Use of determinations of 7-lathosterol (5α-cholest-7-en-3β-ol) and other cholesterol precursors in serum in the study and treatment of disturbances of sterol metabolism, particularly cerebrotendinous xanthomatosis
WOLTHERS, B. G, WALRECHT, H. T, VAN DER MOLEN, J. C, NAGEL, G. T, VAN DOORMAAL, J. J, WIJNANDTS, P. N
Published in Journal of lipid research (01.04.1991)
Published in Journal of lipid research (01.04.1991)
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Phenylketonuria. The in vivo hydroxylation rate of phenylalanine into tyrosine is decreased
van Spronsen, F J, Reijngoud, D J, Smit, G P, Nagel, G T, Stellaard, F, Berger, R, Heymans, H S
Published in The Journal of clinical investigation (15.06.1998)
Published in The Journal of clinical investigation (15.06.1998)
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Oral administration of deuterium-labelled polyamines to sucking rat pups: luminal uptake, metabolic fate and effects on gastrointestinal maturation
Dorhout, Bernard, Van Faassen, Anet, Van Beusekom, Christien M., Kingma, Anneke W., De Hoog, Elly, Nagel, Gijs T., Karrenbeld, Arend, Boersma, E. Rudy, Muskiet, Frits A. J.
Published in British journal of nutrition (01.10.1997)
Published in British journal of nutrition (01.10.1997)
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Optimization of a classical aromatase activity assay and application in normal, adenomatous and malignant breast parenchyma
Dikkeschei, L.D., Wolthers, B.G., Bos-Zuur, I., de la Rivière, G.Brutel, Nagel, G.T., van der Kolk, D.A., Willemse, P.H.B.
Published in The Journal of steroid biochemistry and molecular biology (01.11.1996)
Published in The Journal of steroid biochemistry and molecular biology (01.11.1996)
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Journal Article
New identified 15β-hydroxylated 21-deoxy-pregnanes in congenital adrenal hyperplasia due to 21-hydroxylase deficiency
KRAAN, G. P. B, WOLTHERS, B. G, VAN DER MOLEN, J. C, NAGEL, G. T, DRAYER, N. M, JOANNOU, G. E
Published in The Journal of steroid biochemistry and molecular biology (01.05.1993)
Published in The Journal of steroid biochemistry and molecular biology (01.05.1993)
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Urinary steroid profile of a newborn suffering from pseudohypoaldosteronism
Wolthers, B.G., Kraan, G.P.B., van der Molen, J.C., Nagel, G.T., Rouwe, C.W., Lenting, F., Boersma, E.R.
Published in Clinica chimica acta (30.04.1995)
Published in Clinica chimica acta (30.04.1995)
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The determination of delta-5-androstenediol and its sulphate in serum and urine by gas chromatography-mass spectrometry
Dikkeschei, L D, Wolthers, B G, Willemse, P H, van der Pol, H, de Ruyter-Buitenhuis, A W, Nagel, G T
Published in Clinical endocrinology (Oxford) (01.10.1993)
Published in Clinical endocrinology (Oxford) (01.10.1993)
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Synthesis and identification of twelve A-ring reduced 6α- and 6β-hydroxylated compounds derived from 11-deoxycortisol, corticosterone and 11-dehydrocorticosterone
Kraan, G.P.B., Hartstra, J., Wolthers, B.G., van der Molen, J.C., Nagel, G.T., Drayer, N.M., Zijlstra, R.W.J., Kruizinga, W.H.
Published in The Journal of steroid biochemistry and molecular biology (01.06.1994)
Published in The Journal of steroid biochemistry and molecular biology (01.06.1994)
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Measurement of short-chain acyl-CoA dehydrogenase (SCAD) in cultured skin fibroblasts with hexanoyl-CoA as a competitive inhibitor to eliminate the contribution of medium-chain acyl-CoA dehydrogenase
Niezen-Koning, Klary E., Wanders, Ronald J.A., Nagel, Gijs T., Sewell, Adrian C., Heymans, Hugo S.A.
Published in Clinica chimica acta (01.09.1994)
Published in Clinica chimica acta (01.09.1994)
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Detection of 3β-hydroxysteroid dehydrogenase deficiency in a newborn by means of urinary steroid analysis
Wolthers, B.G., de Vries, I.J., Volmer, M., Nagel, G.T.
Published in Clinica chimica acta (30.10.1987)
Published in Clinica chimica acta (30.10.1987)
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GC-MS determination of ratios of stable-isotope labelled to natural urea using [ 13C 15N 2]urea for studying urea kinetics in serum and as a means to validate routine methods for the quantitative assay of urea in dialysate
Wolthers, B.G., Tepper, T., Withag, A., Nagel, G.T., Haan, T.H.Y.de, Leeuwen, J.J.van, Stegeman, C.A., Huisman, R.M.
Published in Clinica chimica acta (01.02.1994)
Published in Clinica chimica acta (01.02.1994)
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Determination of cholic acid and chenodeoxycholic acid pool sizes and fractional turnover rates by means of stable isotope dilution technique, making use of deuterated cholic acid and chenodeoxycholic acid
Koopman, B.J., Kuipers, F., Bijleveld, C.M.A., Van Der Molen, J.C., Nagel, G.T., Vonk, R.J., Wolthers, B.G.
Published in Clinica chimica acta (15.07.1988)
Published in Clinica chimica acta (15.07.1988)
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Capillary gas chromatographic determinations of urinary bile acids and bile alcohols in CTX patients proving the ineffectivity of ursodeoxycholic acid treatment
Koopman, B.J., Wolthers, B.G., van der Molen, J.C., Nagel, G.T., Waterreus, R.J., Oosterhuis, H.J.G.H.
Published in Clinica chimica acta (15.09.1984)
Published in Clinica chimica acta (15.09.1984)
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Increased (23 R)-hydroxylase activity in patients suffering from cerebrotendinous xanthomatosis, resulting in (23 R)-hydroxylation of bile acids
Koopman, B.J., Wolthers, B.G., Van der Molen, J.C., Nagel, G.T., Rutgers, H., Strijtveen, B., Kaptein, B.
Published in Biochimica et biophysica acta (01.10.1986)
Published in Biochimica et biophysica acta (01.10.1986)
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Abnormal urinary bile acids in a patient suffering from cerebrotendinous xanthomatosis during oral administration of ursodeoxycholic acid
Koopman, B.J., Wolthers, B.G., van der Molen, J.C., Nagel, G.T., Kruizinga, W.
Published in Biochimica et biophysica acta (14.02.1987)
Published in Biochimica et biophysica acta (14.02.1987)
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Determination of the urinary cortisol production rate using (1,2,3,4-13C)cortisol. Isotope dilution analyses at very small enrichments
Chapman, T E, Kraan, G P, Drayer, N M, Nagel, G T, Wolthers, B G
Published in Biomedical & environmental mass spectrometry (01.02.1987)
Published in Biomedical & environmental mass spectrometry (01.02.1987)
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