Specific Inhibition of Hepatic Lactate Dehydrogenase Reduces Oxalate Production in Mouse Models of Primary Hyperoxaluria
Lai, Chengjung, Pursell, Natalie, Gierut, Jessica, Saxena, Utsav, Zhou, Wei, Dills, Michael, Diwanji, Rohan, Dutta, Chaitali, Koser, Martin, Nazef, Naim, Storr, Rachel, Kim, Boyoung, Martin-Higueras, Cristina, Salido, Eduardo, Wang, Weimin, Abrams, Marc, Dudek, Henryk, Brown, Bob D.
Published in Molecular therapy (01.08.2018)
Published in Molecular therapy (01.08.2018)
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A General Technique To Rank Protein−Ligand Binding Affinities and Determine Allosteric versus Direct Binding Site Competition in Compound Mixtures
Annis, D. Allen, Nazef, Naim, Chuang, Cheng-Chi, Scott, Margaret Porter, Nash, Huw M
Published in Journal of the American Chemical Society (01.12.2004)
Published in Journal of the American Chemical Society (01.12.2004)
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The discovery of 6-amino nicotinamides as potent and selective histone deacetylase inhibitors
Hamblett, Christopher L., Methot, Joey L., Mampreian, Dawn M., Sloman, David L., Stanton, Matthew G., Kral, Astrid M., Fleming, Judith C., Cruz, Jonathan C., Chenard, Melissa, Ozerova, Nicole, Hitz, Anna M., Wang, Hongmei, Deshmukh, Sujal V., Nazef, Naim, Harsch, Andreas, Hughes, Bethany, Dahlberg, William K., Szewczak, Alex A., Middleton, Richard E., Mosley, Ralph T., Secrist, J. Paul, Miller, Thomas A.
Published in Bioorganic & medicinal chemistry letters (01.10.2007)
Published in Bioorganic & medicinal chemistry letters (01.10.2007)
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Inhibitors of the lipid phosphatase SHIP2 discovered by high-throughput affinity selection-mass spectrometry screening of combinatorial libraries
Annis, D Allen, Cheng, Cliff C, Chuang, Cheng-Chi, McCarter, John D, Nash, Huw M, Nazef, Naim, Rowe, Todd, Kurzeja, Robert J M, Shipps, Jr, Gerald W
Published in Combinatorial chemistry & high throughput screening (01.09.2009)
Published in Combinatorial chemistry & high throughput screening (01.09.2009)
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Inhibition of Glycolate Oxidase With Dicer-substrate siRNA Reduces Calcium Oxalate Deposition in a Mouse Model of Primary Hyperoxaluria Type 1
Dutta, Chaitali, Avitahl-Curtis, Nicole, Pursell, Natalie, Larsson Cohen, Marita, Holmes, Benjamin, Diwanji, Rohan, Zhou, Wei, Apponi, Luciano, Koser, Martin, Ying, Bo, Chen, Dongyu, Shui, Xue, Saxena, Utsav, Cyr, Wendy A, Shah, Anee, Nazef, Naim, Wang, Weimin, Abrams, Marc, Dudek, Henryk, Salido, Eduardo, Brown, Bob D, Lai, Chengjung
Published in Molecular therapy (01.04.2016)
Published in Molecular therapy (01.04.2016)
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LDHA METHODS AND COMPOSITIONS FOR INHIBITING EXPRESSION OF LDHA
SAXENA UTSAV, PURSELL NATALIE, STORR RACHEL, BROWN BOB D, NAZEF NAIM, KIM BOYOUNG, DUDEK HENRYK T, LAI CHENG, WANG WEIMIN
Year of Publication 15.12.2023
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Year of Publication 15.12.2023
Patent
Discovery of a 5 H -Benzo[4,5]cyclohepta[1,2- b ]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer
Katz, Jason D., Jewell, James P., Guerin, David J., Lim, Jongwon, Dinsmore, Christopher J., Deshmukh, Sujal V., Pan, Bo-Sheng, Marshall, C. Gary, Lu, Wei, Altman, Michael D., Dahlberg, William K., Davis, Lenora, Falcone, Danielle, Gabarda, Ana E., Hang, Gaozhen, Hatch, Harold, Holmes, Rachael, Kunii, Kaiko, Lumb, Kevin J., Lutterbach, Bart, Mathvink, Robert, Nazef, Naim, Patel, Sangita B., Qu, Xianlu, Reilly, John F., Rickert, Keith W., Rosenstein, Craig, Soisson, Stephen M., Spencer, Kerrie B., Szewczak, Alexander A., Walker, Deborah, Wang, Wenxian, Young, Jonathan, Zeng, Qinwen
Published in Journal of medicinal chemistry (23.06.2011)
Published in Journal of medicinal chemistry (23.06.2011)
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Journal Article
Discovery of a 5H-Benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer
Katz, Jason D, Jewell, James P, Guerin, David J, Lim, Jongwon, Dinsmore, Christopher J, Deshmukh, Sujal V, Pan, Bo-Sheng, Marshall, C. Gary, Lu, Wei, Altman, Michael D, Dahlberg, William K, Davis, Lenora, Falcone, Danielle, Gabarda, Ana E, Hang, Gaozhen, Hatch, Harold, Holmes, Rachael, Kunii, Kaiko, Lumb, Kevin J, Lutterbach, Bart, Mathvink, Robert, Nazef, Naim, Patel, Sangita B, Qu, Xianlu, Reilly, John F, Rickert, Keith W, Rosenstein, Craig, Soisson, Stephen M, Spencer, Kerrie B, Szewczak, Alexander A, Walker, Deborah, Wang, Wenxian, Young, Jonathan, Zeng, Qinwen
Published in Journal of medicinal chemistry (23.06.2011)
Published in Journal of medicinal chemistry (23.06.2011)
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Journal Article
LDHA의 발현을 억제하기 위한 방법 및 조성물
SAXENA UTSAV, PURSELL NATALIE, STORR RACHEL, BROWN BOB D, NAZEF NAIM, KIM BOYOUNG, DUDEK HENRYK T, LAI CHENG, WANG WEIMIN
Year of Publication 01.07.2020
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Year of Publication 01.07.2020
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