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A pathology foundation model for cancer diagnosis and prognosis prediction
Wang, Xiyue, Zhao, Junhan, Marostica, Eliana, Yuan, Wei, Jin, Jietian, Zhang, Jiayu, Li, Ruijiang, Tang, Hongping, Wang, Kanran, Li, Yu, Wang, Fang, Peng, Yulong, Zhu, Junyou, Zhang, Jing, Jackson, Christopher R., Zhang, Jun, Dillon, Deborah, Lin, Nancy U., Sholl, Lynette, Denize, Thomas, Meredith, David, Ligon, Keith L., Signoretti, Sabina, Ogino, Shuji, Golden, Jeffrey A., Nasrallah, MacLean P., Han, Xiao, Yang, Sen, Yu, Kun-Hsing
Published in Nature (London) (24.10.2024)
Published in Nature (London) (24.10.2024)
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A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
O'Rourke, Donald M, Nasrallah, MacLean P, Desai, Arati, Melenhorst, Jan J, Mansfield, Keith, Morrissette, Jennifer J D, Martinez-Lage, Maria, Brem, Steven, Maloney, Eileen, Shen, Angela, Isaacs, Randi, Mohan, Suyash, Plesa, Gabriela, Lacey, Simon F, Navenot, Jean-Marc, Zheng, Zhaohui, Levine, Bruce L, Okada, Hideho, June, Carl H, Brogdon, Jennifer L, Maus, Marcela V
Published in Science translational medicine (19.07.2017)
Published in Science translational medicine (19.07.2017)
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Intrathecal bivalent CAR T cells targeting EGFR and IL13Rα2 in recurrent glioblastoma: phase 1 trial interim results
Bagley, Stephen J., Logun, Meghan, Fraietta, Joseph A., Wang, Xin, Desai, Arati S., Bagley, Linda J., Nabavizadeh, Ali, Jarocha, Danuta, Martins, Rene, Maloney, Eileen, Lledo, Lester, Stein, Carly, Marshall, Amy, Leskowitz, Rachel, Jadlowsky, Julie K., Christensen, Shannon, Oner, Bike Su, Plesa, Gabriela, Brennan, Andrea, Gonzalez, Vanessa, Chen, Fang, Sun, Yusha, Gladney, Whitney, Barrett, David, Nasrallah, MacLean P., Hwang, Wei-Ting, Ming, Guo-Li, Song, Hongjun, Siegel, Donald L., June, Carl H., Hexner, Elizabeth O., Binder, Zev A., O’Rourke, Donald M.
Published in Nature medicine (01.05.2024)
Published in Nature medicine (01.05.2024)
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CDPNet: a radiomic feature learning method with epigenetic application to estimating MGMT promoter methylation status in glioblastoma
Guo, Jun, Yu, Fanyang, Nasrallah, MacLean P, Davatzikos, Christos
Published in Proceedings of SPIE, the international society for optical engineering (01.02.2024)
Published in Proceedings of SPIE, the international society for optical engineering (01.02.2024)
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Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1
Cimino, Patrick J., Ketchum, Courtney, Turakulov, Rust, Singh, Omkar, Abdullaev, Zied, Giannini, Caterina, Pytel, Peter, Lopez, Giselle Yvette, Colman, Howard, Nasrallah, MacLean P., Santi, Mariarita, Fernandes, Igor Lima, Nirschl, Jeff, Dahiya, Sonika, Neill, Stewart, Solomon, David, Perez, Eilis, Capper, David, Mani, Haresh, Caccamo, Dario, Ball, Matthew, Badruddoja, Michael, Chkheidze, Rati, Camelo-Piragua, Sandra, Fullmer, Joseph, Alexandrescu, Sanda, Yeaney, Gabrielle, Eberhart, Charles, Martinez-Lage, Maria, Chen, Jie, Zach, Leor, Kleinschmidt-DeMasters, B. K., Hefti, Marco, Lopes, Maria-Beatriz, Nuechterlein, Nicholas, Horbinski, Craig, Rodriguez, Fausto J., Quezado, Martha, Pratt, Drew, Aldape, Kenneth
Published in Acta neuropathologica (01.01.2023)
Published in Acta neuropathologica (01.01.2023)
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Clinical measures, radiomics, and genomics offer synergistic value in AI-based prediction of overall survival in patients with glioblastoma
Fathi Kazerooni, Anahita, Saxena, Sanjay, Toorens, Erik, Tu, Danni, Bashyam, Vishnu, Akbari, Hamed, Mamourian, Elizabeth, Sako, Chiharu, Koumenis, Costas, Verginadis, Ioannis, Verma, Ragini, Shinohara, Russell T., Desai, Arati S., Lustig, Robert A., Brem, Steven, Mohan, Suyash, Bagley, Stephen J., Ganguly, Tapan, O’Rourke, Donald M., Bakas, Spyridon, Nasrallah, MacLean P., Davatzikos, Christos
Published in Scientific reports (24.05.2022)
Published in Scientific reports (24.05.2022)
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Multimodal Explainable Artificial Intelligence for Prognostic Stratification of Patients With Glioblastoma
Baheti, Bhakti, Rai, Sunny, Innani, Shubham, Mehdiratta, Garv, Bell, William Robert, Guntuku, Sharath Chandra, Nasrallah, MacLean P., Bakas, Spyridon
Published in Modern pathology (01.09.2025)
Published in Modern pathology (01.09.2025)
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Radiomic MRI signature reveals three distinct subtypes of glioblastoma with different clinical and molecular characteristics, offering prognostic value beyond IDH1
Rathore, Saima, Akbari, Hamed, Rozycki, Martin, Abdullah, Kalil G., Nasrallah, MacLean P., Binder, Zev A., Davuluri, Ramana V., Lustig, Robert A., Dahmane, Nadia, Bilello, Michel, O’Rourke, Donald M., Davatzikos, Christos
Published in Scientific reports (23.03.2018)
Published in Scientific reports (23.03.2018)
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Prognostic stratification of glioblastoma patients by unsupervised clustering of morphology patterns on whole slide images furthering our disease understanding
Baheti, Bhakti, Innani, Shubham, Nasrallah, MacLean, Bakas, Spyridon
Published in Frontiers in neuroscience (20.05.2024)
Published in Frontiers in neuroscience (20.05.2024)
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Neuropathology associated with SARS-CoV-2 infection
Nasrallah, MacLean P, Mourelatos, Zissimos, Lee, Edward B
Published in The Lancet (British edition) (23.01.2021)
Published in The Lancet (British edition) (23.01.2021)
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Locally secreted BiTEs complement CAR T cells by enhancing killing of antigen heterogeneous solid tumors
Yin, Yibo, Rodriguez, Jesse L., Li, Nannan, Thokala, Radhika, Nasrallah, MacLean P., Hu, Li, Zhang, Logan, Zhang, Jiasi Vicky, Logun, Meghan T., Kainth, Devneet, Haddad, Leila, Zhao, Yang, Wu, Tong, Johns, Emily X., Long, Yu, Liang, Hongsheng, Qi, Jiping, Zhang, Xiangtong, Binder, Zev A., Lin, Zhiguo, O’Rourke, Donald M.
Published in Molecular therapy (06.07.2022)
Published in Molecular therapy (06.07.2022)
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Multiparametric magnetic resonance imaging in the assessment of anti-EGFRvIII chimeric antigen receptor T cell therapy in patients with recurrent glioblastoma
Wang, Sumei, O’Rourke, Donald M., Chawla, Sanjeev, Verma, Gaurav, Nasrallah, MacLean P., Morrissette, Jennifer J. D., Plesa, Gabriela, June, Carl H., Brem, Steven, Maloney, Eileen, Desai, Arati, Wolf, Ronald L., Poptani, Harish, Mohan, Suyash
Published in British journal of cancer (08.01.2019)
Published in British journal of cancer (08.01.2019)
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Withdrawn as duplicate: Commentary: "Zooming in" on Glioblastoma: Understanding Tumor Heterogeneity and its Clinical Implications in the Era of Single-Cell Ribonucleic Acid Sequencing
Lucas, Alfredo, Eberwine, James H, Bagley, Stephen J, Fan, Yi, Nasrallah, MacLean, Brem, Steven
Published in Neurosurgery (01.10.2021)
Published in Neurosurgery (01.10.2021)
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Applications of Radiomics and Radiogenomics in High-Grade Gliomas in the Era of Precision Medicine
Fathi Kazerooni, Anahita, Bagley, Stephen J., Akbari, Hamed, Saxena, Sanjay, Bagheri, Sina, Guo, Jun, Chawla, Sanjeev, Nabavizadeh, Ali, Mohan, Suyash, Bakas, Spyridon, Davatzikos, Christos, Nasrallah, MacLean P.
Published in Cancers (25.11.2021)
Published in Cancers (25.11.2021)
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Assessment of treatment response to dendritic cell vaccine in patients with glioblastoma using a multiparametric MRI-based prediction model
de Godoy, Laiz Laura, Chawla, Sanjeev, Brem, Steven, Wang, Sumei, O’Rourke, Donald M., Nasrallah, MacLean P., Desai, Arati, Loevner, Laurie A., Liau, Linda M., Mohan, Suyash
Published in Journal of neuro-oncology (01.05.2023)
Published in Journal of neuro-oncology (01.05.2023)
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Direct enzymatic sequencing of 5-methylcytosine at single-base resolution
Wang, Tong, Fowler, Johanna M., Liu, Laura, Loo, Christian E., Luo, Meiqi, Schutsky, Emily K., Berríos, Kiara N., DeNizio, Jamie E., Dvorak, Ashley, Downey, Nick, Montermoso, Saira, Pingul, Bianca Y., Nasrallah, MacLean, Gosal, Walraj S., Wu, Hao, Kohli, Rahul M.
Published in Nature chemical biology (01.08.2023)
Published in Nature chemical biology (01.08.2023)
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Histopathology‐validated machine learning radiographic biomarker for noninvasive discrimination between true progression and pseudo‐progression in glioblastoma
Akbari, Hamed, Rathore, Saima, Bakas, Spyridon, Nasrallah, MacLean P., Shukla, Gaurav, Mamourian, Elizabeth, Rozycki, Martin, Bagley, Stephen J., Rudie, Jeffrey D., Flanders, Adam E., Dicker, Adam P., Desai, Arati S., O’Rourke, Donald M., Brem, Steven, Lustig, Robert, Mohan, Suyash, Wolf, Ronald L., Bilello, Michel, Martinez‐Lage, Maria, Davatzikos, Christos
Published in Cancer (01.06.2020)
Published in Cancer (01.06.2020)
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Validation of multiparametric MRI based prediction model in identification of pseudoprogression in glioblastomas
de Godoy, Laiz Laura, Mohan, Suyash, Wang, Sumei, Nasrallah, MacLean P., Sakai, Yu, O’Rourke, Donald M., Bagley, Stephen, Desai, Arati, Loevner, Laurie A., Poptani, Harish, Chawla, Sanjeev
Published in Journal of translational medicine (28.04.2023)
Published in Journal of translational medicine (28.04.2023)
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Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy
Logun, Meghan, Wang, Xin, Sun, Yusha, Bagley, Stephen J., Li, Nannan, Desai, Arati, Zhang, Daniel Y., Nasrallah, MacLean P., Pai, Emily Ling-Lin, Oner, Bike Su, Plesa, Gabriela, Siegel, Donald, Binder, Zev A., Ming, Guo-li, Song, Hongjun, O’Rourke, Donald M.
Published in Cell stem cell (06.02.2025)
Published in Cell stem cell (06.02.2025)
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