571 IL-2 combination with ImmTAC overcomes CD163+ TAM-like M2 macrophage inhibition of ImmTAC-mediated T cell killing of tumor cells
Khanolkar, Rahul, Naidoo, Revashnee, Güç, Esra, Leach, Emma, Stanhope, Sarah, Gascoyne, Duncan, Collins, Laura, Ranade, Koustubh, Benlahrech, Adel
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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Tebentafusp, A TCR/Anti-CD3 Bispecific Fusion Protein Targeting gp100, Potently Activated Antitumor Immune Responses in Patients with Metastatic Melanoma
Middleton, Mark R, McAlpine, Cheryl, Woodcock, Victoria K, Corrie, Pippa, Infante, Jeffrey R, Steven, Neil M, Evans, Thomas R Jeffry, Anthoney, Alan, Shoushtari, Alexander N, Hamid, Omid, Gupta, Avinash, Vardeu, Antonella, Leach, Emma, Naidoo, Revashnee, Stanhope, Sarah, Lewis, Sion, Hurst, Jacob, O'Kelly, Ita, Sznol, Mario
Published in Clinical cancer research (15.11.2020)
Published in Clinical cancer research (15.11.2020)
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Abstract 1673: Uveal melanoma study patients with low CD163:CD3 ratio in tumor biopsy and low serum IL-6 showed enhanced tumor shrinkage (TS) and overall survival (OS) on tebentafusp
Hassel, Jessica C., Benlahrech, Adel, Stanhope, Sarah, Naidoo, Revashnee, Leach, Emma, Collins, Laura, Abdullah, Shaad, Ranade, Koustubh, Sacco, Joseph
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 517: Tebentafusp induces transient systemic inflammation and modifies the micro-environment to sensitize uveal melanoma tumors to cytotoxic CD8 cells
Butler, Marcus O., Stanhope, Sarah, Naidoo, Revashnee, Leach, Emma, Kaur, Sarnjeet, Collins, Laura, Abdullah, Shaad, Ranade, Koustubh, Shoushtari, Alexander N.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Autologous T cell therapy for MAGE-A4 + solid cancers in HLA-A02 + patients: a phase 1 trial
Hong, David S, Van Tine, Brian A, Biswas, Swethajit, McAlpine, Cheryl, Johnson, Melissa L, Olszanski, Anthony J, Clarke, Jeffrey M, Araujo, Dejka, Blumenschein, Jr, George R, Kebriaei, Partow, Lin, Quan, Tipping, Alex J, Sanderson, Joseph P, Wang, Ruoxi, Trivedi, Trupti, Annareddy, Thejo, Bai, Jane, Rafail, Stavros, Sun, Amy, Fernandes, Lilliam, Navenot, Jean-Marc, Bushman, Frederic D, Everett, John K, Karadeniz, Derin, Broad, Robyn, Isabelle, Martin, Naidoo, Revashnee, Bath, Natalie, Betts, Gareth, Wolchinsky, Zohar, Batrakou, Dzmitry G, Van Winkle, Erin, Elefant, Erica, Ghobadi, Armin, Cashen, Amanda, Grand'Maison, Anne, McCarthy, Philip, Fracasso, Paula M, Norry, Elliot, Williams, Dennis, Druta, Mihaela, Liebner, David A, Odunsi, Kunle, Butler, Marcus O
Published in Nature medicine (01.01.2023)
Published in Nature medicine (01.01.2023)
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2022-LBA-414-ESGO Preliminary clinical outcome of ADP-A2M4CD8, a next-generation autologous T-cell receptor T-cell therapy, in patients with advanced epithelial ovarian cancer
Moore, Kathleen, Asch, Adam, Moreno, Victor, Calvo, Emiliano, Butler, Marcus, Zugazagoitia, Jon, Hong, David, Galal, Ahmed, Ostios, Lorena, de Miguel, Maria, Lin, Quan, Annareddy, Thejo, Brophy, Francine, Rosenberg, Marisa, Seiders, Theresa, Naidoo, Revashnee, Bath, Natalie, Saro, Jose, Norry, Elliot, Clarke, Jeffrey
Published in International journal of gynecological cancer (27.10.2022)
Published in International journal of gynecological cancer (27.10.2022)
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A TCR/anti-CD3 bispecific fusion protein targeting gp100 potently activated anti-tumor immune responses in metastatic melanoma
Middleton, Mark R., McAlpine, Cheryl, Woodcock, Victoria K., Corrie, Pippa, Infante, Jeffry R., Steven, Neil Mathew, Evans, Thomas R Jeffry, Anthoney, Alan, Shoushtari, Alexander Noor, Hamid, Omid, Gupta, Avinash, Vardeu, Antonella, Leach, Emma, Naidoo, Revashnee, Stanhope, Sarah, Lewis, Sion, Hurst, Jacob, O’Kelly, Ita, Sznol, Mario
Published in Clinical cancer research (18.08.2020)
Published in Clinical cancer research (18.08.2020)
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Abstract 892: Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4) demonstrates durable clinical responses by inducing broad immune engagement with anti-tumor activity
McAlpine, Cheryl, Isabelle, Martin, Broad, Robyn, Naidoo, Revashnee, Liddle, Ashley, Duperret, Elizabeth, Noto, Paul, Wang, Ruoxi, Batrakou, Dzmitry, Middha, Sumit, Evans, Chris
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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