, Martens, John W. M., Timmermans, Mieke, Smid, Marcel, Trapman-Jansen, Anita M., Foekens, Renée, Isaeva, Olga I., Voorwerk, Leonie, Balcioglu, Hayri E., Wijers, Rebecca, Nederlof, Iris, Salgado, Roberto, Horlings, Hugo, Kok, Marleen, Debets, Reno
Published in Nature communications (27.09.2021)
Published in Nature communications (27.09.2021)
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Journal Article
Comprehensive evaluation of methods to assess overall and cell-specific immune infiltrates in breast cancer
Nederlof, Iris, De Bortoli, Davide, Bareche, Yacine, Nguyen, Bastien, de Maaker, Michiel, Hooijer, Gerrit K J, Buisseret, Laurence, Kok, Marleen, Smid, Marcel, Van den Eynden, Gert G G M, Brinkman, Arie B, Hudecek, Jan, Koster, Jan, Sotiriou, Christos, Larsimont, Denis, Martens, John W M, van de Vijver, Marc J, Horlings, Hugo M, Salgado, Roberto, Biganzoli, Elia, Desmedt, Christine
Published in Breast cancer research : BCR (26.12.2019)
Published in Breast cancer research : BCR (26.12.2019)
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Journal Article
Increased HLA-G Expression in Term Placenta of Women with a History of Recurrent Miscarriage Despite Their Genetic Predisposition to Decreased HLA-G Levels
Craenmehr, Moniek H C, Nederlof, Iris, Cao, Milo, Drabbels, Jos J M, Spruyt-Gerritse, Marijke J, Anholts, Jacqueline D H, Kapsenberg, Hanneke M, Stegehuis, Janine A, van der Keur, Carin, Fasse, Esther, Haasnoot, Geert W, van der Hoorn, Marie-Louise P, Claas, Frans H J, Heidt, Sebastiaan, Eikmans, Michael
Published in International journal of molecular sciences (01.02.2019)
Published in International journal of molecular sciences (01.02.2019)
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Journal Article
Recognizing a Non‐classical Telomeropathy before Hematopoietic Stem Cell Transplantation in Pediatric Patients: A Case Series
Nederlof, Iris, Lindemans, Caroline A., Bierings, Marc B., Mohseny, Alexander B., Bresters, Dorine, Bartels, Marije
Published in HemaSphere (01.08.2019)
Published in HemaSphere (01.08.2019)
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Journal Article
DeepSMILE: Contrastive self-supervised pre-training benefits MSI and HRD classification directly from H&E whole-slide images in colorectal and breast cancer
Schirris, Yoni, Gavves, Efstratios, Nederlof, Iris, Horlings, Hugo Mark, Teuwen, Jonas
Published in Medical image analysis (01.07.2022)
Published in Medical image analysis (01.07.2022)
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Journal Article
Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial
Voorwerk, Leonie, Slagter, Maarten, Horlings, Hugo M., Sikorska, Karolina, van de Vijver, Koen K., de Maaker, Michiel, Nederlof, Iris, Kluin, Roelof J. C., Warren, Sarah, Ong, SuFey, Wiersma, Terry G., Russell, Nicola S., Lalezari, Ferry, Schouten, Philip C., Bakker, Noor A. M., Ketelaars, Steven L. C., Peters, Dennis, Lange, Charlotte A. H., van Werkhoven, Erik, van Tinteren, Harm, Mandjes, Ingrid A. M., Kemper, Inge, Onderwater, Suzanne, Chalabi, Myriam, Wilgenhof, Sofie, Haanen, John B. A. G., Salgado, Roberto, de Visser, Karin E., Sonke, Gabe S., Wessels, Lodewyk F. A., Linn, Sabine C., Schumacher, Ton N., Blank, Christian U., Kok, Marleen
Published in Nature medicine (01.06.2019)
Published in Nature medicine (01.06.2019)
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Journal Article
Tipping the balance: inhibitory checkpoints in intestinal homeostasis
Joosse, Maria E., Nederlof, Iris, Walker, Lucy S. K., Samsom, Janneke N.
Published in Mucosal immunology (2019)
Published in Mucosal immunology (2019)
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Journal Article
Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial
Nederlof, Iris, Isaeva, Olga I., de Graaf, Manon, Gielen, Robbert C. A. M., Bakker, Noor A. M., Rolfes, Adrianne L., Garner, Hannah, Boeckx, Bram, Traets, Joleen J. H., Mandjes, Ingrid A. M., de Maaker, Michiel, van Brussel, Thomas, Chelushkin, Maksim, Champanhet, Elisa, Lopez-Yurda, Marta, van de Vijver, Koen, van den Berg, José G., Hofland, Ingrid, Klioueva, Natasja, Mann, Ritse M., Loo, Claudette E., van Duijnhoven, Frederieke H., Skinner, Victoria, Luykx, Sylvia, Kerver, Emile, Kalashnikova, Ekaterina, van Dongen, Marloes G. J., Sonke, Gabe S., Linn, Sabine C., Blank, Christian U., de Visser, Karin E., Salgado, Roberto, Wessels, Lodewyk F. A., Drukker, Caroline A., Schumacher, Ton N., Horlings, Hugo M., Lambrechts, Diether, Kok, Marleen
Published in Nature medicine (01.11.2024)
Published in Nature medicine (01.11.2024)
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Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments
Kester, Lennart, Seinstra, Danielle, van Rossum, Annelot G J, Vennin, Claire, Hoogstraat, Marlous, van der Velden, Daphne, Opdam, Mark, van Werkhoven, Erik, Hahn, Kerstin, Nederlof, Iris, Lips, Ester H, Mandjes, Ingrid A M, van Leeuwen-Stok, A Elise, Canisius, Sander, van Tinteren, Harm, Imholz, Alex L T, Portielje, Johanneke E A, Bos, Monique E M M, Bakker, Sandra D, Rutgers, Emiel J, Horlings, Hugo M, Wesseling, Jelle, Voest, Emile E, Wessels, Lodewyk F A, Kok, Marleen, Oosterkamp, Hendrika M, van Oudenaarden, Alexander, Linn, Sabine C, van Rheenen, Jacco
Published in Clinical cancer research (01.03.2022)
Published in Clinical cancer research (01.03.2022)
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Journal Article
Interobserver Agreement of PD-L1/SP142 Immunohistochemistry and Tumor-Infiltrating Lymphocytes (TILs) in Distant Metastases of Triple-Negative Breast Cancer: A Proof-of-Concept Study. A Report on Behalf of the International Immuno-Oncology Biomarker Working Group
Van Bockstal, Mieke R, Cooks, Maxine, Nederlof, Iris, Brinkhuis, Mariël, Dutman, Annemiek, Koopmans, Monique, Kooreman, Loes, van der Vegt, Bert, Verhoog, Leon, Vreuls, Celine, Westenend, Pieter, Kok, Marleen, van Diest, Paul J, Nauwelaers, Inne, Laudus, Nele, Denkert, Carsten, Rimm, David, Siziopikou, Kalliopi P, Ely, Scott, Zardavas, Dimitrios, Roberts, Mustimbo, Floris, Giuseppe, Hartman, Johan, Acs, Balazs, Peeters, Dieter, Bartlett, John M S, Dequeker, Els, Salgado, Roberto, Giudici, Fabiola, Michiels, Stefan, Horlings, Hugo, van Deurzen, Carolien H M
Published in Cancers (29.09.2021)
Published in Cancers (29.09.2021)
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Journal Article
Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial
Voorwerk, Leonie, Slagter, Maarten, Horlings, Hugo M., Sikorska, Karolina, van de Vijver, Koen K., de Maaker, Michiel, Nederlof, Iris, Kluin, Roelof J. C., Warren, Sarah, Ong, SuFey, Wiersma, Terry G., Russell, Nicola S., Lalezari, Ferry, Schouten, Philip C., Bakker, Noor A. M., Ketelaars, Steven L. C., Peters, Dennis, Lange, Charlotte A. H., van Werkhoven, Erik, van Tinteren, Harm, Mandjes, Ingrid A. M., Kemper, Inge, Onderwater, Suzanne, Chalabi, Myriam, Wilgenhof, Sofie, Haanen, John B. A. G., Salgado, Roberto, de Visser, Karin E., Sonke, Gabe S., Wessels, Lodewyk F. A., Linn, Sabine C., Schumacher, Ton N., Blank, Christian U., Kok, Marleen
Published in Nature medicine (01.07.2019)
Published in Nature medicine (01.07.2019)
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Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials
Hudeček, Jan, Voorwerk, Leonie, van Seijen, Maartje, Nederlof, Iris, de Maaker, Michiel, van den Berg, Jose, van de Vijver, Koen K, Sikorska, Karolina, Adams, Sylvia, Demaria, Sandra, Viale, Giuseppe, Nielsen, Torsten O, Badve, Sunil S, Michiels, Stefan, Symmans, William Fraser, Sotiriou, Christos, Rimm, David L, Hewitt, Stephen M, Denkert, Carsten, Loibl, Sibylle, Loi, Sherene, Bartlett, John M S, Pruneri, Giancarlo, Dillon, Deborah A, Cheang, Maggie C U, Tutt, Andrew, Hall, Jacqueline A, Kos, Zuzana, Salgado, Roberto, Kok, Marleen, Horlings, Hugo M
Published in NPJ breast cancer (12.05.2020)
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Published in NPJ breast cancer (12.05.2020)
Journal Article
DeepSMILE: Contrastive self-supervised pre-training benefits MSI and HRD classification directly from H&E whole-slide images in colorectal and breast cancer
Schirris, Yoni, Gavves, Efstratios, Nederlof, Iris, Horlings, Hugo Mark, Teuwen, Jonas
Published in arXiv.org (28.06.2023)
Published in arXiv.org (28.06.2023)
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Risk Factors for Severe Acute Graft-versus-Host Disease in Donor Graft Composition
Stikvoort, Arwen, Gaballa, Ahmed, Solders, Martin, Nederlof, Iris, Önfelt, Björn, Sundberg, Berit, Remberger, Mats, Sundin, Mikael, Mattsson, Jonas, Uhlin, Michael
Published in Biology of blood and marrow transplantation (01.03.2018)
Published in Biology of blood and marrow transplantation (01.03.2018)
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Automated classification of cellular expression in multiplexed imaging data with Nimbus
Rumberger, J Lorenz, Greenwald, Noah F, Ranek, Jolene S, Boonrat, Potchara, Walker, Cameron, Franzen, Jannik, Varra, Sricharan Reddy, Kong, Alex, Sowers, Cameron, Liu, Candace C, Averbukh, Inna, Piyadasa, Hadeesha, Vanguri, Rami, Nederlof, Iris, Wang, Xuefei Julie, Van Valen, David, Kok, Marleen, Hollmann, Travis J, Kainmueller, Dagmar, Angelo, Michael
Published in bioRxiv (03.06.2024)
Published in bioRxiv (03.06.2024)
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