A novel rhodopsin phosphodiesterase from Salpingoeca rosetta shows light-enhanced substrate affinity
Tian, Yuehui, Gao, Shiqiang, Yang, Shang, Nagel, Georg
Published in Biochemical journal (30.03.2018)
Published in Biochemical journal (30.03.2018)
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Structural Guidance of the Photocycle of Channelrhodopsin-2 by an Interhelical Hydrogen Bond
Bamann, Christian, Gueta, Ronnie, Kleinlogel, Sonja, Nagel, Georg, Bamberg, Ernst
Published in Biochemistry (Easton) (19.01.2010)
Published in Biochemistry (Easton) (19.01.2010)
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Channelrhodopsin-2–XXL, a powerful optogenetic tool for low-light applications
Dawydow, Alexej, Gueta, Ronnie, Ljaschenko, Dmitrij, Ullrich, Sybille, Hermann, Moritz, Ehmann, Nadine, Gao, Shiqiang, Fiala, André, Langenhan, Tobias, Nagel, Georg, Kittel, Robert J.
Published in Proceedings of the National Academy of Sciences - PNAS (23.09.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (23.09.2014)
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Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp
Gao, Shiqiang, Nagpal, Jatin, Schneider, Martin W, Kozjak-Pavlovic, Vera, Nagel, Georg, Gottschalk, Alexander
Published in Nature communications (08.09.2015)
Published in Nature communications (08.09.2015)
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Light Modulation of Cellular cAMP by a Small Bacterial Photoactivated Adenylyl Cyclase, bPAC, of the Soil Bacterium Beggiatoa
Stierl, Manuela, Stumpf, Patrick, Udwari, Daniel, Gueta, Ronnie, Hagedorn, Rolf, Losi, Aba, Gärtner, Wolfgang, Petereit, Linda, Efetova, Marina, Schwarzel, Martin, Oertner, Thomas G., Nagel, Georg, Hegemann, Peter
Published in The Journal of biological chemistry (14.01.2011)
Published in The Journal of biological chemistry (14.01.2011)
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Spatially asymmetric reorganization of inhibition establishes a motion-sensitive circuit
YONEHARA, Keisuke, BALINT, Kamill, NODA, Masaharu, NAGEL, Georg, BAMBERG, Ernst, ROSKA, Botond
Published in Nature (London) (20.01.2011)
Published in Nature (London) (20.01.2011)
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Channelrhodopsin-mediated optogenetics highlights a central role of depolarization-dependent plant proton pumps
Reyer, Antonella, Häßler, Melanie, Scherzer, Sönke, Huang, Shouguang, Pedersen, Jesper Torbøl, Al-Rascheid, Khaled A. S., Bamberg, Ernst, Palmgren, Michael, Dreyer, Ingo, Nagel, Georg, Hedrich, Rainer, Becker, Dirk
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2020)
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Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain
Scheib, Ulrike, Broser, Matthias, Constantin, Oana M, Yang, Shang, Gao, Shiqiang, Mukherjee, Shatanik, Stehfest, Katja, Nagel, Georg, Gee, Christine E, Hegemann, Peter
Published in Nature communications (24.05.2018)
Published in Nature communications (24.05.2018)
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PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression
Dörsam, Bastian, Seiwert, Nina, Foersch, Sebastian, Stroh, Svenja, Nagel, Georg, Begaliew, Diana, Diehl, Erika, Kraus, Alexander, McKeague, Maureen, Minneker, Vera, Roukos, Vassilis, Reißig, Sonja, Waisman, Ari, Moehler, Markus, Stier, Anna, Mangerich, Aswin, Dantzer, Françoise, Kaina, Bernd, Fahrer, Jörg
Published in Proceedings of the National Academy of Sciences - PNAS (24.04.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (24.04.2018)
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Optimized photo-stimulation of halorhodopsin for long-term neuronal inhibition
Zhang, Chuanqiang, Yang, Shang, Flossmann, Tom, Gao, Shiqiang, Witte, Otto W, Nagel, Georg, Holthoff, Knut, Kirmse, Knut
Published in BMC biology (27.11.2019)
Published in BMC biology (27.11.2019)
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Structural basis of TRPC4 regulation by calmodulin and pharmacological agents
Vinayagam, Deivanayagabarathy, Quentin, Dennis, Yu-Strzelczyk, Jing, Sitsel, Oleg, Merino, Felipe, Stabrin, Markus, Hofnagel, Oliver, Yu, Maolin, Ledeboer, Mark W, Nagel, Georg, Malojcic, Goran, Raunser, Stefan
Published in eLife (25.11.2020)
Published in eLife (25.11.2020)
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Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons
Scholz, Nicole, Guan, Chonglin, Nieberler, Matthias, Grotemeyer, Alexander, Maiellaro, Isabella, Gao, Shiqiang, Beck, Sebastian, Pawlak, Matthias, Sauer, Markus, Asan, Esther, Rothemund, Sven, Winkler, Jana, Prömel, Simone, Nagel, Georg, Langenhan, Tobias, Kittel, Robert J
Published in eLife (08.08.2017)
Published in eLife (08.08.2017)
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A LOV-domain-mediated blue-light-activated adenylate (adenylyl) cyclase from the cyanobacterium Microcoleus chthonoplastes PCC 7420
Raffelberg, Sarah, Wang, Linzhu, Gao, Shiqiang, Losi, Aba, Gärtner, Wolfgang, Nagel, Georg
Published in Biochemical journal (01.11.2013)
Published in Biochemical journal (01.11.2013)
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MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma
Christmann, Markus, Nagel, Georg, Horn, Sigrid, Krahn, Ulrike, Wiewrodt, Dorothee, Sommer, Clemens, Kaina, Bernd
Published in International journal of cancer (01.11.2010)
Published in International journal of cancer (01.11.2010)
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Two-component cyclase opsins of green algae are ATP-dependent and light-inhibited guanylyl cyclases
Tian, Yuehui, Gao, Shiqiang, von der Heyde, Eva Laura, Hallmann, Armin, Nagel, Georg
Published in BMC biology (06.12.2018)
Published in BMC biology (06.12.2018)
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Channelrhodopsin-2, a directly light-gated cation-selective membrane channel
Nagel, G, Szellas, T, Huhn, W, Kateriya, S, Adeishvili, N, Berthold, P, Ollig, D, Hegemann, P, Bamberg, E
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (25.11.2003)
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Tailoring baker's yeast Saccharomyces cerevisiae for functional testing of channelrhodopsin
Höler, Sebastian, Degreif, Daniel, Stix, Florentine, Yang, Shang, Gao, Shiqiang, Nagel, Georg, Moroni, Anna, Thiel, Gerhard, Bertl, Adam, Rauh, Oliver
Published in PloS one (13.04.2023)
Published in PloS one (13.04.2023)
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