A myeloid-stromal niche and gp130 rescue in NOD2-driven Crohn's disease
Nayar, Shikha, Morrison, Joshua K, Giri, Mamta, Gettler, Kyle, Chuang, Ling-Shiang, Walker, Laura A, Ko, Huaibin M, Kenigsberg, Ephraim, Kugathasan, Subra, Merad, Miriam, Chu, Jaime, Cho, Judy H
Published in Nature (London) (13.05.2021)
Published in Nature (London) (13.05.2021)
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Journal Article
MPI depletion enhances O-GlcNAcylation of p53 and suppresses the Warburg effect
Shtraizent, Nataly, DeRossi, Charles, Nayar, Shikha, Sachidanandam, Ravi, Katz, Liora S, Prince, Adam, Koh, Anna P, Vincek, Adam, Hadas, Yoav, Hoshida, Yujin, Scott, Donald K, Eliyahu, Efrat, Freeze, Hudson H, Sadler, Kirsten C, Chu, Jaime
Published in eLife (23.06.2017)
Published in eLife (23.06.2017)
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Journal Article
Zebrafish modeling of intestinal injury, bacterial exposures and medications defines epithelial in vivo responses relevant to human inflammatory bowel disease
Chuang, Ling-Shiang, Morrison, Joshua, Hsu, Nai-Yun, Labrias, Philippe Ronel, Nayar, Shikha, Chen, Ernie, Villaverde, Nicole, Facey, Jody Ann, Boschetti, Gilles, Giri, Mamta, Castillo-Martin, Mireia, Thin, Tin Htwe, Sharma, Yashoda, Chu, Jaime, Cho, Judy H
Published in Disease models & mechanisms (01.08.2019)
Published in Disease models & mechanisms (01.08.2019)
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Journal Article
Single‐cell transcriptomics reveals conserved cell identities and fibrogenic phenotypes in zebrafish and human liver
Morrison, Joshua K., DeRossi, Charles, Alter, Isaac L., Nayar, Shikha, Giri, Mamta, Zhang, Chi, Cho, Judy H., Chu, Jaime
Published in Hepatology communications (01.07.2022)
Published in Hepatology communications (01.07.2022)
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Journal Article
Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy
Martin, Jerome C., Chang, Christie, Boschetti, Gilles, Ungaro, Ryan, Giri, Mamta, Grout, John A., Gettler, Kyle, Chuang, Ling-shiang, Nayar, Shikha, Greenstein, Alexander J., Dubinsky, Marla, Walker, Laura, Leader, Andrew, Fine, Jay S., Whitehurst, Charles E., Mbow, M Lamine, Kugathasan, Subra, Denson, Lee A., Hyams, Jeffrey S., Friedman, Joshua R., Desai, Prerak T., Ko, Huaibin M., Laface, Ilaria, Akturk, Guray, Schadt, Eric E., Salmon, Helene, Gnjatic, Sacha, Rahman, Adeeb H., Merad, Miriam, Cho, Judy H., Kenigsberg, Ephraim
Published in Cell (05.09.2019)
Published in Cell (05.09.2019)
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Journal Article
NOX1 is essential for TNFα-induced intestinal epithelial ROS secretion and inhibits M cell signatures
Hsu, Nai-Yun, Nayar, Shikha, Gettler, Kyle, Talware, Sayali, Giri, Mamta, Alter, Isaac, Argmann, Carmen, Sabic, Ksenija, Thin, Tin Htwe, Ko, Huai-Bin Mabel, Werner, Robert, Tastad, Christopher, Stappenbeck, Thaddeus, Azabdaftari, Aline, Uhlig, Holm H, Chuang, Ling-Shiang, Cho, Judy H
Published in Gut (01.04.2023)
Published in Gut (01.04.2023)
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Journal Article
Machine learning identifies novel blood protein predictors of penetrating and stricturing complications in newly diagnosed paediatric Crohn's disease
Ungaro, Ryan C., Hu, Liangyuan, Ji, Jiayi, Nayar, Shikha, Kugathasan, Subra, Denson, Lee A., Hyams, Jeffrey, Dubinsky, Marla C., Sands, Bruce E., Cho, Judy H.
Published in Alimentary pharmacology & therapeutics (01.01.2021)
Published in Alimentary pharmacology & therapeutics (01.01.2021)
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Journal Article
Inflamed Ulcerative Colitis Regions Associated With MRGPRX2-Mediated Mast Cell Degranulation and Cell Activation Modules, Defining a New Therapeutic Target
Chen, Ernie, Chuang, Ling-shiang, Giri, Mamta, Villaverde, Nicole, Hsu, Nai-yun, Sabic, Ksenija, Joshowitz, Sari, Gettler, Kyle, Nayar, Shikha, Chai, Zhi, Alter, Isaac L., Chasteau, Colleen C., Korie, Ujunwa M., Dzedzik, Siarhei, Thin, Tin Htwe, Jain, Aayushee, Moscati, Arden, Bongers, Gerardus, Duerr, Richard H., Silverberg, Mark S., Brant, Steven R., Rioux, John D., Peter, Inga, Schumm, L. Philip, Haritunians, Talin, McGovern, Dermot P., Itan, Yuval, Cho, Judy H.
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.04.2021)
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102: DISCOVERY AND VALIDATION OF A BLOOD PROTEIN PANEL ASSOCIATED WITH TUMOR NECROSIS FACTOR ANTAGONIST TREATMENT FAILURE IN RECENTLY DIAGNOSED CROHN'S DISEASE (CD) PATIENTS
Ungaro, Ryan C., Hu, Liangyuan, Ji, Jiayi, Nayar, Shikha, Kugathasan, Subra, Denson, Lee A., Hyams, Jeffrey S., Dubinsky, Marla, Leleiko, Neal S., Shapiro, Jason M., Shah, Samir A., Sands, Bruce E., Cho, Judy H.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2022)
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Journal Article
A Role for CXCR3 Ligands as Biomarkers of Post-Operative Crohn’s Disease Recurrence
Walshe, Margaret, Nayeri, Shadi, Ji, Jiayi, Hernandez-Rocha, Cristian, Sabic, Ksenija, Hu, Liangyuan, Giri, Mamta, Nayar, Shikha, Brant, Steven, McGovern, Dermot P B, Rioux, John D, Duerr, Richard H, Cho, Judy H, Schumm, Phil L, Lazarev, Mark, Silverberg, Mark S
Published in Journal of Crohn's and colitis (14.07.2022)
Published in Journal of Crohn's and colitis (14.07.2022)
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Journal Article
374 INFLAMED ULCERATIVE COLITIS REGIONS ASSOCIATED TO MRGPRX2-MEDIATED MAST CELL DEGRANULATION AND CELL ACTIVATION MODULES, DEFINING A NEW THERAPEUTIC TARGET
Chuang, Ling-shiang F., Chen, Ernie, Giri, Mamta, Villaverde, Nicole, Hsu, Nai-yun, Sabic, Ksenija, Joshowitz, Sari, Gettler, Kyle, Nayar, Shikha, Chai, Zhi, Alter, Isaac, Chasteau, Colleen, Korie, Ujunwa, Dzedzik, Siarhei, Thin, Tin Htwe, Jain, Aayushee, Moscati, Arden, Bongers, Gerold, Duerr, Richard H., Silverberg, Mark S., Brant, Steven R., Rioux, John D., Peter, Inga, Schumm, L. Philip, Haritunians, Talin, Mcgovern, Dermot P.B., Itan, Yuval, Cho, Judy H.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
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Journal Article
trappc11 is required for protein glycosylation in zebrafish and humans
DeRossi, Charles, Vacaru, Ana, Rafiq, Ruhina, Cinaroglu, Ayca, Imrie, Dru, Nayar, Shikha, Baryshnikova, Anastasia, Milev, Miroslav P, Stanga, Daniela, Kadakia, Dhara, Gao, Ningguo, Chu, Jaime, Freeze, Hudson H, Lehrman, Mark A, Sacher, Michael, Sadler, Kirsten C
Published in Molecular biology of the cell (15.04.2016)
Published in Molecular biology of the cell (15.04.2016)
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Journal Article
Inflamed ulcerative colitis regions associated to MRGPRX2-mediated mast cell degranulation and cell activation modules, defining a new therapeutic target
Chen, Ernie, Chuang, Ling-shiang, Giri, Mamta, Villaverde, Nicole, Hsu, Nai-yun, Sabic, Ksenija, Joshowitz, Sari, Gettler, Kyle, Nayar, Shikha, Chai, Zhi, Alter, Isaac L., Chasteau, Colleen C., Korie, Ujunwa M., Dzedzik, Siarhei, Thin, Tin Htwe, Jain, Aayushee, Moscati, Arden, Bongers, Gerardus, Duerr, Richard H., Silverberg, Mark S., Brant, Steven R., Rioux, John D., Peter, Inga, Schumm, L. Philip, Haritunians, Talin, McGovern, Dermot P., Itan, Yuval, Cho, Judy H.
Published in Gastroenterology (New York, N.Y. 1943) (06.01.2021)
Published in Gastroenterology (New York, N.Y. 1943) (06.01.2021)
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Journal Article
Single-cell analysis of Crohn's disease lesions identifies a pathogenic cellular module associated with resistance to anti TNF therapy
Jerome Christophe Martin, Boschetti, Gilles, Chang, Christie, Ungaro, Ryan, Giri, Mamta, Ling-Shiang Chuang, Nayar, Shikha, Greenstein, Alexander, Dubinsky, Marla, Walker, Laura, Leader, Andrew, Fine, Jay, Whitehurst, Charles, Mbow, Lamine, Kugathasan, Subra, Denson, Lee, Hyams, Jeffrey, Friedman, Joshua, Desai, Prerak, Ko, Mabel, Laface, Ilaria, Akturk, Guray, Schadt, Eric, Gnjatic, Sacha, Rahman, Adeeb, Merad, Miriam, Cho, Judy, Kenigsberg, Ephraim
Published in bioRxiv (20.12.2018)
Published in bioRxiv (20.12.2018)
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