Early toll‐like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro‐inflammatory phenotype in rodent and human brain ischaemia models
Parada, Esther, Casas, Ana I., Palomino‐Antolin, Alejandra, Gómez‐Rangel, Vanessa, Rubio‐Navarro, Alfonso, Farré‐Alins, Victor, Narros‐Fernandez, Paloma, Guerrero‐Hue, Melania, Moreno, Juan Antonio, Rosa, Juliana M., Roda, José M., Hernández‐García, Borja J., Egea, Javier
Published in British journal of pharmacology (01.08.2019)
Published in British journal of pharmacology (01.08.2019)
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Journal Article
TLR4 pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury
Rosa, Juliana M., Farré‐Alins, Víctor, Ortega, María Cristina, Navarrete, Marta, Lopez‐Rodriguez, Ana Belen, Palomino‐Antolín, Alejandra, Fernández‐López, Elena, Vila‐del Sol, Virginia, Decouty, Céline, Narros‐Fernández, Paloma, Clemente, Diego, Egea, Javier
Published in British journal of pharmacology (01.09.2021)
Published in British journal of pharmacology (01.09.2021)
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Journal Article
Time‐dependent dual effect of NLRP3 inflammasome in brain ischaemia
Palomino‐Antolin, Alejandra, Narros‐Fernández, Paloma, Farré‐Alins, Víctor, Sevilla‐Montero, Javier, Decouty‐Pérez, Celine, Lopez‐Rodriguez, Ana Belen, Fernández, Nuria, Monge, Luis, Casas, Ana I., Calzada, María José, Egea, Javier
Published in British journal of pharmacology (01.04.2022)
Published in British journal of pharmacology (01.04.2022)
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Journal Article
Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation
Calzaferri, Francesco, Narros-Fernández, Paloma, de Pascual, Ricardo, de Diego, Antonio M.G, Nicke, Annette, Egea, Javier, García, Antonio G, de los Ríos, Cristóbal
Published in Journal of medicinal chemistry (25.02.2021)
Published in Journal of medicinal chemistry (25.02.2021)
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Journal Article
Activation of NLRP3 Is Required for a Functional and Beneficial Microglia Response after Brain Trauma
Lopez-Rodriguez, Ana Belen, Decouty-Perez, Céline, Farré-Alins, Victor, Palomino-Antolín, Alejandra, Narros-Fernández, Paloma, Egea, Javier
Published in Pharmaceutics (26.07.2022)
Published in Pharmaceutics (26.07.2022)
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Journal Article
Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux
Farré-Alins, Víctor, Narros-Fernández, Paloma, Palomino-Antolín, Alejandra, Decouty-Pérez, Céline, Lopez-Rodriguez, Ana Belen, Parada, Esther, Muñoz-Montero, Alicia, Gómez-Rangel, Vanessa, López-Muñoz, Francisco, Ramos, Eva, González-Rodríguez, Águeda, Gandía, Luis, Romero, Alejandro, Egea, Javier
Published in Antioxidants (18.12.2020)
Published in Antioxidants (18.12.2020)
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Redox Regulation of Microglial Inflammatory Response: Fine Control of NLRP3 Inflammasome through Nrf2 and NOX4
Palomino-Antolín, Alejandra, Decouty-Pérez, Céline, Farré-Alins, Víctor, Narros-Fernández, Paloma, Lopez-Rodriguez, Ana Belen, Álvarez-Rubal, María, Valencia, Inés, López-Muñoz, Francisco, Ramos, Eva, Cuadrado, Antonio, Casas, Ana I, Romero, Alejandro, Egea, Javier
Published in Antioxidants (01.09.2023)
Published in Antioxidants (01.09.2023)
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Journal Article
Serum IL-36β levels are associated with Insulin sensitivity in paediatric patients with obesity
Narros-Fernández, Paloma, O’Donnell, Andrew, Sheehy, Clodagh, Basavarajappa, Shrikanth Chomanahalli, Hernandez Santana, Yasmina Esther, Kinlen, David, Cody, Declan, Hogan, Andrew E., Walsh, Patrick T.
Published in International Journal of Obesity (01.07.2024)
Published in International Journal of Obesity (01.07.2024)
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Journal Article
Synthesis and Pharmacological Evaluation of New N‑Sulfonylureas as NLRP3 Inflammasome Inhibitors: Identification of a Hit Compound to Treat Gout
Narros-Fernández, Paloma, Chioua, Mourad, Petcu, Sonia A, Diez-Iriepa, Daniel, Cerrada-Gálvez, Laura, Decouty-Pérez, Céline, Palomino-Antolín, Alejandra, Ramos, Eva, Farré-Alins, Víctor, López-Rodríguez, Ana Belén, Romero, Alejandro, Marco-Contelles, José, Egea, Javier
Published in Journal of medicinal chemistry (28.04.2022)
Published in Journal of medicinal chemistry (28.04.2022)
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Journal Article
New roles of mitochondrial Na+ import by the Na+/Ca2+ exchanger NCLX: activation of the HIF pathway and of the NLRP3 inflammasome
Choya-Foces, Carmen, Narros-Fernández, Paloma, Hernansanz-Agustín, Pablo, Decouty, Céline, López-Rodríguez, Ana Belén, Egea, Javier, Martínez-Ruiz, Antonio
Published in Free radical biology & medicine (01.11.2023)
Published in Free radical biology & medicine (01.11.2023)
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Journal Article
New roles of mitochondrial Na+ import by the Na+/Ca2+ exchanger NCLX: activation of the HIF pathway and of the NLRP3 inflammasome
Choya-Foces, Carmen, Narros-Fernández, Paloma, Hernansanz-Agustín, Pablo, Decouty-Pérez, Céline, López-Rodríguez, Ana Belén, Egea, Javier, Martínez-Ruiz, Antonio
Published in Free radical biology & medicine (20.05.2023)
Published in Free radical biology & medicine (20.05.2023)
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Journal Article
N-SULFONYLUREA DERIVATIVES AND THE THERAPEUTIC USE THEREOF
NARROS FERNANDEZ, Paloma, EGEA MAIQUEZ, Francisco Javier, CERRADA GALVEZ, Laura, MARCO COSTELLES, José Luis, PALOMINO ANTOLIN, Alejandra, LOPEZ RODRIGUEZ, Ana Belen, DECOUTY PEREZ, Celine, FARRE ALINS, Victor
Year of Publication 16.03.2023
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Year of Publication 16.03.2023
Patent
Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients
Farré-Alins, Víctor, Palomino-Antolín, Alejandra, Narros-Fernández, Paloma, Lopez-Rodriguez, Ana Belen, Decouty-Perez, Céline, Muñoz-Montero, Alicia, Zamorano-Fernández, Jorge, Mansilla-Fernández, Beatriz, Giner-García, Javier, García-Feijoo, Pablo, Sáez-Alegre, Miguel, Palpán-Flores, Alexis J., Roda-Frade, José María, Carabias, Cristina S., Rosa, Juliana M., Civantos-Martín, Belén, Yus-Teruel, Santiago, Gandía, Luis, Lagares, Alfonso, Hernández-García, Borja J., Egea, Javier
Published in Biomedicines (25.05.2021)
Published in Biomedicines (25.05.2021)
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Journal Article
METHOD FOR DETERMINING THE EVOLUTION OF ACUTE BRAIN DAMAGE AND PHARMACEUTICAL COMPOSITION FOR TREATING SAME
YUS TERUEL, Santiago, HERNANDEZ GARCIA, Borja Jesús, NARROS FERNANDEZ, Paloma, MARTINS ROSA, Juliana, SANCHEZ CARABIAS, Cristina, PARADA PEREZ, Esther, GANDIA JUAN, Luis, PALOMINO ANTOLIN, Alejandra, FARRÉ ALINS, Victor, EGEA MÁIQUEZ, Francisco Javier, RODA FRADE, José María, LAGARES GOMEZ-ABASCAL, Alfonso
Year of Publication 02.06.2022
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Year of Publication 02.06.2022
Patent
TLR4-pathway impairs synaptic number and cerebrovascular functions through astrocyte activation following traumatic brain injury
Rosa, Juliana M, Farre-Alins, Víctor, Ortega, María Cristina, Navarrete, Marta, Lopez-Rodriguez, Ana Belen, Palomino-Antolin, Alejandra, Fernandez-Lopez, Elena, Vila-Del Sol, Virginia, Decouty, Celine, Narros-Fernandez, Paloma, Clemente, Diego, Egea, Javier
Published in bioRxiv (20.03.2021)
Published in bioRxiv (20.03.2021)
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Paper
N-SULFONYLUREA DERIVATIVES AND THEIR THERAPEUTIC USE (Machine-translation by Google Translate, not legally binding)
CERRADA GALVEZ, LAURA, DECOUTY PEREZ, CELINE, MARCO CONTELLES, JOSE LUIS, LOPEZ RODRIGUEZ, ANA BELEN, FARRE ALINS, VICTOR, EGEA MAIQUEZ, FRANCISCO JAVIER, NARROS FERNANDEZ, PALOMA, PALOMINO ANTOLIN, ALEJANDRA
Year of Publication 13.09.2023
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Year of Publication 13.09.2023
Patent
METODO PARA DETERMINAR LA EVOLUCION DEL DANO CEREBRAL AGUDO Y COMPOSICION FARMACEUTICA PARA SU TRATAMIENTO
Martins Rosa, Juliana, Yus Teruel, Santiago, Parada Pérez, Esther, Hernández García, Borja Jesús, Farré Alins, Víctor, Egea Máiquez, Francisco Javier, Lagares Gómez-Abascal, Alfonso, Sánchez Carabias, Cristina, Narros Fernández, Paloma, Roda Frade, José María, Gandía Juan, Luis, Palomino Antolín, Alejandra
Year of Publication 17.08.2023
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Year of Publication 17.08.2023
Patent
Time-dependent dual effect of NLRP3 inflammasome in brain ischemia
Palomino-Antolin, Alejandra, Narros-Fernández, Paloma, Farré-Alins, Víctor, Sevilla-Montero, Javier, Decouty-Pérez, Celine, Lopez-Rodriguez, Ana Belen, Fernández, Nuria, Monge, Luis, Casas, Ana I, Calzada, María José, Egea, Javier
Published in bioRxiv (09.10.2020)
Published in bioRxiv (09.10.2020)
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Paper
METHOD FOR EARLY DETECTION OF LIVER DAMAGE USING BONE MORPHOGENETIC PROTEIN 2 (BMP2) IN LIQUID BIOPSY (Machine-translation by Google Translate, not legally binding)
González Rodríguez, Agueda, Narros Fernández, Paloma, Rey Fernández, Esther, Marañón Barnusell, Patricia, García Monzón, Carmelo, Egea Máiquez, Javier
Year of Publication 10.02.2023
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Year of Publication 10.02.2023
Patent