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Published in Journal of pharmacological sciences (01.01.2016)
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A Double Decarboxylation Reaction of an Oxazolidinone and Carboxylic Acid: Its Application to the Synthesis of a New Opioid Lead Compound
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Published in Journal of organic chemistry (05.02.2010)
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Effects of TRK-820, a selective kappa opioid receptor agonist, on rat schizophrenia models
Yoshikawa, Satoru, Hareyama, Nana, Ikeda, Ken, Kurokawa, Takahiro, Nakajima, Mayumi, Nakao, Kaoru, Mochizuki, Hidenori, Ichinose, Hiroshi
Published in European journal of pharmacology (15.03.2009)
Published in European journal of pharmacology (15.03.2009)
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Pharmacological and clinical profiles of nalfurafine hydrochloride (Remitch) capsules 2.5 microg) , a new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients
Nakao, Kaoru, Ando, Akihiro, Hirakata, Mikito, Ando, Naoki, Takeshita, Koichiro, Miyamoto, Yohei, Mochizuki, Hidenori
Published in Nihon yakurigaku zasshi (01.05.2010)
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Published in Nihon yakurigaku zasshi (01.05.2010)
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Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration
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Published in Bioorganic & medicinal chemistry letters (01.11.2010)
Published in Bioorganic & medicinal chemistry letters (01.11.2010)
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Pharmacological Effect of TRK-380, a Novel Selective Human β3 -Adrenoceptor Agonist, on Mammalian Detrusor Strips
Kanie, Sayoko, Otsuka, Atsushi, Yoshikawa, Satoru, Morimoto, Takashi, Hareyama, Nana, Okazaki, Seiji, Kobayashi, Ryosuke, Hasebe, Ko, Nakao, Kaoru, Hayashi, Ryoji, Mochizuki, Hidenori, Matsumoto, Rikiya, Ozono, Seiichiro
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Published in Urology (Ridgewood, N.J.) (01.03.2012)
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TRK-820, a selective kappa opioid receptor agonist, could effectively ameliorate L-DOPA-induced dyskinesia symptoms in a rat model of Parkinson's disease
Ikeda, Ken, Yoshikawa, Satoru, Kurokawa, Takahiro, Yuzawa, Natsumi, Nakao, Kaoru, Mochizuki, Hidenori
Published in European journal of pharmacology (12.10.2009)
Published in European journal of pharmacology (12.10.2009)
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In vitro and in vivo pharmacological characterization of the main metabolites of nalfurafine hydrochloride
Nakao, Kaoru, Togashi, Yuko, Honda, Toshiyuki, Momen, Shinobu, Umeuchi, Hideo, Sakakibara, Shinji, Tanaka, Toshiaki, Okano, Kiyoshi, Mochizuki, Hidenori
Published in European journal of pharmacology (15.11.2012)
Published in European journal of pharmacology (15.11.2012)
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Drug design and synthesis of a novel κ opioid receptor agonist with an oxabicyclo[2.2.2]octane skeleton and its pharmacology
Nagase, Hiroshi, Watanabe, Akio, Nemoto, Toru, Yamaotsu, Noriyuki, Hayashida, Kohei, Nakajima, Mayumi, Hasebe, Ko, Nakao, Kaoru, Mochizuki, Hidenori, Hirono, Shuichi, Fujii, Hideaki
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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Synthesis of novel triplet drugs with 1,3,5-trioxazatriquinane skeletons and their pharmacologies. Part 2: Synthesis of novel triplet drugs with the epoxymethano structure (capped homotriplet)
Nagase, Hiroshi, Koyano, Koji, Wada, Naohisa, Hirayama, Shigeto, Watanabe, Akio, Nemoto, Toru, Nakajima, Mayumi, Nakao, Kaoru, Mochizuki, Hidenori, Fujii, Hideaki
Published in Bioorganic & medicinal chemistry letters (15.10.2011)
Published in Bioorganic & medicinal chemistry letters (15.10.2011)
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Involvement of central μ-opioid system in the scratching behavior in mice, and the suppression of it by the activation of κ-opioid system
Umeuchi, Hideo, Togashi, Yuko, Honda, Toshiyuki, Nakao, Kaoru, Okano, Kiyoshi, Tanaka, Toshiaki, Nagase, Hiroshi
Published in European journal of pharmacology (05.09.2003)
Published in European journal of pharmacology (05.09.2003)
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Investigation of Beckett–Casy model 2: Synthesis of novel 15–16 nornaltrexone derivatives and their pharmacology
Nagase, Hiroshi, Imaide, Satomi, Tomatsu, Miyuki, Nemoto, Toru, Nakajima, Mayumi, Nakao, Kaoru, Mochizuki, Hidenori, Fujii, Hideaki
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
Published in Bioorganic & medicinal chemistry letters (15.06.2010)
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Investigation of Beckett–Casy model 1: Synthesis of novel 16,17- seco-naltrexone derivatives and their pharmacology
Imaide, Satomi, Fujii, Hideaki, Watanabe, Akio, Nemoto, Toru, Nakajima, Mayumi, Nakao, Kaoru, Mochizuki, Hidenori, Nagase, Hiroshi
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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