Clinical study and stability assessment of a novel transcutaneous influenza vaccination using a dissolving microneedle patch
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Published in Biomaterials (01.07.2015)
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Suppressive effect of black tea polyphenol theaflavins in a mouse model of ovalbumin-induced food allergy
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Published in Journal of natural medicines (01.06.2023)
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Intravenous Administration of Polyethylene Glycol-Coated (PEGylated) Proteins and PEGylated Adenovirus Elicits an Anti-PEG Immunoglobulin M Response
Shimizu, Taro, Ichihara, Masako, Yoshioka, Yasuo, Ishida, Tatsuhiro, Nakagawa, Shinsaku, Kiwada, Hiroshi
Published in Biological & pharmaceutical bulletin (01.08.2012)
Published in Biological & pharmaceutical bulletin (01.08.2012)
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(R)-Ketamine Induces a Greater Increase in Prefrontal 5-HT Release Than (S)-Ketamine and Ketamine Metabolites via an AMPA Receptor-Independent Mechanism
Ago, Yukio, Tanabe, Wataru, Higuchi, Momoko, Tsukada, Shinji, Tanaka, Tatsunori, Yamaguchi, Takumi, Igarashi, Hisato, Yokoyama, Rei, Seiriki, Kaoru, Kasai, Atsushi, Nakazawa, Takanobu, Nakagawa, Shinsaku, Hashimoto, Kenji, Hashimoto, Hitoshi
Published in The international journal of neuropsychopharmacology (01.10.2019)
Published in The international journal of neuropsychopharmacology (01.10.2019)
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The VIPR2-selective antagonist KS-133 changes macrophage polarization and exerts potent anti-tumor effects as a single agent and in combination with an anti-PD-1 antibody
Sakamoto, Kotaro, Kittikulsuth, Wararat, Miyako, Eijiro, Steeve, Akumwami, Ishimura, Rika, Nakagawa, Shinsaku, Ago, Yukio, Nishiyama, Akira
Published in PloS one (05.07.2023)
Published in PloS one (05.07.2023)
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Solution of the structure of the TNF-TNFR2 complex
Mukai, Yohei, Nakamura, Teruya, Yoshikawa, Mai, Yoshioka, Yasuo, Tsunoda, Shin-ichi, Nakagawa, Shinsaku, Yamagata, Yuriko, Tsutsumi, Yasuo
Published in Science signaling (16.11.2010)
Published in Science signaling (16.11.2010)
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A low-invasive and effective transcutaneous immunization system using a novel dissolving microneedle array for soluble and particulate antigens
Matsuo, Kazuhiko, Yokota, Yayoi, Zhai, You, Quan, Ying-Shu, Kamiyama, Fumio, Mukai, Yohei, Okada, Naoki, Nakagawa, Shinsaku
Published in Journal of controlled release (10.07.2012)
Published in Journal of controlled release (10.07.2012)
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Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza
Matsuo, Kazuhiko, Hirobe, Sachiko, Yokota, Yayoi, Ayabe, Yurika, Seto, Masashi, Quan, Ying-Shu, Kamiyama, Fumio, Tougan, Takahiro, Horii, Toshihiro, Mukai, Yohei, Okada, Naoki, Nakagawa, Shinsaku
Published in Journal of controlled release (28.06.2012)
Published in Journal of controlled release (28.06.2012)
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A novel RyR1-selective inhibitor prevents and rescues sudden death in mouse models of malignant hyperthermia and heat stroke
Yamazawa, Toshiko, Kobayashi, Takuya, Kurebayashi, Nagomi, Konishi, Masato, Noguchi, Satoru, Inoue, Takayoshi, Inoue, Yukiko U., Nishino, Ichizo, Mori, Shuichi, Iinuma, Hiroto, Manaka, Noriaki, Kagechika, Hiroyuki, Uryash, Arkady, Adams, Jose, Lopez, Jose R., Liu, Xiaochen, Diggle, Christine, Allen, Paul D., Kakizawa, Sho, Ikeda, Keigo, Lin, Bangzhong, Ikemi, Yui, Nunomura, Kazuto, Nakagawa, Shinsaku, Sakurai, Takashi, Murayama, Takashi
Published in Nature communications (13.07.2021)
Published in Nature communications (13.07.2021)
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Performance and characteristics evaluation of a sodium hyaluronate-based microneedle patch for a transcutaneous drug delivery system
Hiraishi, Yasuhiro, Nakagawa, Takeshi, Quan, Ying-Shu, Kamiyama, Fumio, Hirobe, Sachiko, Okada, Naoki, Nakagawa, Shinsaku
Published in International journal of pharmaceutics (30.01.2013)
Published in International journal of pharmaceutics (30.01.2013)
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Development and Clinical Study of a Self-Dissolving Microneedle Patch for Transcutaneous Immunization Device
Hirobe, Sachiko, Azukizawa, Hiroaki, Matsuo, Kazuhiko, Zhai, You, Quan, Ying-Shu, Kamiyama, Fumio, Suzuki, Hiroshi, Katayama, Ichiro, Okada, Naoki, Nakagawa, Shinsaku
Published in Pharmaceutical research (01.10.2013)
Published in Pharmaceutical research (01.10.2013)
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Clinical study of a retinoic acid-loaded microneedle patch for seborrheic keratosis or senile lentigo
Hirobe, Sachiko, Otsuka, Risa, Iioka, Hiroshi, Quan, Ying-Shu, Kamiyama, Fumio, Asada, Hideo, Okada, Naoki, Nakagawa, Shinsaku
Published in Life sciences (1973) (01.01.2017)
Published in Life sciences (1973) (01.01.2017)
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Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application
Nabeshi, Hiromi, Yoshikawa, Tomoaki, Matsuyama, Keigo, Nakazato, Yasutaro, Matsuo, Kazuhiko, Arimori, Akihiro, Isobe, Masaaki, Tochigi, Saeko, Kondoh, Sayuri, Hirai, Toshiro, Akase, Takanori, Yamashita, Takuya, Yamashita, Kohei, Yoshida, Tokuyuki, Nagano, Kazuya, Abe, Yasuhiro, Yoshioka, Yasuo, Kamada, Haruhiko, Imazawa, Takayoshi, Itoh, Norio, Nakagawa, Shinsaku, Mayumi, Tadanori, Tsunoda, Shin-ichi, Tsutsumi, Yasuo
Published in Biomaterials (01.04.2011)
Published in Biomaterials (01.04.2011)
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Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis
Kitakami, Ryota, Inui, Kishin, Nakagawa, Yusuke, Sawai, Yurika, Katayama, Wakana, Yokoyama, Takeshi, Okada, Takuya, Kanamitsu, Kayoko, Nakagawa, Shinsaku, Toyooka, Naoki, Mizuguchi, Mineyuki
Published in Bioorganic & medicinal chemistry (15.08.2021)
Published in Bioorganic & medicinal chemistry (15.08.2021)
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Generation of KS-133 as a Novel Bicyclic Peptide with a Potent and Selective VIPR2 Antagonist Activity that Counteracts Cognitive Decline in a Mouse Model of Psychiatric Disorders
Sakamoto, Kotaro, Chen, Lu, Miyaoka, Tatsunori, Yamada, Mei, Masutani, Teruaki, Ishimoto, Kenji, Hino, Nobumasa, Nakagawa, Shinsaku, Asano, Satoshi, Ago, Yukio
Published in Frontiers in pharmacology (04.11.2021)
Published in Frontiers in pharmacology (04.11.2021)
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Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors
NAGANO, KAZUYA, IMAI, SUNAO, ZHAO, XILULI, YAMASHITA, TAKUYA, YOSHIOKA, YASUO, ABE, YASUHIRO, MUKAI, YOHEI, KAMADA, HARUHIKO, NAKAGAWA, SHINSAKU, TSUTSUMI, YASUO, TSUNODA, SHIN-ICHI
Published in International journal of oncology (01.07.2015)
Published in International journal of oncology (01.07.2015)
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Development of a novel therapeutic approach using a retinoic acid-loaded microneedle patch for seborrheic keratosis treatment and safety study in humans
Hiraishi, Yasuhiro, Hirobe, Sachiko, Iioka, Hiroshi, Quan, Ying-Shu, Kamiyama, Fumio, Asada, Hideo, Okada, Naoki, Nakagawa, Shinsaku
Published in Journal of controlled release (28.10.2013)
Published in Journal of controlled release (28.10.2013)
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