Design and synthesis of aminopyridine containing biaryls reducing c-MYC protein levels in cells
Di Marco, Christina N., Terrell, Lamont, Sanchez, Robert, Rueda, Lourdes, Shuster, Leanna, Nartey, Eldridge N., McHugh, Charles, Mack, James F., Shu, Arthur, Tian, Xinrong, Medina, Jesus R., Rivero, Ralph, Manetsch, Roman, Heerding, Dirk, Mangatt, Biju
Published in Bioorganic & medicinal chemistry letters (15.08.2023)
Published in Bioorganic & medicinal chemistry letters (15.08.2023)
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Cell-Based Drug Discovery: Identification and Optimization of Small Molecules that Reduce c‑MYC Protein Levels in Cells
Medina, Jesús R, Tian, Xinrong, Li, William H, Suarez, Dominic, Mack, James F, LaFrance, Louis, Martyr, Cuthbert, Brackley, James, Di Marco, Christina, Rivero, Ralph, Heerding, Dirk A, McHugh, Charles, Minthorn, Elisabeth, Bhaskar, Aishwarya, Rubin, Jacob, Butticello, Michael, Carpenter, Christopher, Nartey, Eldridge N, Berrodin, Thomas J, Kallal, Lorena A, Mangatt, Biju
Published in Journal of medicinal chemistry (11.11.2021)
Published in Journal of medicinal chemistry (11.11.2021)
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Novel WRN Helicase Inhibitors Selectively Target Microsatellite-Unstable Cancer Cells
Picco, Gabriele, Rao, Yanhua, Al Saedi, Angham, Lee, Yang, Vieira, Sara F, Bhosle, Shriram, May, Kieron, Herranz-Ors, Carmen, Walker, Samantha J, Shenje, Raynold, Dincer, Cansu, Gibson, Freddy, Banerjee, Ruby, Hewitson, Zoe, Werner, Thilo, Cottom, Joshua E, Peng, Yang, Deng, Nanhua, Zhang, Youyou, Nartey, Eldridge N, Nickels, Leng, Landis, Philip, Conticelli, Daniela, McCarten, Katrina, Bush, Jacob, Sharma, Mamta, Lightfoot, Howard, House, David, Milford, Emma, Grant, Emma K, Glogowski, Michal P, Wagner, Craig D, Bantscheff, Marcus, Rutkowska-Klute, Anna, Zappacosta, Francesca, Pettinger, Jonathan, Barthorpe, Syd, Eberl, H Christian, Jones, Brian T, Schneck, Jessica L, Murphy, Dennis J, Voest, Emile E, Taygerly, Joshua P, DeMartino, Michael P, Coelho, Matthew A, Houseley, Jonathan, Sharma, Geeta, Schwartz, Benjamin, Garnett, Mathew J
Published in Cancer discovery (02.08.2024)
Published in Cancer discovery (02.08.2024)
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Discovery of a novel and potent series of dianilinopyrimidineurea and urea isostere inhibitors of VEGFR2 tyrosine kinase
Sammond, Douglas M., Nailor, Kristen E., Veal, James M., Nolte, Robert T., Wang, Liping, Knick, Victoria B., Rudolph, Sharon K., Truesdale, Anne T., Nartey, Eldridge N., Stafford, Jeffrey A., Kumar, Rakesh, Cheung, Mui
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
Published in Bioorganic & medicinal chemistry letters (01.08.2005)
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Design and effective synthesis of novel templates, 3,7-diphenyl-4-amino-thieno and furo-[3,2- c]pyridines as protein kinase inhibitors and in vitro evaluation targeting angiogenetic kinases
Miyazaki, Yasushi, Nakano, Masato, Sato, Hideyuki, Truesdale, Anne T., Stuart, J. Darren, Nartey, Eldridge N., Hightower, Kendra E., Kane-Carson, Laurie
Published in Bioorganic & medicinal chemistry letters (2007)
Published in Bioorganic & medicinal chemistry letters (2007)
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Orally active 4-amino-5-diarylurea-furo[2,3- d]pyrimidine derivatives as anti-angiogenic agent inhibiting VEGFR2 and Tie-2
Miyazaki, Yasushi, Tang, Jun, Maeda, Yutaka, Nakano, Masato, Wang, Liping, Nolte, Robert T., Sato, Hideyuki, Sugai, Masaki, Okamoto, Yuji, Truesdale, Anne T., Hassler, Daniel F., Nartey, Eldridge N., Patrick, Denis R., Ho, Maureen L., Ozawa, Kazunori
Published in Bioorganic & medicinal chemistry letters (15.03.2007)
Published in Bioorganic & medicinal chemistry letters (15.03.2007)
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Biochemical characterization of GSK1070916, a potent and selective inhibitor of Aurora B and Aurora C kinases with an extremely long residence time1
Anderson, Kelly, Lai, Zhihong, McDonald, Octerloney B, Stuart, J Darren, Nartey, Eldridge N, Hardwicke, Mary Ann, Newlander, Ken, Dhanak, Dashyant, Adams, Jerry, Patrick, Denis, Copeland, Robert A, Tummino, Peter J, Yang, Jingsong
Published in Biochemical journal (13.05.2009)
Published in Biochemical journal (13.05.2009)
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Design and Effective Synthesis of Novel Templates, 3,7-Diphenyl-4-amino-thieno and Furo-[3,2-c]pyridines as Protein Kinase Inhibitors and in vitro Evaluation Targeting Angiogenetic Kinases
Miyazaki, Yasushi, Nakano, Masato, Sato, Hideyuki, Truesdale, Anne T., Stuart, J. Darren, Nartey, Eldridge N., Hightower, Kendra E., Kane-Carson, Laurie
Published in ChemInform (08.05.2007)
Published in ChemInform (08.05.2007)
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