Single Cell Analysis and Temporal Profiling of Agonist-mediated Inositol 1,4,5-Trisphosphate, Ca2+, Diacylglycerol, and Protein Kinase C Signaling using Fluorescent Biosensors
Bartlett, Paula J., Young, Kenneth W., Nahorski, Stefan R., Challiss, R. A. John
Published in The Journal of biological chemistry (10.06.2005)
Published in The Journal of biological chemistry (10.06.2005)
Get full text
Journal Article
Functional Selectivity of Muscarinic Receptor Antagonists for Inhibition of M3-Mediated Phosphoinositide Responses in Guinea Pig Urinary Bladder and Submandibular Salivary Gland
Nelson, Carl P, Gupta, Paul, Napier, Carolyn M, Nahorski, Stefan R, Challiss, R A John
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)
Get full text
Journal Article
Roles of Phosphorylation-dependent and -independent Mechanisms in the Regulation of M1 Muscarinic Acetylcholine Receptors by G Protein-coupled Receptor Kinase 2 in Hippocampal Neurons
Willets, Jonathon M., Nahorski, Stefan R., Challiss, R. A. John
Published in The Journal of biological chemistry (13.05.2005)
Published in The Journal of biological chemistry (13.05.2005)
Get full text
Journal Article
Imaging of Muscarinic Acetylcholine Receptor Signaling in Hippocampal Neurons: Evidence for Phosphorylation-Dependent and -Independent Regulation by G-Protein-Coupled Receptor Kinases
Willets, Jonathon M, Nash, Mark S, Challiss, R. A. John, Nahorski, Stefan R
Published in The Journal of neuroscience (28.04.2004)
Published in The Journal of neuroscience (28.04.2004)
Get full text
Journal Article
Endogenous G Protein-coupled Receptor Kinase 6 Regulates M3 Muscarinic Acetylcholine Receptor Phosphorylation and Desensitization in Human SH-SY5Y Neuroblastoma Cells
Willets, Jonathon M., Challiss, R. A. John, Nahorski, Stefan R.
Published in The Journal of biological chemistry (03.05.2002)
Published in The Journal of biological chemistry (03.05.2002)
Get full text
Journal Article
Synaptic Activity Augments Muscarinic Acetylcholine Receptor-stimulated Inositol 1,4,5-Trisphosphate Production to Facilitate Ca2+ Release in Hippocampal Neurons
Nash, Mark S, Willets, Jonathon M, Billups, Brian, John Challiss, R A, Nahorski, Stefan R
Published in The Journal of biological chemistry (19.11.2004)
Published in The Journal of biological chemistry (19.11.2004)
Get full text
Journal Article
Specificity of G Protein-Coupled Receptor Kinase 6-Mediated Phosphorylation and Regulation of Single-Cell M3 Muscarinic Acetylcholine Receptor Signaling
Willets, Jonathon M, Mistry, Rajendra, Nahorski, Stefan R, Challiss, R A John
Published in Molecular pharmacology (01.11.2003)
Published in Molecular pharmacology (01.11.2003)
Get full text
Journal Article
A Single Point Mutation (N514Y) in the Human M3 Muscarinic Acetylcholine Receptor Reveals Differences in the Properties of Antagonists: Evidence for Differential Inverse Agonism
Dowling, Mark R, Willets, Jonathon M, Budd, David C, Charlton, Steven J, Nahorski, Stefan R, Challiss, R A John
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2006)
Get full text
Journal Article
New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor
Wilcox, Robert A, Primrose, William U, Nahorski, Stefan R, Challiss, R.A.John
Published in Trends in Pharmacological Sciences (01.11.1998)
Published in Trends in Pharmacological Sciences (01.11.1998)
Get full text
Book Review
Journal Article
Non-visual GRKs: are we seeing the whole picture?
Willets, Jonathon M., Challiss, R.A.John, Nahorski, Stefan R.
Published in Trends in pharmacological sciences (Regular ed.) (01.12.2003)
Published in Trends in pharmacological sciences (Regular ed.) (01.12.2003)
Get full text
Journal Article
Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated signalling in single neurons
Nelson, Carl P, Nahorski, Stefan R, Challiss, R.A. John
Published in Journal of neurochemistry (01.11.2008)
Published in Journal of neurochemistry (01.11.2008)
Get full text
Journal Article
Temporal profiling of changes in phosphatidylinositol 4,5‐bisphosphate, inositol 1,4,5‐trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C‐initiated signalling in single neurons1
Nelson, Carl P., Nahorski, Stefan R., Challiss, R. A. John
Published in Journal of neurochemistry (01.11.2008)
Published in Journal of neurochemistry (01.11.2008)
Get full text
Journal Article
Neuronal Ca2+ stores : activation and function
SIMPSON, P. B, CHALLISS, R. A. J, NAHORSKI, S. R
Published in Trends in neurosciences (Regular ed.) (01.07.1995)
Published in Trends in neurosciences (Regular ed.) (01.07.1995)
Get full text
Journal Article
Characterization of an atypical muscarinic cholinoceptor mediating contraction of the guinea‐pig isolated uterus
Boxall, Donna K, Ford, Anthony P D W, Choppin, Agnes, Nahorski, Stefan R, Challiss, R A John, Eglen, Richard M
Published in British journal of pharmacology (01.08.1998)
Published in British journal of pharmacology (01.08.1998)
Get full text
Journal Article