Orexigenic Action of Peripheral Ghrelin Is Mediated by Neuropeptide Y and Agouti-Related Protein
Chen, H. Y, Trumbauer, M. E, Chen, A. S, Weingarth, D. T, Adams, J. R, Frazier, E. G, Shen, Z, Marsh, D. J, Feighner, S. D, Guan, X.-M, Ye, Z, Nargund, R. P, Smith, R. G, Van der Ploeg, L. H. T, Howard, A. D, MacNeil, D. J, Qian, S
Published in Endocrinology (Philadelphia) (01.06.2004)
Published in Endocrinology (Philadelphia) (01.06.2004)
Get full text
Journal Article
Design and Biological Activities of L-163,191 (MK-0677): A Potent, Orally Active Growth Hormone Secretagogue
Patchett, A. A., Nargund, R. P., Tata, J. R., M.-H. Chen, Barakat, K. J., Johnston, D. B. R., Cheng, K., W. W.-S. CHan, Butler, B., Hickey, G., Jacks, T., Schleim, K., S.-S. Pong, L.-Y. P. Chaung, Chen, H. Y., Frazier, E., Leung, K. H., S.-H. L. Chiu, Smith, Roy G.
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.1995)
Published in Proceedings of the National Academy of Sciences - PNAS (18.07.1995)
Get full text
Journal Article
Peptidomimetic Growth Hormone Secretagogues. Design Considerations and Therapeutic Potential
Nargund, Ravi P, Patchett, Arthur A, Bach, Mark A, Murphy, M. Gail, Smith, Roy G
Published in Journal of medicinal chemistry (13.08.1998)
Published in Journal of medicinal chemistry (13.08.1998)
Get full text
Journal Article
Repeat administration of the GH secretagogue MK-0677 increases and maintains elevated IGF-I levels in beagles
HICKEY, G. J, JACKS, T. M, SCHLEIM, K.-D, FRAZIER, E, CHEN, H. Y, KRUPA, D, FEENEY, W, NARGUND, R. P, PATCHETT, A. A, SMITH, R. G
Published in Journal of endocrinology (01.02.1997)
Published in Journal of endocrinology (01.02.1997)
Get full text
Journal Article
Peptidomimetic Regulation of Growth Hormone Secretion
Smith, Roy G, Van der Ploeg, Lex H. T, Howard, Andrew D, Feighner, Scott D, Cheng, Kang, Hickey, Gerard J, Wyvratt, Matthew J, Fisher, Mike H, Nargund, Ravi P, Patchett, Arthur A
Published in Endocrine reviews (01.10.1997)
Published in Endocrine reviews (01.10.1997)
Get full text
Journal Article
Orphan G-protein-coupled receptors and natural ligand discovery
Howard, Andrew D, McAllister, George, Feighner, Scott D, Liu, Qingyun, Nargund, Ravi P, Van der Ploeg, Lex H.T, Patchett, Arthur A
Published in Trends in Pharmacological Sciences (01.03.2001)
Published in Trends in Pharmacological Sciences (01.03.2001)
Get full text
Book Review
Journal Article
Development of a High Specific Activity Sulfur-35-Labeled Sulfonamide Radioligand That Allowed the Identification of a New Growth Hormone Secretagogue Receptor
Dean, Dennis C, Nargund, Ravi P, Pong, Sheng-Shung, Chaung, Lee-Yuh P, Griffin, Patrick, Melillo, David G, Ellsworth, Robert L, Van Der Ploeg, Lex H. T, Patchett, Arthur A, Smith, Roy G
Published in Journal of medicinal chemistry (26.04.1996)
Published in Journal of medicinal chemistry (26.04.1996)
Get full text
Journal Article
Assessing and minimizing time-dependent inhibition of cytochrome P450 3A in drug discovery: A case study with melanocortin-4 receptor agonists
Tang, W., Stearns, R. A., Wang, R. W., Miller, R. R., Chen, Q., Ngui, J., Bakshi, R. K., Nargund, R. P., Dean, D. C., Baillie, T. A.
Published in Xenobiotica (01.11.2008)
Published in Xenobiotica (01.11.2008)
Get full text
Journal Article
Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues
ZHIXIONG YE, YINGDUO GAO, LOCCO, L, PARMAR, R. M, CHAN, W. W.-S, SCHAEFFER, J. M, SMITH, R. G, PATCHETT, A. A, NARGUND, R. P, BAKSHI, R. K, CHEN, M.-H, ROHRER, S. P, FEIGHNER, S. D, PONG, S.-S, HOWARD, A. D, BLAKE, A, BIRZIN, E. T
Published in Bioorganic & medicinal chemistry letters (03.01.2000)
Published in Bioorganic & medicinal chemistry letters (03.01.2000)
Get full text
Journal Article
Synthesis and biological activities of phenyl piperazine- based peptidomimetic growth hormone secretagogues
BARAKAT, K. J, KANG CHENG, NARGUND, R. P, CHAN, W. W.-S, BUTLER, B. S, JACKS, T. M, SCHLEIM, K. D, HORA, D. F, HICKEY, G. J, SMITH, R. G, PATCHETT, A. A
Published in Bioorganic & medicinal chemistry letters (02.06.1998)
Published in Bioorganic & medicinal chemistry letters (02.06.1998)
Get full text
Journal Article
Tripeptide growth hormone secretagogues
Yang, Lihu, Morriello, Greg, Pan, Yanping, Nargund, Ravi P., Barakat, Khaled, Prendergast, Kristine, Cheng, Kang, Chan, Wanda W.-S., Smith, Roy G., Patchett, Arthur A.
Published in Bioorganic & medicinal chemistry letters (07.04.1998)
Published in Bioorganic & medicinal chemistry letters (07.04.1998)
Get full text
Journal Article
Identification of a new G-protein-linked receptor for growth hormone secretagogues
Pong, S S, Chaung, L Y, Dean, D C, Nargund, R P, Patchett, A A, Smith, R G
Published in Molecular endocrinology (Baltimore, Md.) (01.01.1996)
Published in Molecular endocrinology (Baltimore, Md.) (01.01.1996)
Get full text
Journal Article
Metabolic Activation of a 1,3-Disubstituted Piperazine Derivative: Evidence for a Novel Ring Contraction to an Imidazoline
Doss, George A, Miller, Randall R, Zhang, Zhoupeng, Teffera, Yohannes, Nargund, Ravi P, Palucki, Brenda, Park, Min K, Tang, Yui S, Evans, David C, Baillie, Thomas A, Stearns, Ralph A
Published in Chemical research in toxicology (01.02.2005)
Published in Chemical research in toxicology (01.02.2005)
Get full text
Journal Article
Spiro(indoline-3,4'-piperidine) growth hormone secretagogues as ghrelin mimetics
PALUCKI, Brenda L, FEIGHNER, Scott D, PONG, Sheng-Shung, MCKEE, Karen Kulju, HRENIUK, Donna L, TAN, Carina, HOWARD, Andrew D, VAN DER PLOEG, Lex H. Y, PATCHETT, Arthur A, NARGUND, Ravi P
Published in Bioorganic & medicinal chemistry letters (23.07.2001)
Published in Bioorganic & medicinal chemistry letters (23.07.2001)
Get full text
Journal Article
Synthesis, stability, and radiolytic decomposition of carbon-14 labeled MK0677
Jones, A.N., Dean, D.C., Jenkins, H.J., Melillo, D.G., Nargund, R.P., Wallace, M.A.
Published in Journal of labelled compounds & radiopharmaceuticals (01.06.1996)
Published in Journal of labelled compounds & radiopharmaceuticals (01.06.1996)
Get full text
Journal Article
The synthesis and activity of spiroindane growth hormone secretagogues
Tata, James R., Nargund, Ravi P., Murphy, Marcia M., Johnston, David B.R., Patchett, Arthur A., Kang Cheng, Wei, Liente, Chan, Wanda W.-S., Butler, Bridget, Jacks, Thomas M., Hickey, Gerard, Smith, Roy
Published in Bioorganic & medicinal chemistry letters (18.03.1997)
Published in Bioorganic & medicinal chemistry letters (18.03.1997)
Get full text
Journal Article
Total synthesis of the highly oxygenated quassinoid (.+-.)-klaineanone
Grieco, Paul A, Nargund, Ravi P, Parker, David T
Published in Journal of the American Chemical Society (01.08.1989)
Published in Journal of the American Chemical Society (01.08.1989)
Get full text
Journal Article
Interactions of Human Melanocortin 4 Receptor with Nonpeptide and Peptide Agonists
Pogozheva, Irina D, Chai, Biao-Xin, Lomize, Andrei L, Fong, Tung M, Weinberg, David H, Nargund, Ravi P, Mulholland, Michael W, Gantz, Ira, Mosberg, Henry I
Published in Biochemistry (Easton) (30.08.2005)
Published in Biochemistry (Easton) (30.08.2005)
Get full text
Journal Article