Maximizing Diversity from a Kinase Screen: Identification of Novel and Selective pan-Trk Inhibitors for Chronic Pain
Stachel, Shawn J, Sanders, John M, Henze, Darrell A, Rudd, Mike T, Su, Hua-Poo, Li, Yiwei, Nanda, Kausik K, Egbertson, Melissa S, Manley, Peter J, Jones, Kristen L. G, Brnardic, Edward J, Green, Ahren, Grobler, Jay A, Hanney, Barbara, Leitl, Michael, Lai, Ming-Tain, Munshi, Vandna, Murphy, Dennis, Rickert, Keith, Riley, Daniel, Krasowska-Zoladek, Alicja, Daley, Christopher, Zuck, Paul, Kane, Stephanie A, Bilodeau, Mark T
Published in Journal of medicinal chemistry (10.07.2014)
Published in Journal of medicinal chemistry (10.07.2014)
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Journal Article
Imidazopyridine CB2 agonists: Optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy
Trotter, B. Wesley, Nanda, Kausik K., Burgey, Christopher S., Potteiger, Craig M., Deng, James Z., Green, Ahren I., Hartnett, John C., Kett, Nathan R., Wu, Zhicai, Henze, Darrell A., Penna, Kimberly Della, Desai, Reshma, Leitl, Michael D., Lemaire, Wei, White, Rebecca B., Yeh, Suzie, Urban, Mark O., Kane, Stefanie A., Hartman, George D., Bilodeau, Mark T.
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
Published in Bioorganic & medicinal chemistry letters (15.04.2011)
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Journal Article
Design and Synthesis of Novel Isoquinoline-3-nitriles as Orally Bioavailable Kv1.5 Antagonists for the Treatment of Atrial Fibrillation
Trotter, B. Wesley, Nanda, Kausik K, Kett, Nathan R, Regan, Christopher P, Lynch, Joseph J, Stump, Gary L, Kiss, Laszlo, Wang, Jixin, Spencer, Robert H, Kane, Stefanie A, White, Rebecca B, Zhang, Rena, Anderson, Kenneth D, Liverton, Nigel J, McIntyre, Charles J, Beshore, Douglas C, Hartman, George D, Dinsmore, Christopher J
Published in Journal of medicinal chemistry (30.11.2006)
Published in Journal of medicinal chemistry (30.11.2006)
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Journal Article
Inhibition of N-Nitrosamine Formation in Drug Products: A Model Study
Nanda, Kausik K., Tignor, Steven, Clancy, James, Marota, Melanie J., Allain, Leonardo R., D'Addio, Suzanne M.
Published in Journal of pharmaceutical sciences (01.12.2021)
Published in Journal of pharmaceutical sciences (01.12.2021)
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Journal Article
Enrichment of Relevant Oxidative Degradation Products in Pharmaceuticals With Targeted Chemoselective Oxidation
Nanda, Kausik K., Mozziconacci, Olivier, Small, James, Allain, Leonardo R., Helmy, Roy, Wuelfing, W. Peter
Published in Journal of pharmaceutical sciences (01.04.2019)
Published in Journal of pharmaceutical sciences (01.04.2019)
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Journal Article
Lead optimization of cathepsin K inhibitors for the treatment of Osteoarthritis
Ginnetti, Anthony T., Paone, Daniel V., Nanda, Kausik K., Li, Jing, Busuek, Marina, Johnson, Scott A., Lu, Jun, Soisson, Stephen M., Robinson, Ronald, Fisher, John, Webber, Andrea, Wesolowski, Gregg, Ma, Bennett, Duong, Le, Carroll, Steven, Burgey, Christopher S., Stachel, Shawn J.
Published in Bioorganic & medicinal chemistry letters (15.10.2022)
Published in Bioorganic & medicinal chemistry letters (15.10.2022)
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Journal Article
Identification and in Vivo Evaluation of Liver X Receptor β‑Selective Agonists for the Potential Treatment of Alzheimer’s Disease
Stachel, Shawn J, Zerbinatti, Celina, Rudd, Michael T, Cosden, Mali, Suon, Sokreine, Nanda, Kausik K, Wessner, Keith, DiMuzio, Jillian, Maxwell, Jill, Wu, Zhenhua, Uslaner, Jason M, Michener, Maria S, Szczerba, Peter, Brnardic, Edward, Rada, Vanessa, Kim, Yuntae, Meissner, Robert, Wuelfing, Peter, Yuan, Yang, Ballard, Jeanine, Holahan, Marie, Klein, Daniel J, Lu, Jun, Fradera, Xavier, Parthasarathy, Gopal, Uebele, Victor N, Chen, Zhongguo, Li, Yingjie, Li, Jian, Cooke, Andrew J, Bennett, D. Jonathan, Bilodeau, Mark T, Renger, John
Published in Journal of medicinal chemistry (14.04.2016)
Published in Journal of medicinal chemistry (14.04.2016)
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Journal Article
Iron(III)-Mediated Oxidative Degradation on the Benzylic Carbon of Drug Molecules in the Absence of Initiating Peroxides
Nanda, Kausik K., Blincoe, William D., Allain, Leonardo R., Wuelfing, W. Peter, Harmon, Paul A.
Published in Journal of pharmaceutical sciences (01.05.2017)
Published in Journal of pharmaceutical sciences (01.05.2017)
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Journal Article
Design, Synthesis, and Biological Evaluation of 1,2,3,7-Tetrahydro-6H-purin-6-one and 3,7-Dihydro-1H-purine-2,6-dione Derivatives as Corticotropin-Releasing Factor1 Receptor Antagonists
Hartz, Richard A, Nanda, Kausik K, Ingalls, Charles L, Ahuja, Vijay T, Molski, Thaddeus F, Zhang, Ge, Wong, Harvey, Peng, Yong, Kelley, Michelle, Lodge, Nicholas J, Zaczek, Robert, Gilligan, Paul J, Trainor, George L
Published in Journal of medicinal chemistry (09.09.2004)
Published in Journal of medicinal chemistry (09.09.2004)
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Journal Article
Discovery of MK-1832, a Kv1.5 inhibitor with improved selectivity and pharmacokinetics
Wolkenberg, Scott E., Nolt, M. Brad, Bilodeau, Mark T., Trotter, B. Wesley, Manley, Peter J., Kett, Nathan R., Nanda, Kausik K., Wu, Zhicai, Cato, Matthew J., Kane, Stefanie A., Kiss, Laszlo, Spencer, Robert H., Wang, Jixin, Lynch, Joseph J., Regan, Christopher P., Stump, Gary L., Li, Bing, White, Rebecca, Yeh, Suzie, Dinsmore, Christopher J., Lindsley, Craig W., Hartman, George D.
Published in Bioorganic & medicinal chemistry letters (15.02.2017)
Published in Bioorganic & medicinal chemistry letters (15.02.2017)
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Journal Article
Magneto-Structural Correlations in Macrocyclic Dinickel(II) Complexes: Tuning of Spin Exchange by Varying Stereochemistry and Auxiliary Ligands
Nanda, Kausik K, Das, Ramprasad, Thompson, Laurence K, Venkatsubramanian, Krishnan, Paul, Parimal, Nag, Kamalaksha
Published in Inorganic chemistry (01.03.1994)
Published in Inorganic chemistry (01.03.1994)
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Journal Article
Benzimidazole CB2 agonists: Design, synthesis and SAR
Nanda, Kausik K., Henze, Darrell A., Della Penna, Kimberly, Desai, Reshma, Leitl, Michael, Lemaire, Wei, White, Rebecca B., Yeh, Suzie, Brouillette, Janine N., Hartman, George D., Bilodeau, Mark T., Trotter, B. Wesley
Published in Bioorganic & medicinal chemistry letters (15.02.2014)
Published in Bioorganic & medicinal chemistry letters (15.02.2014)
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Journal Article
Synthesis and evaluation of imidazo[1,5- a]pyrazines as corticotropin releasing hormone receptor ligands
Hartz, Richard A., Gilligan, Paul J., Nanda, Kausik K., Tebben, Andrew J., Fitzgerald, Larry W., Miller, Keith
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
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Journal Article
Tricyclic imidazole antagonists of the Neuropeptide S Receptor
Trotter, B. Wesley, Nanda, Kausik K., Manley, Peter J., Uebele, Victor N., Condra, Cindra L., Gotter, Anthony L., Menzel, Karsten, Henault, Martin, Stocco, Rino, Renger, John J., Hartman, George D., Bilodeau, Mark T.
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
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Journal Article
Characterization of Non-Nitrocatechol Pan and Isoform Specific Catechol-O-methyltransferase Inhibitors and Substrates
Robinson, Ronald G, Smith, Sean M, Wolkenberg, Scott E, Kandebo, Monika, Yao, Lihang, Gibson, Christopher R, Harrison, Scott T, Polsky-Fisher, Stacey, Barrow, James C, Manley, Peter J, Mulhearn, James J, Nanda, Kausik K, Schubert, Jeffrey W, Trotter, B. Wesley, Zhao, Zhijian, Sanders, John M, Smith, Robert F, McLoughlin, Debra, Sharma, Sujata, Hall, Dawn L, Walker, Tiffany L, Kershner, Jennifer L, Bhandari, Neetesh, Hutson, Pete H, Sachs, Nancy A
Published in ACS chemical neuroscience (15.02.2012)
Published in ACS chemical neuroscience (15.02.2012)
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Journal Article