CC-90009: A Cereblon E3 Ligase Modulating Drug That Promotes Selective Degradation of GSPT1 for the Treatment of Acute Myeloid Leukemia
Hansen, Joshua D, Correa, Matthew, Alexander, Matt, Nagy, Mark, Huang, Dehua, Sapienza, John, Lu, Gang, LeBrun, Laurie A, Cathers, Brian E, Zhang, Weihong, Tang, Yang, Ammirante, Massimo, Narla, Rama K, Piccotti, Joseph R, Pourdehnad, Michael, Lopez-Girona, Antonia
Published in Journal of medicinal chemistry (25.02.2021)
Published in Journal of medicinal chemistry (25.02.2021)
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Journal Article
Pomalidomide in combination with dexamethasone results in synergistic anti‐tumour responses in pre‐clinical models of lenalidomide‐resistant multiple myeloma
Rychak, Emily, Mendy, Derek, Shi, Tao, Ning, Yuhong, Leisten, Jim, Lu, Ling, Miller, Karen, Narla, Rama K., Orlowski, Robert Z., Raymon, Heather K., Bjorklund, Chad C., Thakurta, Anjan, Gandhi, Anita K., Cathers, Brian E., Chopra, Rajesh, Daniel, Thomas O., Lopez‐Girona, Antonia
Published in British journal of haematology (01.03.2016)
Published in British journal of haematology (01.03.2016)
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Journal Article
Differential Effects of Iberdomide Versus Revlimid on Leukocyte Trafficking, Immune Activation and DLBCL Tumor Cell Killing
Nakayama, Yumi, Chiu, Hsiling, Narla, Rama K., Shakya, Arvind, Gamez, Jim, Wall, Isobelle, Papazoglou, Despoina, Apollonio, Benedetta, Ramsay, Alan G., Hagner, Patrick, Gandhi, Anita K
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
CC-99282 is a Novel Cereblon (CRBN) E3 Ligase Modulator (CELMoD) Agent with Enhanced Tumoricidal Activity in Preclinical Models of Lymphoma
Carrancio, Soraya, Groocock, Lynda, Janardhanan, Preethi, Jankeel, Diana, Galasso, Ryan, Guarinos, Carla, Narla, Rama K., Groza, Matthew, Leisten, Jim, Pierce, Daniel W., Rolfe, Mark, Lopez-Girona, Antonia
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Abstract B177: Synthetic lethal approach identifies potent and selective TTK and CLK inhibitor with preclinical anticancer activity in triple-negative breast cancer model
Zhu, Dan, Deyanat-Yazdi, Gordafaried, Mikolon, David, Narla, Rama K., Peng, Sophie X., Ning, Yuhong, Riggs, Jennifer R., Boylan, John F.
Published in Molecular cancer therapeutics (01.01.2018)
Published in Molecular cancer therapeutics (01.01.2018)
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TREATMENT OF CANCER WITH TOR KINASE INHIBITORS
HEGE, KRISTEN MAE, NARLA, RAMA K, RAYMON, HEATHER, XU, SHUICHAN, LOPEZ-GIRONA, ANTONIA, CHOPRA, RAJESH
Year of Publication 10.10.2023
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Year of Publication 10.10.2023
Patent
1-ETHYL-7-(2-METHYL-6-(1H-1,2,4-TRIAZOL-3-YL)PYRIDIN-3-YL)-3,4-DIHYDROPYRAZINO[2,3-B]PYRAZIN-2(1H)-ONE FOR USE IN THE TREATMENT OF GLIOBLASTOMA MULTIFORME
HEGE, Kristen Mae, LOPEZ-GIRONA, Antonia, CHOPRA, Rajesh, XU, Shuichan, NARLA, Rama K, RAYMON, Heather
Year of Publication 21.12.2022
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Year of Publication 21.12.2022
Patent
TREATMENT OF CANCER WITH TOR KINASE INHIBITORS
HEGE, Kristen Mae, LOPEZ-GIRONA, Antonia, CHOPRA, Rajesh, XU, Shuichan, NARLA, Rama K, RAYMON, Heather
Year of Publication 01.09.2022
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Year of Publication 01.09.2022
Patent
4-(4-(4-(((2-(2,6-DIOXOPIPERIDIN-3-YL)-L-OXOISOINDOLIN-4-YL)OXY)METHYL)BENZYL)PIPERAZIN-L-YL)-3-FLUOROBENZONITRILE AS ANTIPROLIFERATIVE COMPOUND
TAVARES-GRECO, Paula, A, KERCHER, Timothy, S, PICCOTTI, Joseph, R, NARLA, Rama, K, WONG, Lilly, L, CORREA, Matthew, D, LOPEZ-GIRONA, Antonia, CARMICHAEL, James, PIERCE, Daniel, W, BRAY, Gordon, L, ARTMAN, Gerald, D., III, LU, Xiaoling, HANSEN, Joshua, CATHERS, Brian E, CARRANCIO, Soraya, NAGY, Mark, A, MAN, Hon-Wah, HAVENS, Courtney, G, ALEXANDER, Matthew, D, WHITEFIELD, Brandon, W, ZOU, Nanfei
Year of Publication 11.09.2024
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Year of Publication 11.09.2024
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TREATMENT OF CANCER WITH TOR KINASE INHIBITORS
MORTENSEN, DEBORAH, HEGE, KRISTEN MAE, NARLA, RAMA K, RAYMON, HEATHER, FULTZ, KIMBERLY ELIZABETH, TSUJI, TOSHIYA
Year of Publication 01.12.2020
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Year of Publication 01.12.2020
Patent
Antiproliferative compounds and methods of use thereof
Pierce, Daniel W, Hansen, Joshua, Lopez-Girona, Antonia, Piccotti, Joseph R, Zou, Nanfei, Whitefield, Brandon W, Artman, Gerald D, Carmichael, James, Lu, Xiaoling, Wong, Lilly L, Bray, Gordon L, Carrancio, Soraya, Cathers, Brian E, Kercher, Timothy S, Correa, Matthew D, Narla, Rama K, Nagy, Mark A, Havens, Courtney G, Alexander, Matthew D, Man, Hon-Wah, Tavares-Greco, Paula A
Year of Publication 09.07.2024
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Year of Publication 09.07.2024
Patent
ANTIPROLIFERATIVE COMPOUNDS AND METHODS OF USE THEREOF
Pierce, Daniel W, Hansen, Joshua, Lopez-Girona, Antonia, Piccotti, Joseph R, Zou, Nanfei, Whitefield, Brandon W, Artman, Gerald D, Carmichael, James, Lu, Xiaoling, Wong, Lilly L, Bray, Gordon L, Cathers, Brian E, Kercher, Timothy S, Correa, Matthew D, Carranico, Soraya, Narla, Rama K, Nagy, Mark A, Havens, Courtney G, Alexander, Matthew D, Man, Hon-Wah, Tavares-Greco, Paula A
Year of Publication 27.06.2024
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Year of Publication 27.06.2024
Patent
TREATMENT OF CANCER WITH TOR KINASE INHIBITORS
HEGE, Kristen Mae, LOPEZ-GIRONA, Antonia, CHOPRA, Rajesh, XU, Shuichan, NARLA, Rama K, RAYMON, Heather
Year of Publication 28.07.2021
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Year of Publication 28.07.2021
Patent
TREATMENT OF PROSTATE CANCER WITH TOR KINASE INHIBITORS
MORTENSEN, DEBORAH, FULTZ, KIMBERLY, ELIZABETH, HEGE, KRISTEN, MAE, RAYMON, HEATHER, NARLA, RAMA, K, TSUJI, TOSHIYA
Year of Publication 18.08.2020
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Year of Publication 18.08.2020
Patent