Selective Peroxisome Proliferator-Activated Receptor Alpha Modulators (SPPARMα) in the Metabolic Syndrome: Is Pemafibrate Light at the End of the Tunnel?
Fruchart, Jean-Charles, Hermans, Michel P., Fruchart-Najib, Jamila, Kodama, Tatsuhiko
Published in Current atherosclerosis reports (01.01.2021)
Published in Current atherosclerosis reports (01.01.2021)
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Journal Article
Selective Peroxisome Proliferator–Activated Receptor Alpha Modulators (SPPARMα): New Opportunities to Reduce Residual Cardiovascular Risk in Chronic Kidney Disease?
Fruchart, Jean-Charles, Hermans, Michel P., Fruchart-Najib, Jamila
Published in Current atherosclerosis reports (15.07.2020)
Published in Current atherosclerosis reports (15.07.2020)
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Journal Article
Lessons from PROMINENT and prospects for pemafibrate
Fruchart, Jean-Charles, Fruchart-Najib, Jamila, Yamashita, Shizuya, Libby, Peter, Yokote, Koutaro, Kodama, Tatsuhiko, Tomita, Yohei, Ridker, Paul M., Hermans, Michel P., Zambon, Alberto
Published in Cardiovascular diabetology (29.07.2024)
Published in Cardiovascular diabetology (29.07.2024)
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Journal Article
Selective PPARα Modulator Pemafibrate and Sodium-Glucose Cotransporter 2 Inhibitor Tofogliflozin Combination Treatment Improved Histopathology in Experimental Mice Model of Non-Alcoholic Steatohepatitis
Murakami, Kentaro, Sasaki, Yusuke, Asahiyama, Masato, Yano, Wataru, Takizawa, Toshiaki, Kamiya, Wakana, Matsumura, Yoshihiro, Anai, Motonobu, Osawa, Tsuyoshi, Fruchart, Jean-Charles, Fruchart-Najib, Jamila, Aburatani, Hiroyuki, Sakai, Juro, Kodama, Tatsuhiko, Tanaka, Toshiya
Published in Cells (Basel, Switzerland) (18.02.2022)
Published in Cells (Basel, Switzerland) (18.02.2022)
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Journal Article
Mechanism of triglyceride lowering in mice expressing human apolipoprotein A5
Fruchart-Najib, Jamila, Baugé, Eric, Niculescu, Loredan-Stefan, Pham, Tatiana, Thomas, Benoit, Rommens, Corinne, Majd, Zouher, Brewer, Bryan, Pennacchio, Len A, Fruchart, Jean-Charles
Published in Biochemical and biophysical research communications (25.06.2004)
Published in Biochemical and biophysical research communications (25.06.2004)
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Journal Article
CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors
Chinetti, G, Gbaguidi, F G, Griglio, S, Mallat, Z, Antonucci, M, Poulain, P, Chapman, J, Fruchart, J C, Tedgui, A, Najib-Fruchart, J, Staels, B
Published in Circulation (New York, N.Y.) (23.05.2000)
Published in Circulation (New York, N.Y.) (23.05.2000)
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Journal Article
The orphan nuclear receptor RORα is a negative regulator of the inflammatory response
Delerive, Philippe, Monté, Didier, Dubois, Guillaume, Trottein, François, Fruchart-Najib, Jamila, Mariani, Jean, Fruchart, Jean-Charles, Staels, Bart
Published in EMBO reports (01.01.2001)
Published in EMBO reports (01.01.2001)
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Journal Article
Role of the hepatic ABCA1 transporter in modulating intrahepatic cholesterol and plasma HDL cholesterol concentrations
Basso, Federica, Freeman, Lita, Knapper, Catherine L, Remaley, Alan, Stonik, John, Neufeld, Edward B, Tansey, Terese, Amar, Marcelo J A, Fruchart-Najib, Jamila, Duverger, Nicholas, Santamarina-Fojo, Silvia, Brewer, Jr, H Bryan
Published in Journal of lipid research (01.02.2003)
Published in Journal of lipid research (01.02.2003)
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Journal Article
The ATP Binding Cassette Transporter A1 (ABCA1) Modulates the Development of Aortic Atherosclerosis in C57BL/6 and apoE-Knockout Mice
Joyce, Charles W., Marcelo J. A. Amar, Lambert, Gilles, Vaisman, Boris L., Paigen, Beverly, Najib-Fruchart, Jamila, Hoyt, Robert F., Neufeld, Edward D., Remaley, Alan T., Fredrickson, Donald S., Brewer, H. Bryan, Santamarina-Fojo, Silvia
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2002)
Published in Proceedings of the National Academy of Sciences - PNAS (08.01.2002)
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Journal Article
ABCA1 Overexpression in the Liver of LDLr-KO Mice Leads to Accumulation of Pro-atherogenic Lipoproteins and Enhanced Atherosclerosis
Joyce, Charles W., Wagner, Elke M., Basso, Federica, Amar, Marcelo J., Freeman, Lita A., Shamburek, Robert D., Knapper, Catherine L., Syed, Jafri, Wu, Justina, Vaisman, Boris L., Fruchart-Najib, Jamila, Billings, Eric M., Paigen, Beverly, Remaley, Alan T., Santamarina-Fojo, Silvia, Brewer, H. Bryan
Published in The Journal of biological chemistry (03.11.2006)
Published in The Journal of biological chemistry (03.11.2006)
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Journal Article
Insulin-Mediated Down-Regulation of Apolipoprotein A5 Gene Expression through the Phosphatidylinositol 3-Kinase Pathway: Role of Upstream Stimulatory Factor
Nowak, Maxime, Helleboid-Chapman, Audrey, Jakel, Heidelinde, Martin, Geneviève, Duran-Sandoval, Daniel, Staels, Bart, Rubin, Edward M., Pennacchio, Len A., Taskinen, Marja-Riitta, Fruchart-Najib, Jamila, Fruchart, Jean-Charles
Published in Molecular and Cellular Biology (01.02.2005)
Published in Molecular and Cellular Biology (01.02.2005)
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Journal Article
The Liver X Receptor Ligand T0901317 Down-regulates APOA5 Gene Expression through Activation of SREBP-1c
Jakel, Heidelinde, Nowak, Maxime, Moitrot, Emanuelle, Dehondt, Hélène, Hum, Dean W, Pennacchio, Len A, Fruchart-Najib, Jamila, Fruchart, Jean-Charles
Published in The Journal of biological chemistry (29.10.2004)
Published in The Journal of biological chemistry (29.10.2004)
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Journal Article
Cholesteryl ester transfer protein corrects dysfunctional high density lipoproteins and reduces aortic atherosclerosis in lecithin cholesterol acyltransferase transgenic mice
Foger, B, Chase, M, Amar, M.J, Vaisman, B.L, Shamburek, R.D, Paigen, B, Fruchart-Najib, J, Paiz, J.A, Koch, C.A, Hoyt, R.F
Published in The Journal of biological chemistry (24.12.1999)
Published in The Journal of biological chemistry (24.12.1999)
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Journal Article
Alterations of plasma lipids in mice via adenoviral-mediated hepatic overexpression of human ABCA1
Wellington, Cheryl L., Brunham, Liam R., Zhou, Steven, Singaraja, Roshni R., Visscher, Henk, Gelfer, Allison, Ross, Colin, James, Erick, Liu, Guoqing, Huber, Mary T., Yang, Yu-Zhou, Parks, Robin J., Groen, Albert, Fruchart-Najib, Jamila, Hayden, Michael R.
Published in Journal of lipid research (01.08.2003)
Published in Journal of lipid research (01.08.2003)
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Journal Article
Postprandial increase of plasma apoAV concentrations in Type 2 diabetic patients
Pruneta-Deloche, Valérie, Ponsin, Gabriel, Groisne, Laure, Fruchart-Najib, Jamila, Lagarde, Michel, Moulin, Philippe
Published in Atherosclerosis (01.08.2005)
Published in Atherosclerosis (01.08.2005)
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Journal Article
Glucose regulates LXRα subcellular localization and function in rat pancreatic β-cells
Helleboid-Chapman, Audrey, Helleboid, Stéphane, Jakel, Heidelinde, Timmerman, Catherine, Sergheraert, Christian, Pattou, François, Fruchart-Najib, Jamila, Fruchart, Jean-Charles
Published in Cell research (01.07.2006)
Published in Cell research (01.07.2006)
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Journal Article
The Ligand-binding Function of Hepatic Lipase Modulates the Development of Atherosclerosis in Transgenic Mice
Gonzalez-Navarro, Herminia, Nong, Zengxuan, Amar, Marcelo JA, Shamburek, Robert D, Najib-Fruchart, Jamila, Paigen, Beverly J, Brewer, HBryan, Santamarina-Fojo, Silvia
Published in The Journal of biological chemistry (29.10.2004)
Published in The Journal of biological chemistry (29.10.2004)
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Journal Article