Diabetes-Associated Mutations in Insulin Identify Invariant Receptor Contacts
Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Wang, Shuhua, Wang, Run-Ying, Nakagawa, Satoe H, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Diabetes (New York, N.Y.) (01.06.2004)
Published in Diabetes (New York, N.Y.) (01.06.2004)
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Design of an Active Ultrastable Single-chain Insulin Analog: SYNTHESIS, STRUCTURE, AND THERAPEUTIC IMPLICATIONS
Hua, Qing-xin, Nakagawa, Satoe H, Jia, Wenhua, Huang, Kun, Phillips, Nelson B, Hu, Shi-quan, Weiss, Michael A
Published in The Journal of biological chemistry (23.05.2008)
Published in The Journal of biological chemistry (23.05.2008)
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A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor: PHOTO-CROSS-LINKING AND MUTAGENESIS OF A DIABETES-RELATED CREVICE
Huang, Kun, Chan, Shu Jin, Hua, Qing-xin, Chu, Ying-Chi, Wang, Run-ying, Klaproth, Birgit, Jia, Wenhua, Whittaker, Jonathan, De Meyts, Pierre, Nakagawa, Satoe H, Steiner, Donald F, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (30.11.2007)
Published in The Journal of biological chemistry (30.11.2007)
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Chiral Mutagenesis of Insulin: CONTRIBUTION OF THE B20-B23 β-TURN TO ACTIVITY AND STABILITY
Nakagawa, Satoe H, Hua, Qing-xin, Hu, Shi-Quan, Jia, Wenhua, Wang, Shuhua, Katsoyannis, Panayotis G, Weiss, Michael A
Published in The Journal of biological chemistry (04.08.2006)
Published in The Journal of biological chemistry (04.08.2006)
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Journal Article
Diabetes-Associated Mutations in a β -Cell Transcription Factor Destabilize an Antiparallel "Mini-Zipper" in a Dimerization Interface
Hua, Qing-Xin, Zhao, Ming, Narayana, Narendra, Nakagawa, Satoe H., Jia, Wenhua, Weiss, Michael A.
Published in Proceedings of the National Academy of Sciences - PNAS (29.02.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (29.02.2000)
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Chiral Mutagenesis of Insulin. Foldability and Function Are Inversely Regulated by a Stereospecific Switch in the B Chain
Nakagawa, Satoe H, Zhao, Ming, Hua, Qing-xin, Hu, Shi-Quan, Wan, Zhu-li, Jia, Wenhua, Weiss, Michael A
Published in Biochemistry (Easton) (05.04.2005)
Published in Biochemistry (Easton) (05.04.2005)
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How insulin binds: the B-chain alpha-helix contacts the L1 beta-helix of the insulin receptor
Huang, Kun, Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Hua, Qing-Xin, Qu, Yan, Li, Biaoru, Wang, Shuhua, Wang, Run-Ying, Nakagawa, Satoe H, Theede, Anne Mette, Whittaker, Jonathan, De Meyts, Pierre, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Journal of molecular biology (06.08.2004)
Published in Journal of molecular biology (06.08.2004)
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Journal Article
Diabetes-Associated Mutations in Insulin: Consecutive Residues in the B Chain Contact Distinct Domains of the Insulin Receptor
Xu, Bin, Hu, Shi-Quan, Chu, Ying-Chi, Huang, Kun, Nakagawa, Satoe H, Whittaker, Jonathan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (06.07.2004)
Published in Biochemistry (Easton) (06.07.2004)
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Journal Article
A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor
Hua, Qing-Xin, Nakagawa, Satoe H, Wilken, Jill, Ramos, Rowena R, Jia, Wenhua, Bass, Joseph, Weiss, Michael A
Published in Genes & development (01.04.2003)
Published in Genes & development (01.04.2003)
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Journal Article
Enhancing the Activity of Insulin at the Receptor Interface: Crystal Structure and Photo-Cross-Linking of A8 Analogues
Wan, Zhuli, Xu, Bin, Huang, Kun, Chu, Ying-Chi, Li, Biaoru, Nakagawa, Satoe H, Qu, Yan, Hu, Shi-Quan, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (28.12.2004)
Published in Biochemistry (Easton) (28.12.2004)
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Journal Article
Design of an Active Ultrastable Single-chain Insulin Analog
Hua, Qing-xin, Nakagawa, Satoe H., Jia, Wenhua, Huang, Kun, Phillips, Nelson B., Hu, Shi-quan, Weiss, Michael A.
Published in The Journal of biological chemistry (23.05.2008)
Published in The Journal of biological chemistry (23.05.2008)
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Journal Article
Hierarchical Protein Folding: Asymmetric Unfolding of an Insulin Analogue Lacking the A7−B7 Interchain Disulfide Bridge
Hua, Qing-Xin, Nakagawa, Satoe H, Jia, Wenhua, Hu, Shi-Quan, Chu, Ying-Chi, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Biochemistry (Easton) (16.10.2001)
Published in Biochemistry (Easton) (16.10.2001)
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Journal Article
Chiral mutagenesis of insulin's hidden receptor-binding surface: structure of an allo-isoleucine(A2) analogue
Xu, Bin, Hua, Qing-xin, Nakagawa, Satoe H, Jia, Wenhua, Chu, Ying-Chi, Katsoyannis, Panayotis G, Weiss, Michael A
Published in Journal of molecular biology (22.02.2002)
Published in Journal of molecular biology (22.02.2002)
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Journal Article
Chiral Mutagenesis of Insulin
Nakagawa, Satoe H., Hua, Qing-xin, Hu, Shi-Quan, Jia, Wenhua, Wang, Shuhua, Katsoyannis, Panayotis G., Weiss, Michael A.
Published in The Journal of biological chemistry (04.08.2006)
Published in The Journal of biological chemistry (04.08.2006)
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Journal Article
The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor
Huang, Kun, Chan, Shu Jin, Hua, Qing-xin, Chu, Ying-Chi, Wang, Run-ying, Klaproth, Birgit, Jia, Wenhua, Whittaker, Jonathan, De Meyts, Pierre, Nakagawa, Satoe H., Steiner, Donald F., Katsoyannis, Panayotis G., Weiss, Michael A.
Published in The Journal of biological chemistry (30.11.2007)
Published in The Journal of biological chemistry (30.11.2007)
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Journal Article
Mutational Analysis of Invariant Valine B12 in Insulin: Implications for Receptor Binding
Nakagawa, Satoe H, Tager, Howard S, Steiner, Donald F
Published in Biochemistry (Easton) (26.12.2000)
Published in Biochemistry (Easton) (26.12.2000)
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Journal Article
Protein Structure and the Spandrels of San Marco: Insulin's Receptor-Binding Surface Is Buttressed by an Invariant Leucine Essential for Its Stability
Weiss, Michael A, Nakagawa, Satoe H, Jia, Wenhua, Xu, Bin, Hua, Qing-xin, Chu, Ying-Chi, Wang, Run-ying, Katsoyannis, Panayotis G
Published in Biochemistry (Easton) (22.01.2002)
Published in Biochemistry (Easton) (22.01.2002)
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Journal Article
The use of polymer-bound oximes for the synthesis of large peptides usable in segment condensation: synthesis of a 44 amino acid amphiphilic peptide model of apolipoprotein A-1
Nakagawa, Satoe H, Lau, Herman S. H, Kezdy, F. J, Kaiser, E. T
Published in Journal of the American Chemical Society (01.11.1985)
Published in Journal of the American Chemical Society (01.11.1985)
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Journal Article
Activities of Monomeric Insulin Analogs at Position A8 Are Uncorrelated with Their Thermodynamic Stabilities
Weiss, Michael A., Hua, Qing-Xin, Jia, Wenhua, Nakagawa, Satoe H., Chu, Ying-Chi, Hu, Shi-Quan, Katsoyannis, Panayotis G.
Published in The Journal of biological chemistry (26.10.2001)
Published in The Journal of biological chemistry (26.10.2001)
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Journal Article
Non-standard insulin design: structure-activity relationships at the periphery of the insulin receptor
Weiss, Michael A, Wan, Zhuli, Zhao, Ming, Chu, Ying-Chi, Nakagawa, Satoe H, Burke, G Thomson, Jia, Wenhua, Hellmich, Rosanna, Katsoyannis, Panayotis G
Published in Journal of molecular biology (11.01.2002)
Published in Journal of molecular biology (11.01.2002)
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