Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens
Nédélec, Yohann, Sanz, Joaquín, Baharian, Golshid, Szpiech, Zachary A., Pacis, Alain, Dumaine, Anne, Grenier, Jean-Christophe, Freiman, Andrew, Sams, Aaron J., Hebert, Steven, Pagé Sabourin, Ariane, Luca, Francesca, Blekhman, Ran, Hernandez, Ryan D., Pique-Regi, Roger, Tung, Jenny, Yotova, Vania, Barreiro, Luis B.
Published in Cell (20.10.2016)
Published in Cell (20.10.2016)
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Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations
Kim-Hellmuth, Sarah, Bechheim, Matthias, Pütz, Benno, Mohammadi, Pejman, Nédélec, Yohann, Giangreco, Nicholas, Becker, Jessica, Kaiser, Vera, Fricker, Nadine, Beier, Esther, Boor, Peter, Castel, Stephane E, Nöthen, Markus M, Barreiro, Luis B, Pickrell, Joseph K, Müller-Myhsok, Bertram, Lappalainen, Tuuli, Schumacher, Johannes, Hornung, Veit
Published in Nature communications (16.08.2017)
Published in Nature communications (16.08.2017)
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Adaptively introgressed Neandertal haplotype at the OAS locus functionally impacts innate immune responses in humans
Sams, Aaron J, Dumaine, Anne, Nédélec, Yohann, Yotova, Vania, Alfieri, Carolina, Tanner, Jerome E, Messer, Philipp W, Barreiro, Luis B
Published in Genome Biology (29.11.2016)
Published in Genome Biology (29.11.2016)
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Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection
Pai, Athma A, Baharian, Golshid, Pagé Sabourin, Ariane, Brinkworth, Jessica F, Nédélec, Yohann, Foley, Joseph W, Grenier, Jean-Christophe, Siddle, Katherine J, Dumaine, Anne, Yotova, Vania, Johnson, Zachary P, Lanford, Robert E, Burge, Christopher B, Barreiro, Luis B
Published in PLoS genetics (30.09.2016)
Published in PLoS genetics (30.09.2016)
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Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers
Perry, George H, Foll, Matthieu, Grenier, Jean-Christophe, Patin, Etienne, Nédélec, Yohann, Pacis, Alain, Barakatt, Maxime, Gravel, Simon, Zhou, Xiang, Nsobya, Sam L, Excoffier, Laurent, Quintana-Murci, Lluis, Dominy, Nathaniel J, Barreiro, Luis B
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2014)
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Annexin1 regulates DC efferocytosis and cross-presentation during Mycobacterium tuberculosis infection
Tzelepis, Fanny, Verway, Mark, Daoud, Jamal, Gillard, Joshua, Hassani-Ardakani, Kimya, Dunn, Jonathan, Downey, Jeffrey, Gentile, Marilena Elena, Jaworska, Joanna, Sanchez, Anthony Michel Jean, Nédélec, Yohann, Vali, Hojatollah, Tabrizian, Maryam, Kristof, Arnold Scott, King, Irah Luther, Barreiro, Luis Bruno, Divangahi, Maziar
Published in The Journal of clinical investigation (01.02.2015)
Published in The Journal of clinical investigation (01.02.2015)
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Deciphering the genetic control of gene expression following Mycobacterium leprae antigen stimulation
Manry, Jérémy, Nédélec, Yohann, Fava, Vinicius M, Cobat, Aurélie, Orlova, Marianna, Thuc, Nguyen Van, Thai, Vu Hong, Laval, Guillaume, Barreiro, Luis B, Schurr, Erwin
Published in PLoS genetics (01.08.2017)
Published in PLoS genetics (01.08.2017)
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A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection
Siddle, Katherine J, Deschamps, Matthieu, Tailleux, Ludovic, Nédélec, Yohann, Pothlichet, Julien, Lugo-Villarino, Geanncarlo, Libri, Valentina, Gicquel, Brigitte, Neyrolles, Olivier, Laval, Guillaume, Patin, Etienne, Barreiro, Luis B, Quintana-Murci, Lluís
Published in Genome research (01.05.2014)
Published in Genome research (01.05.2014)
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Gene set signature of reversal reaction type I in leprosy patients
Orlova, Marianna, Cobat, Aurélie, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Van Thuc, Nguyen, Spencer, John, Nédélec, Yohann, Barreiro, Luis, Thai, Vu Hong, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin
Published in PLoS genetics (01.07.2013)
Published in PLoS genetics (01.07.2013)
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Quantitative trait loci (QTL) study identifies novel genomic regions associated to Chiari-like malformation in Griffon Bruxellois dogs
Lemay, Philippe, Knowler, Susan P, Bouasker, Samir, Nédélec, Yohann, Platt, Simon, Freeman, Courtenay, Child, Georgina, Barreiro, Luis B, Rouleau, Guy A, Rusbridge, Clare, Kibar, Zoha
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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Gene Set Signature of Reversal Reaction Type I in Leprosy Patients: e1003624
Orlova, Marianna, Cobat, Aurélie, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Thuc, Nguyen Van, Spencer, John, Nédélec, Yohann, Barreiro, Luis, Thai, Vu Hong, Abel, Laurent, Alcaïs, Alexandre, Schurr, Erwin
Published in PLoS genetics (01.07.2013)
Published in PLoS genetics (01.07.2013)
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Gene set signature of reversal reaction type 1 in leprosy patients
Orlova, Marianna, Cobat, Aurelie, Huong, Nguyen Thu, Ba, Nguyen Ngoc, Van Thuc, Nguyen, Spencer, John, Nedelec, Yohann, Barreiro, Luis, Thai, Vu Hong, Abel, Laurent, Alcais, Alexandre, Schurr, Erwin
Published in PLoS genetics (01.07.2013)
Published in PLoS genetics (01.07.2013)
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Quantitative Trait Loci (QTL) Study Identifies Novel Genomic Regions Associated to Chiari-Like Malformation in Griffon Bruxellois Dogs: e89816
Lemay, Philippe, Knowler, Susan P, Bouasker, Samir, Nedelec, Yohann, Platt, Simon, Freeman, Courtenay, Child, Georgina, Barreiro, Luis B, Rouleau, Guy A, Rusbridge, Clare
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
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