Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1
Napper, Andrew D, Hixon, Jeffrey, McDonagh, Thomas, Keavey, Kenneth, Pons, Jean-Francois, Barker, Jonathan, Yau, Wei Tsung, Amouzegh, Patricia, Flegg, Adam, Hamelin, Estelle, Thomas, Russell J, Kates, Michael, Jones, Stephen, Navia, Manuel A, Saunders, Jeffrey O, DiStefano, Peter S, Curtis, Rory
Published in Journal of medicinal chemistry (15.12.2005)
Published in Journal of medicinal chemistry (15.12.2005)
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Journal Article
A novel dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of inflammatory diseases
Docherty, Callum Ah, Fernando, Anuruddika J, Rosli, Sarah, Lam, Maggie, Dolle, Roland E, Navia, Manuel A, Farquhar, Ronald, La France, Danny, Tate, Michelle D, Murphy, Christopher K, Rossi, Adriano G, Mansell, Ashley
Published in Clinical & translational immunology (01.01.2023)
Published in Clinical & translational immunology (01.01.2023)
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X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex
Griffith, James P, Kim, Joseph L, Kim, Eunice E, Sintchak, Michael D, Thomson, John A, Fitzgibbon, Matthew J, Fleming, Mark A, Caron, Paul R, Hsiao, Kathy, Navia, Manuel A
Published in Cell (11.08.1995)
Published in Cell (11.08.1995)
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Journal Article
A Chicken in Every Pot, Thanks to Sulfonamide Drugs
Navia, Manuel A., Drews, Jürgen
Published in Science (American Association for the Advancement of Science) (23.06.2000)
Published in Science (American Association for the Advancement of Science) (23.06.2000)
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Journal Article
Protein Crystals as Novel Microporous Materials
Vilenchik, Lev Z, Griffith, James P, St. Clair, Nancy, Navia, Manuel A, Margolin, Alexey L
Published in Journal of the American Chemical Society (13.05.1998)
Published in Journal of the American Chemical Society (13.05.1998)
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Journal Article
Protein Crystals as Novel Catalytic Materials
Margolin, Alexey L., Navia, Manuel A.
Published in Angewandte Chemie International Edition (18.06.2001)
Published in Angewandte Chemie International Edition (18.06.2001)
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Journal Article
Synthesis of Aspartame by Thermolysin: An X‑ray Structural Study
Birrane, Gabriel, Bhyravbhatla, Balaji, Navia, Manuel A
Published in ACS medicinal chemistry letters (12.06.2014)
Published in ACS medicinal chemistry letters (12.06.2014)
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Journal Article
A call to arms: Unifying the fight against resistance
Kaushansky, Alexis, Hedstrom, Lizbeth, Goldman, Aaron, Singh, Juswinder, Yang, Priscilla L, Rathod, Pradipsinh K, Cynamon, Michael, Wodarz, Dominik, Mahadevan, Daruka, Tomaras, Andrew, Navia, Manuel A, Schiffer, Celia A
Published in Science signaling (23.10.2018)
Published in Science signaling (23.10.2018)
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Journal Article
Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1
Napper, Andrew D, Hixon, Jeffrey, McDonagh, Thomas, Keavey, Kenneth, Pons, Jean-Francois, Barker, Jonathan, Yau, Wei Tsung, Amouzegh, Patricia, Flegg, Adam, Hamelin, Estelle, Thomas, Russell J, Kates, Michael, Jones, Stephen, Navia, Manuel A, Saunders, Jeffrey O, DiStefano, Peter S, Curtis, Rory
Published in Journal of medicinal chemistry (08.03.2007)
Published in Journal of medicinal chemistry (08.03.2007)
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Journal Article
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1
Navia, M A, Fitzgerald, P M, McKeever, B M, Leu, C T, Heimbach, J C, Herber, W K, Sigal, I S, Darke, P L, Springer, J P
Published in Nature (London) (16.02.1989)
Published in Nature (London) (16.02.1989)
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Journal Article
Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity
Longo, Kenneth A, Govek, Elizabeth K, Nolan, Anna, McDonagh, Thomas, Charoenthongtrakul, Soratree, Giuliana, Derek J, Morgan, Kristen, Hixon, Jeffrey, Zhou, Chaoseng, Kelder, Bruce, Kopchick, John J, Saunders, Jeffrey O, Navia, Manuel A, Curtis, Rory, DiStefano, Peter S, Geddes, Brad J
Published in The Journal of pharmacology and experimental therapeutics (01.10.2011)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2011)
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Journal Article
Cross-linked enzyme crystals as robust biocatalysts
St. Clair, Nancy L, Navia, Manuel A
Published in Journal of the American Chemical Society (01.08.1992)
Published in Journal of the American Chemical Society (01.08.1992)
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Journal Article
Structure and mechanism of interleukin-lβ converting enzyme
Wilson, Keith P, Black, Jo-Anne F, Thomson, John A, Kim, Eunice E, Griffith, James P, Navia, Manuel A, Murcko, Mark A, Chambers, Stephen P, Aldape, Robert A, Raybuck, Scott A, Livingston, David J
Published in Nature (London) (28.07.1994)
Published in Nature (London) (28.07.1994)
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Journal Article
뇌척수액 개선 방법 및 이를 위한 디바이스 및 시스템
EGGAN KEVIN, WATSON ALAN D, KALISH KEVIN, TSENG CHING HUA, DEPASQUA ANTHONY, GLICKSMAN MARCIE ANN, NAVIA MANUEL A, SIOPES WILLIAM, RICCARDI GIANNA, ROET KASPER
Year of Publication 27.01.2022
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Year of Publication 27.01.2022
Patent
Protein Crystal Growth in Microgravity
DeLucas, Lawrence J., Smith, Craig D., Smith, H. Wilson, Vijay-Kumar, Senadhi, Senadhi, Shobha E., Ealick, Steven E., Carter, Daniel C., Snyder, Robert S., Weber, Patricia C., Salemme, F. Raymond, Ohlendorf, D. H., Einspahr, H. M., Clancy, L. L., Navia, Manuel A., McKeever, Brian M., Nagabhushan, T. L., Nelson, George, McPherson, A., Koszelak, S., Taylor, G., Stammers, D., Powell, K., Darby, G., Bugg, Charles E.
Published in Science (American Association for the Advancement of Science) (03.11.1989)
Published in Science (American Association for the Advancement of Science) (03.11.1989)
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Journal Article
Inhibition of human leukocyte elastase. 2. Inhibition by substituted cephalosporin esters and amides
Finke, Paul E, Ashe, Bonnie M, Knight, Wilson B, Maycock, Alan L, Navia, Manuel A, Shah, Shrenik K, Thompson, Kevan R, Underwood, Dennis J, Weston, Hazel
Published in Journal of medicinal chemistry (01.09.1990)
Published in Journal of medicinal chemistry (01.09.1990)
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