Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells
Nalapareddy, Kodandaramireddy, Nattamai, Kalpana J., Kumar, Rupali S., Karns, Rebekah, Wikenheiser-Brokamp, Kathryn A., Sampson, Leesa L., Mahe, Maxime M., Sundaram, Nambirajan, Yacyshyn, Mary-Beth, Yacyshyn, Bruce, Helmrath, Michael A., Zheng, Yi, Geiger, Hartmut
Published in Cell reports (Cambridge) (14.03.2017)
Published in Cell reports (Cambridge) (14.03.2017)
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Journal Article
Repolarization of HSC attenuates HSCs failure in Shwachman-Diamond syndrome
Kumar, Sachin, Nattamai, Kalpana J, Hassan, Aishlin, Amoah, Amanda, Karns, Rebekah, Zhang, Cuiping, Liang, Ying, Shimamura, Akiko, Florian, M Carolina, Bissels, Ute, Luevano, Martha, Bosio, Andreas, Davies, Stella M, Mulaw, Medhanie, Geiger, Hartmut, Myers, Kasiani C
Published in Leukemia (01.06.2021)
Published in Leukemia (01.06.2021)
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Journal Article
Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity
Geiger, Hartmut, Pawar, Snehalata A, Kerschen, Edward J, Nattamai, Kalpana J, Hernandez, Irene, Liang, Hai Po H, Fernández, Jose Á, Cancelas, Jose A, Ryan, Marnie A, Kustikova, Olga, Schambach, Axel, Fu, Qiang, Wang, Junru, Fink, Louis M, Petersen, Karl-Uwe, Zhou, Daohong, Griffin, John H, Baum, Christopher, Weiler, Hartmut, Hauer-Jensen, Martin
Published in Nature medicine (01.07.2012)
Published in Nature medicine (01.07.2012)
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Journal Article
The lifespan quantitative trait locus gene Securin controls hematopoietic progenitor cell function
Brown, Andreas, Schuetz, Desiree, Han, Yang, Daria, Deidre, Nattamai, Kalpana J, Eiwen, Karina, Sakk, Vadim, Pospiech, Johannes, Saller, Thomas, van Zant, Gary, Wagner, Wolfgang, Geiger, Hartmut
Published in Haematologica (Roma) (01.02.2020)
Published in Haematologica (Roma) (01.02.2020)
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Journal Article
Aging alters the epigenetic asymmetry of HSC division
Florian, M Carolina, Klose, Markus, Sacma, Mehmet, Jablanovic, Jelena, Knudson, Luke, Nattamai, Kalpana J, Marka, Gina, Vollmer, Angelika, Soller, Karin, Sakk, Vadim, Cabezas-Wallscheid, Nina, Zheng, Yi, Mulaw, Medhanie A, Glauche, Ingmar, Geiger, Hartmut
Published in PLoS biology (20.09.2018)
Published in PLoS biology (20.09.2018)
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Journal Article
Increased hematopoietic stem cell mobilization in aged mice
Xing, Zhenlan, Ryan, Marnie A., Daria, Deidre, Nattamai, Kalpana J., Van Zant, Gary, Wang, Lei, Zheng, Yi, Geiger, Hartmut
Published in Blood (01.10.2006)
Published in Blood (01.10.2006)
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Journal Article
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing
Florian, Maria Carolina, Nattamai, Kalpana J, Dörr, Karin, Marka, Gina, Uberle, Bettina, Vas, Virag, Eckl, Christina, Andrä, Immanuel, Schiemann, Matthias, Oostendorp, Robert A J, Scharffetter-Kochanek, Karin, Kestler, Hans Armin, Zheng, Yi, Geiger, Hartmut
Published in Nature (London) (21.11.2013)
Published in Nature (London) (21.11.2013)
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Journal Article
Rejuvenation of the reconstitution potential and reversal of myeloid bias of aged HSCs upon pH treatment
Kumar, Sachin, Vassallo, Jeffrey D., Nattamai, Kalpana J., Hassan, Aishlin, Vollmer, Angelika, Karns, Rebekah, Sacma, Mehmet, Nemkov, Travis, D'Alessandro, Angelo, Geiger, Hartmut
Published in Aging cell (05.09.2024)
Published in Aging cell (05.09.2024)
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Journal Article
Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice
Florian, Maria Carolina, Leins, Hanna, Gobs, Michael, Han, Yang, Marka, Gina, Soller, Karin, Vollmer, Angelika, Sakk, Vadim, Nattamai, Kalpana J., Rayes, Ahmad, Zhao, Xueheng, Setchell, Kenneth, Mulaw, Medhanie, Wagner, Wolfgang, Zheng, Yi, Geiger, Hartmut
Published in Aging cell (01.09.2020)
Published in Aging cell (01.09.2020)
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Journal Article
pH regulates hematopoietic stem cell potential via polyamines
Kumar, Sachin, Vassallo, Jeffrey D, Nattamai, Kalpana J, Hassan, Aishlin, Karns, Rebekah, Vollmer, Angelika, Soller, Karin, Sakk, Vadim, Sacma, Mehmet, Nemkov, Travis, D'Alessandro, Angelo, Geiger, Hartmut
Published in EMBO reports (04.05.2023)
Published in EMBO reports (04.05.2023)
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Journal Article
TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells
Li, June, Sejas, Daniel P, Zhang, Xiaoling, Qiu, Yuhui, Nattamai, Kalpana J, Rani, Reena, Rathbun, Keaney R, Geiger, Hartmut, Williams, David A, Bagby, Grover C, Pang, Qishen
Published in The Journal of clinical investigation (01.11.2007)
Published in The Journal of clinical investigation (01.11.2007)
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Journal Article
Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization
Geiger, Hartmut, Ryan, Marnie A, Nattamai, Kalpana J, Xing, Ellen, Schleimer, David, Daria, Deidre, Sengupta, Amitava, Köhler, Anja, Liu, Wei, Gunzer, Matthias, Jansen, Michael, Ratner, Nancy, Le Cras, Timothy D, Waterstrat, Amanda, Van Zant, Gary, Cancelas, Jose A, Zheng, Yi
Published in Nature medicine (01.10.2010)
Published in Nature medicine (01.10.2010)
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Journal Article
Reduced adhesion of aged intestinal stem cells contributes to an accelerated clonal drift
Hageb, Ali, Thalheim, Torsten, Nattamai, Kalpana J, Möhrle, Bettina, Saçma, Mehmet, Sakk, Vadim, Thielecke, Lars, Cornils, Kerstin, Grandy, Carolin, Port, Fabian, Gottschalk, Kay-E, Mallm, Jan-Philipp, Glauche, Ingmar, Galle, Jörg, Mulaw, Medhanie A, Geiger, Hartmut
Published in Life science alliance (01.08.2022)
Published in Life science alliance (01.08.2022)
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Journal Article
Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity
Schultz, Jo El J, Glascock, Betty J, Witt, Sandra A, Nieman, Michelle L, Nattamai, Kalpana J, Liu, Lynne H, Lorenz, John N, Shull, Gary E, Kimball, Thomas R, Periasamy, Muthu
Published in American journal of physiology. Heart and circulatory physiology (01.03.2004)
Published in American journal of physiology. Heart and circulatory physiology (01.03.2004)
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Journal Article
Mutagenic potential of temozolomide in bone marrow cells in vivo
Geiger, Hartmut, Schleimer, David, Nattamai, Kalpana J., Dannenmann, Stefanie R., Davies, Stella M., Weiss, Brian D.
Published in Blood (01.04.2006)
Published in Blood (01.04.2006)
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Journal Article
Altered dose response to beta -agonists in SERCA1a-expressing hearts ex vivo and in vivo
Huke, Sabine, Prasad, Vikram, Nieman, Michelle L, Nattamai, Kalpana J, Grupp, Ingrid L, Lorenz, John N, Periasamy, Muthu
Published in American journal of physiology. Heart and circulatory physiology (01.09.2002)
Published in American journal of physiology. Heart and circulatory physiology (01.09.2002)
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Journal Article
Clonality and Mixed Mutational Signature in Aged Hematopoietic Stem Cells Via Single Cell Variant Analysis
Florian, Maria C, Nattamai, Kalpana J, Geiger, Hartmut, Mulaw, Medhanie A.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Pharmacological targeting of the thrombomodulin–protein C pathway mitigates radiation toxicity
Geiger, Hartmut, Pawar, Snehalata A, Kerschen, Edward J., Nattamai, Kalpana J., Hernandez, Irene, Liang, Hai Po, Fernández, Jose Á, Cancelas, Jose A., Ryan, Marnie A., Kustikova, Olga, Schambach, Axel, Fu, Qiang, Wang, Junru, Fink, Louis M., Petersen, Karl-Uwe, Zhou, Daohong, Griffin, John H., Baum, Christopher, Weiler, Hartmut, Hauer-Jensen, Martin
Published in Nature medicine (01.07.2012)
Published in Nature medicine (01.07.2012)
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Journal Article