Mimicking the cardiac cycle in intact cardiomyocytes using diastolic and systolic force clamps; measuring power output
Helmes, Michiel, Najafi, Aref, Palmer, Bradley M, Breel, Ernst, Rijnveld, Niek, Iannuzzi, Davide, van der Velden, Jolanda
Published in Cardiovascular research (01.07.2016)
Published in Cardiovascular research (01.07.2016)
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Journal Article
ADP-stimulated contraction: A predictor of thin-filament activation in cardiac disease
Sequeira, Vasco, Najafi, Aref, Wijnker, Paul J. M., dos Remedios, Cristobal G., Michels, Michelle, Kuster, Diederik W. D., van der Velden, Jolanda
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.2015)
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Journal Article
A novel method of measuring electrophoretic mobility of gas bubbles
Najafi, Aref Seyyed, Drelich, Jaroslaw, Yeung, Anthony, Xu, Zhenghe, Masliyah, Jacob
Published in Journal of colloid and interface science (15.04.2007)
Published in Journal of colloid and interface science (15.04.2007)
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Journal Article
Single micro-bubble generation by pressure pulse technique
Najafi, Aref Seyyed, Xu, Zhenghe, Masliyah, Jacob
Published in Chemical engineering science (01.04.2008)
Published in Chemical engineering science (01.04.2008)
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Journal Article
Right Ventricular Myocardial Stiffness in Experimental Pulmonary Arterial Hypertension: Relative Contribution of Fibrosis and Myofibril Stiffness
Rain, Silvia, Andersen, Stine, Najafi, Aref, Gammelgaard Schultz, Jacob, da Silva Gonçalves Bós, Denielli, Handoko, M Louis, Bogaard, Harm-Jan, Vonk-Noordegraaf, Anton, Andersen, Asger, van der Velden, Jolanda, Ottenheijm, Coen A C, de Man, Frances S
Published in Circulation. Heart failure (01.07.2016)
Published in Circulation. Heart failure (01.07.2016)
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Journal Article
Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy With Missense Sarcomeric Gene Mutations
Sequeira, Vasco, Wijnker, Paul J.M, Nijenkamp, Louise L.A.M, Kuster, Diederik W.D, Najafi, Aref, Witjas-Paalberends, E Rosalie, Regan, Jessica A, Boontje, Nicky, ten Cate, Folkert J, Germans, Tjeerd, Carrier, Lucie, Sadayappan, Sakthivel, van Slegtenhorst, Marjon A, Zaremba, Ruud, Foster, D Brian, Murphy, Anne M, Poggesi, Corrado, dos Remedios, Cris, Stienen, Ger J.M, Ho, Carolyn Y, Michels, Michelle, van der Velden, Jolanda
Published in Circulation research (24.05.2013)
Published in Circulation research (24.05.2013)
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Journal Article
Synergistic role of ADP and Ca(2+) in diastolic myocardial stiffness
Sequeira, Vasco, Najafi, Aref, McConnell, Mark, Fowler, Ewan D, Bollen, Ilse A E, Wüst, Rob C I, dos Remedios, Cris, Helmes, Michiel, White, Ed, Stienen, Ger J M, Tardiff, Jil, Kuster, Diederik W D, van der Velden, Jolanda
Published in The Journal of physiology (01.09.2015)
Published in The Journal of physiology (01.09.2015)
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Journal Article
The Power Output of Intact, Isolated Rat Cardiomyocytes
Helmes, Michiel, Najafi, Aref, van der Velden, Jolanda
Published in Biophysical journal (27.01.2015)
Published in Biophysical journal (27.01.2015)
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Journal Article
Synergistic role of ADP and Ca2+ in diastolic myocardial stiffness
Sequeira, Vasco, Najafi, Aref, McConnell, Mark, Fowler, Ewan D., Bollen, Ilse A. E., Wüst, Rob C. I., dos Remedios, Cris, Helmes, Michiel, White, Ed, Stienen, Ger J. M., Tardiff, Jil, Kuster, Diederik W. D., der Velden, Jolanda
Published in The Journal of physiology (01.09.2015)
Published in The Journal of physiology (01.09.2015)
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Journal Article
In vitro model to study the effects of matrix stiffening on Ca2+ handling and myofilament function in isolated adult rat cardiomyocytes
Deel, Elza D., Najafi, Aref, Fontoura, Dulce, Valent, Erik, Goebel, Max, Kardux, Kim, Falcão‐Pires, Inês, Velden, Jolanda
Published in The Journal of physiology (15.07.2017)
Published in The Journal of physiology (15.07.2017)
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Journal Article
End‐diastolic force pre‐activates cardiomyocytes and determines contractile force: role of titin and calcium
Najafi, Aref, de Locht, Martijn, Schuldt, Maike, Schönleitner, Patrick, Willigenburg, Menne, Bollen, Ilse, Goebel, Max, Ottenheijm, Coen A. C., der Velden, Jolanda, Helmes, Michiel, Kuster, Diederik W. D.
Published in The Journal of physiology (01.09.2019)
Published in The Journal of physiology (01.09.2019)
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Journal Article
In vitro model to study the effects of matrix stiffening on Ca 2+ handling and myofilament function in isolated adult rat cardiomyocytes
van Deel, Elza D, Najafi, Aref, Fontoura, Dulce, Valent, Erik, Goebel, Max, Kardux, Kim, Falcão-Pires, Inês, van der Velden, Jolanda
Published in The Journal of physiology (15.07.2017)
Published in The Journal of physiology (15.07.2017)
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Journal Article
Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model
Najafi, Aref, Sequeira, Vasco, Helmes, Michiel, Bollen, Ilse A E, Goebel, Max, Regan, Jessica A, Carrier, Lucie, Kuster, Diederik W D, Van Der Velden, Jolanda
Published in Cardiovascular research (15.05.2016)
Published in Cardiovascular research (15.05.2016)
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Journal Article
Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function
van Dijk, Sabine J, Paalberends, E Rosalie, Najafi, Aref, Michels, Michelle, Sadayappan, Sakthivel, Carrier, Lucie, Boontje, Nicky M, Kuster, Diederik W D, van Slegtenhorst, Marjon, Dooijes, Dennis, dos Remedios, Cris, ten Cate, Folkert J, Stienen, Ger J M, van der Velden, Jolanda
Published in Circulation. Heart failure (01.01.2012)
Published in Circulation. Heart failure (01.01.2012)
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Journal Article
Pre-Activation of Cardiomyocytes Determines Speed of Contraction: Role of Titin
Helmes, Michiel, Najafi, Aref, van der Locht, Martijn, Schuldt, Maike, Bollen, Ilse AE, Goebel, Max, Ottenheijm, Coen, van der Velden, Jolanda, Kuster, Diederik WD
Published in Biophysical journal (03.02.2017)
Published in Biophysical journal (03.02.2017)
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Journal Article
GSK3β Phosphorylates Newly Identified Site in the Proline-Alanine–Rich Region of Cardiac Myosin–Binding Protein C and Alters Cross-Bridge Cycling Kinetics in Human: Short Communication
Kuster, Diederik W D, Sequeira, Vasco, Najafi, Aref, Boontje, Nicky M, Wijnker, Paul J M, Witjas-Paalberends, E Rosalie, Marston, Steven B, dos Remedios, Cristobal G, Carrier, Lucie, Demmers, Jeroen A A, Redwood, Charles, Sadayappan, Sakthivel, van der Velden, Jolanda
Published in Circulation research (15.02.2013)
Published in Circulation research (15.02.2013)
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Journal Article