Phase III Randomized Clinical Trial Comparing Tremelimumab With Standard-of-Care Chemotherapy in Patients With Advanced Melanoma
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Published in Journal of clinical oncology (10.02.2013)
Published in Journal of clinical oncology (10.02.2013)
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Published in The lancet oncology (01.05.2014)
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Regorafenib for patients with previously untreated metastatic or unresectable renal-cell carcinoma: a single-group phase 2 trial
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Published in The lancet oncology (01.10.2012)
Published in The lancet oncology (01.10.2012)
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PRISM protocol: a randomised phase II trial of nivolumab in combination with alternatively scheduled ipilimumab in first-line treatment of patients with advanced or metastatic renal cell carcinoma
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Published in BMC cancer (14.11.2019)
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Spartalizumab or placebo in combination with dabrafenib and trametinib in patients with BRAF V600-mutant melanoma: exploratory biomarker analyses from a randomized phase 3 trial (COMBI-i)
Tawbi, Hussein A, Robert, Caroline, Brase, Jan C, Gusenleitner, Daniel, Gasal, Eduard, Garrett, James, Savchenko, Alexander, Görgün, Güllü, Flaherty, Keith T, Ribas, Antoni, Dummer, Reinhard, Schadendorf, Dirk, Long, Georgina V, Nathan, Paul D, Ascierto, Paolo A
Published in Journal for immunotherapy of cancer (01.06.2022)
Published in Journal for immunotherapy of cancer (01.06.2022)
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Metastatic disease from uveal melanoma: treatment options and future prospects
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Published in British Journal of Ophthalmology (01.01.2017)
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Five-Year Outcomes with Dabrafenib plus Trametinib in Metastatic Melanoma
Robert, Caroline, Grob, Jean J, Stroyakovskiy, Daniil, Karaszewska, Boguslawa, Hauschild, Axel, Levchenko, Evgeny, Chiarion Sileni, Vanna, Schachter, Jacob, Garbe, Claus, Bondarenko, Igor, Gogas, Helen, Mandalá, Mario, Haanen, John B.A.G, Lebbé, Celeste, Mackiewicz, Andrzej, Rutkowski, Piotr, Nathan, Paul D, Ribas, Antoni, Davies, Michael A, Flaherty, Keith T, Burgess, Paul, Tan, Monique, Gasal, Eduard, Voi, Maurizio, Schadendorf, Dirk, Long, Georgina V
Published in The New England journal of medicine (15.08.2019)
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Randomized Phase III Trial Evaluating Spartalizumab Plus Dabrafenib and Trametinib for BRAF V600-Mutant Unresectable or Metastatic Melanoma
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Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma: safety run-in and biomarker cohorts of COMBI-i
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Published in Nature medicine (01.10.2020)
Published in Nature medicine (01.10.2020)
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Circulating tumour DNA in patients with advanced melanoma treated with dabrafenib or dabrafenib plus trametinib: a clinical validation study
Syeda, Mahrukh M, Wiggins, Jennifer M, Corless, Broderick C, Long, Georgina V, Flaherty, Keith T, Schadendorf, Dirk, Nathan, Paul D, Robert, Caroline, Ribas, Antoni, Davies, Michael A, Grob, Jean Jacques, Gasal, Eduard, Squires, Matthew, Marker, Mahtab, Garrett, James, Brase, Jan C, Polsky, David
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Published in The lancet oncology (01.03.2021)
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Adjuvant Nivolumab versus Ipilimumab in Resected Stage III/IV Melanoma: 5-Year Efficacy and Biomarker Results from CheckMate 238
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Published in Clinical cancer research (01.09.2023)
Published in Clinical cancer research (01.09.2023)
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Study design and rationale for a randomised, placebo-controlled, double-blind study to assess the efficacy of selumetinib (AZD6244; ARRY-142886) in combination with dacarbazine in patients with metastatic uveal melanoma (SUMIT)
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Published in BMC cancer (10.06.2015)
Published in BMC cancer (10.06.2015)
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Brase, Jan C, Walter, Robert F H, Savchenko, Alexander, Gusenleitner, Daniel, Garrett, James, Schimming, Tobias, Varaljai, Renata, Castelletti, Deborah, Kim, Ju, Dakappagari, Naveen, Schultz, Ken, Robert, Caroline, Long, Georgina V, Nathan, Paul D, Ribas, Antoni, Flaherty, Keith T, Karaszewska, Boguslawa, Schachter, Jacob, Sucker, Antje, Schmid, Kurt W, Zimmer, Lisa, Livingstone, Elisabeth, Gasal, Eduard, Schadendorf, Dirk, Roesch, Alexander
Published in Clinical cancer research (15.08.2021)
Published in Clinical cancer research (15.08.2021)
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Preclinical Evidence That Trametinib Enhances the Response to Antiangiogenic Tyrosine Kinase Inhibitors in Renal Cell Carcinoma
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Published in Molecular cancer therapeutics (01.01.2016)
Published in Molecular cancer therapeutics (01.01.2016)
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CT response assessment combining reduction in both size and arterial phase density correlates with time to progression in metastatic renal cancer patients treated with targeted therapies
Nathan, P.D., Vinayan, A., Stott, D., Juttla, J., Goh, V.
Published in Cancer biology & therapy (01.01.2010)
Published in Cancer biology & therapy (01.01.2010)
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