A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment
Guyot, Anne-Cécile, Leuxe, Charlotte, Disdier, Clémence, Oumata, Nassima, Costa, Narciso, Roux, Gwenaëlle Le, Varela, Paloma F., Duchon, Arnaud, Charbonnier, Jean Baptiste, Herault, Yann, Pavoni, Serena, Galons, Hervé, Andriambeloson, Emile, Wagner, Stéphanie, Meijer, Laurent, Lund, Amie K., Mabondzo, Aloïse
Published in Scientific reports (24.01.2020)
Published in Scientific reports (24.01.2020)
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Journal Article
TRPC6 channel translocation into phagosomal membrane augments phagosomal function
Riazanski, Vladimir, Gabdoulkhakova, Aida G., Boynton, Lin S., Eguchi, Raphael R., Deriy, Ludmila V., Hogarth, D. Kyle, Loaëc, Nadège, Oumata, Nassima, Galons, Hervé, Brown, Mary E., Shevchenko, Pavel, Gallan, Alexander J., Yoo, Sang Gune, Naren, Anjaparavanda P., Villereal, Mitchel L., Beacham, Daniel W., Bindokas, Vytautas P., Birnbaumer, Lutz, Meijer, Laurent, Nelson, Deborah J.
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (24.11.2015)
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Journal Article
Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models
Vauthier, Virginie, Ben Saad, Amel, Elie, Jonathan, Oumata, Nassima, Durand-Schneider, Anne-Marie, Bruneau, Alix, Delaunay, Jean-Louis, Housset, Chantal, Aït-Slimane, Tounsia, Meijer, Laurent, Falguières, Thomas
Published in Scientific reports (30.04.2019)
Published in Scientific reports (30.04.2019)
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Journal Article
Novel Mouse Tauopathy Model for Repetitive Mild Traumatic Brain Injury: Evaluation of Long-Term Effects on Cognition and Biomarker Levels After Therapeutic Inhibition of Tau Phosphorylation
Rubenstein, Richard, Sharma, Deep R, Chang, Binggong, Oumata, Nassima, Cam, Morgane, Vaucelle, Lise, Lindberg, Mattias F, Chiu, Allen, Wisniewski, Thomas, Wang, Kevin K W, Meijer, Laurent
Published in Frontiers in neurology (11.03.2019)
Published in Frontiers in neurology (11.03.2019)
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Journal Article
Author Correction: A Small Compound Targeting Prohibitin with Potential Interest for Cognitive Deficit Rescue in Aging mice and Tau Pathology Treatment
Guyot, Anne-Cécile, Leuxe, Charlotte, Disdier, Clémence, Oumata, Nassima, Costa, Narciso, Le Roux, Gwenaëlle, Varela, Paloma F., Duchon, Arnaud, Charbonnier, Jean Baptiste, Herault, Yann, Pavoni, Serena, Galons, Hervé, Andriambeloson, Emile, Wagner, Stéphanie, Meijer, Laurent, Lund, Amie K., Mabondzo, Aloïse
Published in Scientific reports (03.07.2020)
Published in Scientific reports (03.07.2020)
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Journal Article
CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD
Bukanov, Nikolay O., Moreno, Sarah E., Natoli, Thomas A., Rogers, Kelly A., Smith, Laurie A., Ledbetter, Steven R., Oumata, Nassima, Galons, Hervé, Meijer, Laurent, Ibraghimov-Beskrovnaya, Oxana
Published in Cell cycle (Georgetown, Tex.) (01.11.2012)
Published in Cell cycle (Georgetown, Tex.) (01.11.2012)
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Journal Article
The toll-like receptor agonist imiquimod is active against prions
Oumata, Nassima, Nguyen, Phu Hai, Beringue, Vincent, Soubigou, Flavie, Pang, Yanhong, Desban, Nathalie, Massacrier, Catherine, Morel, Yannis, Paturel, Carine, Contesse, Marie-Astrid, Bouaziz, Serge, Sanyal, Suparna, Galons, Hervé, Blondel, Marc, Voisset, Cécile
Published in PloS one (16.08.2013)
Published in PloS one (16.08.2013)
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Journal Article
Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis
Meijer, Laurent, Nelson, Deborah J., Riazanski, Vladimir, Gabdoulkhakova, Aida G., Hery-Arnaud, Geneviève, Le Berre, Rozenn, Loaëc, Nadège, Oumata, Nassima, Galons, Hervé, Nowak, Emmanuel, Gueganton, Laetitia, Dorothée, Guillaume, Prochazkova, Michaela, Hall, Bradford, Kulkarni, Ashok B., Gray, Robert D., Rossi, Adriano G., Witko-Sarsat, Véronique, Norez, Caroline, Becq, Frédéric, Ravel, Denis, Mottier, Dominique, Rault, Gilles
Published in Journal of innate immunity (01.01.2016)
Published in Journal of innate immunity (01.01.2016)
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Journal Article
Specific Triazine Herbicides Induce Amyloid-β42 Production
Portelius, Erik, Durieu, Emilie, Bodin, Marion, Cam, Morgane, Pannee, Josef, Leuxe, Charlotte, Mabondzo, Aloϊse, Oumata, Nassima, Galons, Hervé, Lee, Jung Yeol, Chang, Young-Tae, Stϋber, Kathrin, Koch, Philipp, Fontaine, Gaëlle, Potier, Marie-Claude, Manousopoulou, Antigoni, Garbis, Spiros D, Covaci, Adrian, Van Dam, Debby, De Deyn, Peter, Karg, Frank, Flajolet, Marc, Omori, Chiori, Hata, Saori, Suzuki, Toshiharu, Blennow, Kaj, Zetterberg, Henrik, Meijer, Laurent
Published in Journal of Alzheimer's disease (18.10.2016)
Published in Journal of Alzheimer's disease (18.10.2016)
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Use of ATP analogs to inhibit HIV-1 transcription
Narayanan, Aarthi, Sampey, Gavin, Van Duyne, Rachel, Guendel, Irene, Kehn-Hall, Kylene, Roman, Jessica, Currer, Robert, Galons, Hervé, Oumata, Nassima, Joseph, Benoît, Meijer, Laurent, Caputi, Massimo, Nekhai, Sergei, Kashanchi, Fatah
Published in Virology (New York, N.Y.) (10.10.2012)
Published in Virology (New York, N.Y.) (10.10.2012)
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Journal Article
A Simple Isomerization of the Purine Scaffold of a Kinase Inhibitor, Roscovitine, Affords a Four- to Seven-Fold Enhancement of Its Affinity for Four CDKs. Could This Be Traced Back to Conjugation-Induced Stiffenings/Loosenings of Rotational Barriers?
El Hage, Krystel, Piquemal, Jean-Philip, Oumata, Nassima, Meijer, Laurent, Galons, Hervé, Gresh, Nohad
Published in ACS omega (31.07.2017)
Published in ACS omega (31.07.2017)
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Journal Article
Molecular mechanisms in Alzheimer's disease and related potential treatments such as structural target convergence of antibodies and simple organic molecules
Oumata, Nassima, Lu, Kui, Teng, Yuou, Cavé, Christian, Peng, Yu, Galons, Hervé, Roques, Bernard P.
Published in European journal of medicinal chemistry (05.10.2022)
Published in European journal of medicinal chemistry (05.10.2022)
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Journal Article
Synthesis and mechanism of action of new purine derivatives against triple negative breast cancer
Zhang, Qian, Sun, Guoyang, Huang, Yuna, Cui, Shanshan, Li, Tingshen, Zhao, Lianbo, Lu, Kui, Yu, Peng, Zhang, Yongmin, Galons, Herve, Oumata, Nassima, Teng, Yuou
Published in European journal of medicinal chemistry (05.12.2023)
Published in European journal of medicinal chemistry (05.12.2023)
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Journal Article
Recent advances in the development of cyclin-dependent kinase 7 inhibitors
Teng, Yuou, Lu, Kui, Zhang, Qian, Zhao, Lianbo, Huang, Yuna, Ingarra, Angela Maria, Galons, Hervé, Li, Tingshen, Cui, Shanshan, Yu, Peng, Oumata, Nassima
Published in European journal of medicinal chemistry (01.12.2019)
Published in European journal of medicinal chemistry (01.12.2019)
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Journal Article
A β-glucuronidase-responsive albumin-binding prodrug for potential selective kinase inhibitor-based cancer chemotherapy
Compain, Guillaume, Oumata, Nassima, Clarhaut, Jonathan, Péraudeau, Elodie, Renoux, Brigitte, Galons, Hervé, Papot, Sébastien
Published in European journal of medicinal chemistry (05.10.2018)
Published in European journal of medicinal chemistry (05.10.2018)
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Journal Article
Synthesis of 6-pyridylaminopurines
Demange, Luc, Oumata, Nassima, Quinton, Julia, Bouaziz, Serge, Lozach, Olivier, Meijer, Laurent, Galons, Herve
Published in Heterocycles (01.07.2008)
Published in Heterocycles (01.07.2008)
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Journal Article
Exploration of the imidazo[1,2-b]pyridazine scaffold as a protein kinase inhibitor
Bendjeddou, Lyamin Z., Loaëc, Nadège, Villiers, Benoît, Prina, Eric, Späth, Gerald F., Galons, Hervé, Meijer, Laurent, Oumata, Nassima
Published in European journal of medicinal chemistry (05.01.2017)
Published in European journal of medicinal chemistry (05.01.2017)
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Journal Article
From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity
Durieu, Emilie, Prina, Eric, Leclercq, Olivier, Oumata, Nassima, Gaboriaud-Kolar, Nicolas, Vougogiannopoulou, Konstantina, Aulner, Nathalie, Defontaine, Audrey, No, Joo Hwan, Ruchaud, Sandrine, Skaltsounis, Alexios-Leandros, Galons, Hervé, Späth, Gerald F, Meijer, Laurent, Rachidi, Najma
Published in Antimicrobial agents and chemotherapy (01.05.2016)
Published in Antimicrobial agents and chemotherapy (01.05.2016)
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Journal Article
Cyclin-dependent kinase inhibitors closer to market launch?
Galons, Hervé, Oumata, Nassima, Gloulou, Olfa, Meijer, Laurent
Published in Expert opinion on therapeutic patents (01.08.2013)
Published in Expert opinion on therapeutic patents (01.08.2013)
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Journal Article
Cyclin-dependent kinase inhibitors: a survey of recent patent literature
Galons, Hervé, Oumata, Nassima, Meijer, Laurent
Published in Expert opinion on therapeutic patents (01.03.2010)
Published in Expert opinion on therapeutic patents (01.03.2010)
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