Genetic Correction of SOD1 Mutant iPSCs Reveals ERK and JNK Activated AP1 as a Driver of Neurodegeneration in Amyotrophic Lateral Sclerosis
Bhinge, Akshay, Namboori, Seema C., Zhang, Xiaoyu, VanDongen, Antonius M.J., Stanton, Lawrence W.
Published in Stem cell reports (11.04.2017)
Published in Stem cell reports (11.04.2017)
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Journal Article
ePRINT: exonuclease assisted mapping of protein-RNA interactions
Hawkins, Sophie, Mondaini, Alexandre, Namboori, Seema C, Nguyen, Grady G, Yeo, Gene W, Javed, Asif, Bhinge, Akshay
Published in Genome Biology (28.05.2024)
Published in Genome Biology (28.05.2024)
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Journal Article
Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons
Steg, Leonard C, Shireby, Gemma L, Imm, Jennifer, Davies, Jonathan P, Franklin, Alice, Flynn, Robert, Namboori, Seema C, Bhinge, Akshay, Jeffries, Aaron R, Burrage, Joe, Neilson, Grant W A, Walker, Emma M, Perfect, Leo W, Price, Jack, McAlonan, Grainne, Srivastava, Deepak P, Bray, Nicholas J, Cope, Emma L, Jones, Kimberley M, Allen, Nicholas D, Pishva, Ehsan, Dempster, Emma L, Lunnon, Katie, Mill, Jonathan, Hannon, Eilis
Published in Molecular brain (26.06.2021)
Published in Molecular brain (26.06.2021)
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Journal Article
MiR‐375 is Essential for Human Spinal Motor Neuron Development and May Be Involved in Motor Neuron Degeneration
Bhinge, Akshay, Namboori, Seema C., Bithell, Angela, Soldati, Chiara, Buckley, Noel J., Stanton, Lawrence W.
Published in Stem cells (Dayton, Ohio) (01.01.2016)
Published in Stem cells (Dayton, Ohio) (01.01.2016)
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Journal Article
MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-β/BMP signaling
Bhinge, Akshay, Poschmann, Jeremie, Namboori, Seema C, Tian, Xianfeng, Jia Hui Loh, Sharon, Traczyk, Anna, Prabhakar, Shyam, Stanton, Lawrence W
Published in The EMBO journal (02.06.2014)
Published in The EMBO journal (02.06.2014)
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Journal Article
Single-cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS iPSC-derived motor neurons
Namboori, Seema C., Thomas, Patricia, Ames, Ryan, Hawkins, Sophie, Garrett, Lawrence O., Willis, Craig R.G., Rosa, Alessandro, Stanton, Lawrence W., Bhinge, Akshay
Published in Stem cell reports (14.12.2021)
Published in Stem cell reports (14.12.2021)
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Journal Article
Upregulation of β-catenin due to loss of miR-139 contributes to motor neuron death in amyotrophic lateral sclerosis
Hawkins, Sophie, Namboori, Seema C, Tariq, Ammarah, Blaker, Catherine, Flaxman, Christine, Dey, Nidhi S, Henley, Peter, Randall, Andrew, Rosa, Alessandro, Stanton, Lawrence W, Bhinge, Akshay
Published in Stem cell reports (12.07.2022)
Published in Stem cell reports (12.07.2022)
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Journal Article
MiR-135b is a direct PAX6 target and specifies human neuroectoderm by inhibiting TGF-[beta]/BMP signaling
Bhinge, Akshay, Poschmann, Jeremie, Namboori, Seema C, Tian, Xianfeng, Jia Hui Loh, Sharon, Traczyk, Anna, Prabhakar, Shyam, Stanton, Lawrence W
Published in The EMBO journal (01.06.2014)
Published in The EMBO journal (01.06.2014)
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Journal Article
Mi R ‐135b is a direct PAX 6 target and specifies human neuroectoderm by inhibiting TGF ‐β/ BMP signaling
Bhinge, Akshay, Poschmann, Jeremie, Namboori, Seema C, Tian, Xianfeng, Jia Hui Loh, Sharon, Traczyk, Anna, Prabhakar, Shyam, Stanton, Lawrence W
Published in The EMBO journal (02.06.2014)
Published in The EMBO journal (02.06.2014)
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Journal Article
Single cell transcriptomics identifies master regulators of neurodegeneration in SOD1 ALS motor neurons
Namboori, Seema C, Thomas, Patricia, Ames, Ryan, Hawkins, Sophie, Garrett, Lawrence O, Willis, Craig R G, Rosa, Alessandro, Stanton, Lawrence W, Bhinge, Akshay
Published in bioRxiv (09.03.2021)
Published in bioRxiv (09.03.2021)
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Paper
Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons
Steg, Leonard C, Shireby, Gemma L, Imm, Jennifer, Davies, Jonathan P, Franklin, Alice, Flynn, Robert, Namboori, Seema C, Bhinge, Akshay, Jeffries, Aaron R, Burrage, Joe, Neilson, Grant W A, Walker, Emma M, Perfect, Leo W, Price, Jack, Mcalonan, Grainne, Srivastava, Deepak P, Bray, Nicholas J, Cope, Emma L, Jones, Kimberly M, Allen, Nicholas D, Pishva, Ehsan, Dempster, Emma L, Lunnon, Katie, Mill, Jonathan, Hannon, Eilis
Published in bioRxiv (16.05.2021)
Published in bioRxiv (16.05.2021)
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Paper