In vitro metabolism of TAK-438, vonoprazan fumarate, a novel potassium-competitive acid blocker
Yamasaki, Hitomi, Kawaguchi, Naohiro, Nonaka, Masami, Takahashi, Junzo, Morohashi, Akio, Hirabayashi, Hideki, Moriwaki, Toshiya, Asahi, Satoru
Published in Xenobiotica (02.12.2017)
Published in Xenobiotica (02.12.2017)
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Disposition and metabolism of TAK-438 (vonoprazan fumarate), a novel potassium-competitive acid blocker, in rats and dogs
Kogame, Akifumi, Takeuchi, Toshiyuki, Nonaka, Masami, Yamasaki, Hitomi, Kawaguchi, Naohiro, Bernards, Ai, Tagawa, Yoshihiko, Morohashi, Akio, Kondo, Takahiro, Moriwaki, Toshiya, Asahi, Satoru
Published in Xenobiotica (04.03.2017)
Published in Xenobiotica (04.03.2017)
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UDP-glucuronosyltransferase 2B15 (UGT2B15) Is the Major Enzyme Responsible for Sipoglitazar Glucuronidation in Humans: Retrospective Identification of the UGT Isoform by In Vitro Analysis and the Effect of UGT2B152 Mutation
Nishihara, Mitsuhiro, Hiura, Yuto, Kawaguchi, Naohiro, Takahashi, Junzo, Asahi, Satoru
Published in DRUG METABOLISM AND PHARMACOKINETICS (2013)
Published in DRUG METABOLISM AND PHARMACOKINETICS (2013)
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An unusual metabolic pathway of sipoglitazar, a novel antidiabetic agent: cytochrome P450-catalyzed oxidation of sipoglitazar acyl glucuronide
Nishihara, Mitsuhiro, Sudo, Miyako, Kawaguchi, Naohiro, Takahashi, Junzo, Kiyota, Yutaka, Kondo, Takahiro, Asahi, Satoru
Published in Drug metabolism and disposition (01.02.2012)
Published in Drug metabolism and disposition (01.02.2012)
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Metabolic Fate of Sipoglitazar a Novel Oral PPAR Agonist with Activities for PPAR-γ, -α and -δ, in Rats and Monkeys and Comparison with Humans In Vitro
Nishihara, Mitsuhiro, Sudo, Miyako, Kamiguchi, Hidenori, Kawaguchi, Naohiro, Maeshiba, Yoshihiro, Kiyota, Yutaka, Takahashi, Junzo, Tagawa, Yoshihiko, Kondo, Takahiro, Asahi, Satoru
Published in Drug metabolism and pharmacokinetics (2012)
Published in Drug metabolism and pharmacokinetics (2012)
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Metabolic Fate of Sipoglitazar, a Novel Oral PPAR Agonist with Activities for PPAR-γ,-α and -δ, in Rats and Monkeys and Comparison with Humans In Vitro
Mitsuhiro NISHIHARA, Miyako SUDO, Hidenori KAMIGUCHI, Naohiro KAWAGUCHI, Yoshihiro MAESHIBA, Yutaka KIYOTA, Junzo TAKAHASHI, Yoshihiko TAGAWA, Takahiro KONDO, Satoru ASAHI
Published in DRUG METABOLISM AND PHARMACOKINETICS (25.04.2012)
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Published in DRUG METABOLISM AND PHARMACOKINETICS (25.04.2012)
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Antihypertensive, insulin-sensitising and renoprotective effects of a novel, potent and long-acting angiotensin II type 1 receptor blocker, azilsartan medoxomil, in rat and dog models
Kusumoto, Keiji, Igata, Hideki, Ojima, Mami, Tsuboi, Ayako, Imanishi, Mitsuaki, Yamaguchi, Fuminari, Sakamoto, Hiroki, Kuroita, Takanobu, Kawaguchi, Naohiro, Nishigaki, Nobuhiro, Nagaya, Hideaki
Published in European journal of pharmacology (01.11.2011)
Published in European journal of pharmacology (01.11.2011)
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Absorption of TAK-491, a new angiotensin II receptor antagonist, in animals
Kawaguchi, Naohiro, Ebihara, Takuya, Takeuchi, Toshiyuki, Morohashi, Akio, Yamasaki, Hitomi, Tagawa, Yoshihiko, Takahashi, Junzo, Kondo, Takahiro, Asahi, Satoru
Published in Xenobiotica (01.02.2013)
Published in Xenobiotica (01.02.2013)
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Abstract DD01-03: TAK-700, an inhibitor of 17,20-lyase
Yamaoka, Masuo, Hara, Takahito, Miki, Hiroshi, Hitaka, Takenori, Kaku, Tomohiro, Kawaguchi, Naohiro, Yamasaki, Hitomi, Takeuchi, Toshiyuki, Tasaka, Akihiro, Kusaka, Masami
Published in Cancer research (Chicago, Ill.) (15.04.2010)
Published in Cancer research (Chicago, Ill.) (15.04.2010)
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