NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism
Tu, Shichun, Akhtar, Mohd Waseem, Escorihuela, Rosa Maria, Amador-Arjona, Alejandro, Swarup, Vivek, Parker, James, Zaremba, Jeffrey D., Holland, Timothy, Bansal, Neha, Holohan, Daniel R., Lopez, Kevin, Ryan, Scott D., Chan, Shing Fai, Yan, Li, Zhang, Xiaofei, Huang, Xiayu, Sultan, Abdullah, McKercher, Scott R., Ambasudhan, Rajesh, Xu, Huaxi, Wang, Yuqiang, Geschwind, Daniel H., Roberts, Amanda J., Terskikh, Alexey V., Rissman, Robert A., Masliah, Eliezer, Lipton, Stuart A., Nakanishi, Nobuki
Published in Nature communications (14.11.2017)
Published in Nature communications (14.11.2017)
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Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer’s disease models
Lipton, Stuart A, Rezaie, Tayebeh, Nutter, Anthony, Lopez, Kevin M, Parker, James, Kosaka, Kunio, Satoh, Takumi, McKercher, Scott R, Masliah, Eliezer, Nakanishi, Nobuki
Published in Cell death & disease (01.12.2016)
Published in Cell death & disease (01.12.2016)
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NR3A-containing NMDARs promote neurotransmitter release and spike timing-dependent plasticity
Philpot, Benjamin D, Larsen, Rylan S, Corlew, Rebekah J, Henson, Maile A, Roberts, Adam C, Mishina, Masayoshi, Watanabe, Masahiko, Lipton, Stuart A, Nakanishi, Nobuki, Pérez-Otaño, Isabel, Weinberg, Richard J
Published in Nature neuroscience (01.03.2011)
Published in Nature neuroscience (01.03.2011)
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Transcription factor MEF2C influences neural stem/progenitor cell differentiation and maturation in vivo
Li, Hao, Radford, Jonathan C, Ragusa, Michael J, Shea, Katherine L, McKercher, Scott R, Zaremba, Jeffrey D, Soussou, Walid, Nie, Zhiguo, Kang, Yeon-Joo, Nakanishi, Nobuki, Okamoto, Shu-ichi, Roberts, Amanda J, Schwarz, John J, Lipton, Stuart A
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (08.07.2008)
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Journal Article
MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress
Nagar, Saumya, Noveral, Sarah M., Trudler, Dorit, Lopez, Kevin M., McKercher, Scott R., Han, Xuemei, Yates, John R., Piña-Crespo, Juan C., Nakanishi, Nobuki, Satoh, Takumi, Okamoto, Shu-ichi, Lipton, Stuart A.
Published in Proceedings of the National Academy of Sciences - PNAS (16.05.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (16.05.2017)
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NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model
Okamoto, Shu-ichi, Prikhodko, Olga, Pina-Crespo, Juan, Adame, Anthony, McKercher, Scott R., Brill, Laurence M., Nakanishi, Nobuki, Oh, Chang-ki, Nakamura, Tomohiro, Masliah, Eliezer, Lipton, Stuart A.
Published in Neurobiology of disease (01.07.2019)
Published in Neurobiology of disease (01.07.2019)
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Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease
Takahashi, Hiroto, Xia, Peng, Cui, Jiankun, Talantova, Maria, Bodhinathan, Karthik, Li, Wenjun, Saleem, Sofiyan, Holland, Emily A., Tong, Gary, Piña-Crespo, Juan, Zhang, Dongxian, Nakanishi, Nobuki, Larrick, James W., McKercher, Scott R., Nakamura, Tomohiro, Wang, Yuqiang, Lipton, Stuart A.
Published in Scientific reports (19.10.2015)
Published in Scientific reports (19.10.2015)
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Neuroprotection by the NR3A Subunit of the NMDA Receptor
Nakanishi, Nobuki, Tu, Shichun, Shin, Yeonsook, Cui, Jiankun, Kurokawa, Toru, Zhang, Dongxian, Chen, H.-S. Vincent, Tong, Gary, Lipton, Stuart A
Published in The Journal of neuroscience (22.04.2009)
Published in The Journal of neuroscience (22.04.2009)
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Excitatory glycine responses of CNS myelin mediated by NR1/NR3 "NMDA" receptor subunits
Piña-Crespo, Juan C, Talantova, Maria, Micu, Ileana, States, Bradley, Chen, H-S Vincent, Tu, Shichun, Nakanishi, Nobuki, Tong, Gary, Zhang, Dongxian, Heinemann, Stephen F, Zamponi, Gerald W, Stys, Peter K, Lipton, Stuart A
Published in The Journal of neuroscience (25.08.2010)
Published in The Journal of neuroscience (25.08.2010)
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Journal Article
Genetic deletion of NR3A accelerates glutamatergic synapse maturation
Henson, Maile A, Larsen, Rylan S, Lawson, Shelikha N, Pérez-Otaño, Isabel, Nakanishi, Nobuki, Lipton, Stuart A, Philpot, Benjamin D
Published in PloS one (01.08.2012)
Published in PloS one (01.08.2012)
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Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits
Lipton, Stuart A, Zhang, Dongxian, Chatterton, Jon E, Awobuluyi, Marc, Premkumar, Louis S, Takahashi, Hiroto, Talantova, Maria, Shin, Yeonsook, Cui, Jiankun, Tu, Shichun, Sevarino, Kevin A, Nakanishi, Nobuki, Tong, Gang
Published in Nature (London) (14.02.2002)
Published in Nature (London) (14.02.2002)
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The critical role of membralin in postnatal motor neuron survival and disease
Yang, Bo, Qu, Mingliang, Wang, Rengang, Chatterton, Jon E, Liu, Xiao-Bo, Zhu, Bing, Narisawa, Sonoko, Millan, Jose Luis, Nakanishi, Nobuki, Swoboda, Kathryn, Lipton, Stuart A, Zhang, Dongxian
Published in eLife (15.05.2015)
Published in eLife (15.05.2015)
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Journal Article
MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian rat model
Cho, Eun-Gyung, Zaremba, Jeffrey D, McKercher, Scott R, Talantova, Maria, Tu, Shichun, Masliah, Eliezer, Chan, Shing Fai, Nakanishi, Nobuki, Terskikh, Alexey, Lipton, Stuart A
Published in PloS one (25.08.2011)
Published in PloS one (25.08.2011)
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Modulation of NMDA Receptor Properties and Synaptic Transmission by the NR3A Subunit in Mouse Hippocampal and Cerebrocortical Neurons
Tong, Gary, Takahashi, Hiroto, Tu, Shichun, Shin, Yeonsook, Talantova, Maria, Zago, Wagner, Xia, Peng, Nie, Zhiguo, Goetz, Thomas, Zhang, Dongxian, Lipton, Stuart A, Nakanishi, Nobuki
Published in Journal of neurophysiology (01.01.2008)
Published in Journal of neurophysiology (01.01.2008)
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Journal Article
Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A
Lipton, Stuart A, Nakanishi, Nobuki, Das, Saumya, Sasaki, Yasnory F, Rothe, Thomas, Premkumar, Louis S, Takasu, Mari, Crandall, James E, Dikkes, Pieter, Conner, David A, Rayudu, Posina V, Cheung, Wing, Chen, H.-S. Vincent
Published in Nature (London) (28.05.1998)
Published in Nature (London) (28.05.1998)
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Journal Article
Temporal and regional expression of NMDA receptor subunit NR3A in the mammalian brain
Wong, Hon-Kit, Liu, Xiao-Bo, Matos, Maria F., Chan, Shing Fai, Pérez-Otaño, Isabel, Boysen, Megan, Cui, Jiankun, Nakanishi, Nobuki, Trimmer, James S., Jones, Edward G., Lipton, Stuart A., Sucher, Nikolaus J.
Published in Journal of comparative neurology (1911) (02.09.2002)
Published in Journal of comparative neurology (1911) (02.09.2002)
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Transcriptional profiling of MEF2-regulated genes in human neural progenitor cells derived from embryonic stem cells
Chan, Shing Fai, Huang, Xiayu, McKercher, Scott R., Zaidi, Rameez, Okamoto, Shu-ichi, Nakanishi, Nobuki, Lipton, Stuart A.
Published in Genomics data (01.03.2015)
Published in Genomics data (01.03.2015)
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N-Methyl-D-Aspartate Receptor Subunit NR3A in the Retina: Developmental Expression, Cellular Localization, and Functional Aspects
Sucher, Nikolaus J, Kohler, Konrad, Tenneti, Lalitha, Wong, Hon-kit, Grunder, Tatiana, Fauser, Sascha, Wheeler-Schilling, Thomas, Nakanishi, Nobuki, Lipton, Stuart A, Guenther, Elke
Published in Investigative ophthalmology & visual science (01.10.2003)
Published in Investigative ophthalmology & visual science (01.10.2003)
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Journal Article
Isogenic Human iPSC Parkinson’s Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription
Ryan, Scott D., Dolatabadi, Nima, Chan, Shing Fai, Zhang, Xiaofei, Akhtar, Mohd Waseem, Parker, James, Soldner, Frank, Sunico, Carmen R., Nagar, Saumya, Talantova, Maria, Lee, Brian, Lopez, Kevin, Nutter, Anthony, Shan, Bing, Molokanova, Elena, Zhang, Yaoyang, Han, Xuemei, Nakamura, Tomohiro, Masliah, Eliezer, Yates, John R., Nakanishi, Nobuki, Andreyev, Aleksander Y., Okamoto, Shu-ichi, Jaenisch, Rudolf, Ambasudhan, Rajesh, Lipton, Stuart A.
Published in Cell (05.12.2013)
Published in Cell (05.12.2013)
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