Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells
Trigili, Chiara, Barasoain, Isabel, Sánchez-Murcia, Pedro A, Bargsten, Katja, Redondo-Horcajo, Mariano, Nogales, Aurora, Gardner, Nicola M, Meyer, Arndt, Naylor, Guy J, Gómez-Rubio, Elena, Gago, Federico, Steinmetz, Michel O, Paterson, Ian, Prota, Andrea E, Díaz, J. Fernando
Published in ACS omega (31.12.2016)
Published in ACS omega (31.12.2016)
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Journal Article
Leiodermatolide, a Potent Antimitotic Macrolide from the Marine Sponge Leiodermatium sp
Paterson, Ian, Dalby, Stephen M., Roberts, Jill C., Naylor, Guy J., Guzmán, Esther A., Isbrucker, Richard, Pitts, Tara P., Linley, Pat, Divlianska, Daniela, Reed, John K., Wright, Amy E.
Published in Angewandte Chemie (International ed.) (28.03.2011)
Published in Angewandte Chemie (International ed.) (28.03.2011)
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Journal Article
Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin
Paterson, Ian, Naylor, Guy J., Fujita, Takeshi, Guzman, Esther, Wright, Amy E.
Published in Chemical communications (Cambridge, England) (01.01.2010)
Published in Chemical communications (Cambridge, England) (01.01.2010)
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Journal Article
Total synthesis and biological evaluation of a series of macrocyclic hybrids and analogues of the antimitotic natural products dictyostatin, discodermolide, and taxol
Paterson, Ian, Naylor, Guy J, Gardner, Nicola M, Guzmán, Esther, Wright, Amy E
Published in Chemistry, an Asian journal (01.02.2011)
Published in Chemistry, an Asian journal (01.02.2011)
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Total synthesis of novel dictyostatin analogs and hybrids as microtubule-stabilizing anticancer agents
Paterson, Ian, Gardner, Nicola M., Naylor, Guy J.
Published in Pure and applied chemistry (01.01.2009)
Published in Pure and applied chemistry (01.01.2009)
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Journal Article
Leiodermatolide, a Potent Antimitotic Macrolide from the Marine Sponge Leiodermatium sp
Paterson, Ian, Dalby, Stephen M., Roberts, Jill C., Naylor, Guy J., Guzmán, Esther A., Isbrucker, Richard, Pitts, Tara P., Linley, Pat, Divlianska, Daniela, Reed, John K., Wright, Amy E.
Published in Angewandte Chemie (28.03.2011)
Published in Angewandte Chemie (28.03.2011)
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Journal Article
Leiodermatolide, a Potent Antimitotic Macrolide from the Marine Sponge Leiodermatium sp
Paterson, Ian, Dalby, Stephen M., Roberts, Jill C., Naylor, Guy J., Guzmán, Esther A., Isbrucker, Richard, Pitts, Tara P., Linley, Pat, Divlianska, Daniela, Reed, John K., Wright, Amy E.
Published in Angewandte Chemie (28.03.2011)
Published in Angewandte Chemie (28.03.2011)
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Journal Article
Total synthesis of (-)-dictyostatin, a microtubule-stabilising anticancer macrolide of marine sponge origin: 2009 Tetrahedron Prize for Creativity in Organic Chemistry: Adventures in Organic Synthesis: Steven V. Ley
PATERSON, Ian, BRITTON, Robert, DELGADO, Oscar, GARDNER, Nicola M, MEYER, Arndt, NAYLOR, Guy J, POULLENNEC, Karine G
Published in Tetrahedron (2010)
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Published in Tetrahedron (2010)
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ChemInform Abstract: Total Synthesis of a Library of Designed Hybrids of the Microtubule-Stabilizing Anticancer Agents Taxol, Discodermolide and Dictyostatin
Paterson, Ian, Naylor, Guy J., Fujita, Takeshi, Guzman, Esther, Wright, Amy E.
Published in ChemInform (11.05.2010)
Published in ChemInform (11.05.2010)
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