Synthesis, molecular modeling and anti-cancer evaluation of a series of quinazoline derivatives
Khodair, Ahmed I., Alsafi, Mona A., Nafie, Mohamed S.
Published in Carbohydrate research (01.12.2019)
Published in Carbohydrate research (01.12.2019)
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Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies
Khalifa, Mohamed M., Al-Karmalawy, Ahmed A., Elkaeed, Eslam B., Nafie, Mohamed S., Tantawy, Mohamed A., Eissa, Ibrahim H., Mahdy, Hazem A.
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
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Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-Amino-4,5,6,7-Tetra Hydrobenzo[ b ]Thiophene-3-Carboxylate: Synthesis, In Vitro, and In Vivo Activity Evaluation
Gad, Emad M, Nafie, Mohamed S, Eltamany, Elsayed H, Hammad, Magdy S A G, Barakat, Assem, Boraei, Ahmed T A
Published in Molecules (Basel, Switzerland) (28.05.2020)
Published in Molecules (Basel, Switzerland) (28.05.2020)
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Design and synthesis of novel rigid dibenzo[b,f]azepines through ring closure technique as promising anticancer candidates against leukaemia and acting as selective topoisomerase II inhibitors and DNA intercalators
El-Behairy, Mohammed Farrag, Abd-Allah, Walaa Hamada, Khalifa, Mohamed M., Nafie, Mohamed S., Saleh, Mohamed A., Abdel-Maksoud, Mohammed S., Al-Warhi, Tarfah, Eldehna, Wagdy M., Al-Karmalawy, Ahmed A.
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
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Novel bis -amide-based bis-thiazoles as Anti-colorectal Cancer Agents Through Bcl-2 Inhibition: Synthesis, In Vitro , and In Vivo studies
Dawood, Kamal M, Raslan, Mohamed A, Abbas, Ashraf A, Mohamed, Belal E, Nafie, Mohamed S
Published in Anti-cancer agents in medicinal chemistry (01.01.2023)
Published in Anti-cancer agents in medicinal chemistry (01.01.2023)
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Molecular Insights into Human Transmembrane Protease Serine-2 (TMPS2) Inhibitors against SARS-CoV2: Homology Modelling, Molecular Dynamics, and Docking Studies
Kishk, Safaa M, Kishk, Rania M, Yassen, Asmaa S A, Nafie, Mohamed S, Nemr, Nader A, ElMasry, Gamal, Al-Rejaie, Salim, Simons, Claire
Published in Molecules (Basel, Switzerland) (29.10.2020)
Published in Molecules (Basel, Switzerland) (29.10.2020)
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Metabolite profiling and in-silico studies show multiple effects of insecticidal actinobacterium on Spodoptera littoralis
Diab, Mohamed Khaled, Mead, Hala Mohamed, Khedr, Mohamad Ahmad, Nafie, Mohamed S., Abu-Elsaoud, Abdelghafar Mohamed, El-Shatoury, Sahar Ahmed
Published in Scientific reports (06.02.2024)
Published in Scientific reports (06.02.2024)
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Structure Activity Relationship and Molecular Docking of Some Quinazolines Bearing Sulfamerazine Moiety as New 3CLpro, cPLA2, sPLA2 Inhibitors
Hussein, Mohammed Abdalla, Borik, Rita M, Nafie, Mohamed S, Abo-Salem, Heba M, Boshra, Sylvia A, Mohamed, Zahraa N
Published in Molecules (Basel, Switzerland) (01.08.2023)
Published in Molecules (Basel, Switzerland) (01.08.2023)
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2‐Phenylquinazolin‐4(3H)‐one scaffold as newly designed, synthesized VEGFR‐2 allosteric inhibitors with potent cytotoxicity through apoptosis
Elrayess, Ranza, Elgawish, Mohamed S., Nafie, Mohamed S., Ghareb, Nagat, Yassen, Asmaa S. A.
Published in Archiv der Pharmazie (Weinheim) (01.06.2023)
Published in Archiv der Pharmazie (Weinheim) (01.06.2023)
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Design, synthesis and antiproliferative activity of new amine, amino acid and dipeptide-coupled benzamides as potential sigma-1 receptor
Youssef, Eman, El-Moneim, Mohamed Abd, Fathalla, Walid, Nafie, Mohamed S.
Published in Journal of the Iranian Chemical Society (01.10.2020)
Published in Journal of the Iranian Chemical Society (01.10.2020)
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Design, synthesis, molecular modelling and antitumor evaluation of S-glucosylated rhodanines through topo II inhibition and DNA intercalation
Khodair, Ahmed I., Alzahrani, Fatimah M., Awad, Mohamed K., Al-Issa, Siham A., Al-Hazmi, Ghaferah H., Nafie, Mohamed S.
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
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Design and Synthesis of Coumarin Derivatives as Cytotoxic Agents through PI3K/AKT Signaling Pathway Inhibition in HL60 and HepG2 Cancer Cells
Kishk, Safaa M, Eltamany, Enas E, Nafie, Mohamed S, Khinkar, Roaa M, Hareeri, Rawan H, Elhady, Sameh S, Yassen, Asmaa S. A
Published in Molecules (Basel, Switzerland) (01.10.2022)
Published in Molecules (Basel, Switzerland) (01.10.2022)
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Evaluation of 2-Thioxoimadazolidin-4-one Derivatives as Potent Anti-Cancer Agents through Apoptosis Induction and Antioxidant Activation: In Vitro and In Vivo Approaches
Nafie, Mohamed S, Khodair, Ahmed I, Hassan, Hebat Allah Y, El-Fadeal, Noha M Abd, Bogari, Hanin A, Elhady, Sameh S, Ahmed, Safwat A
Published in Molecules (Basel, Switzerland) (23.12.2021)
Published in Molecules (Basel, Switzerland) (23.12.2021)
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Facile Synthesis of Some Coumarin Derivatives and Their Cytotoxicity through VEGFR2 and Topoisomerase II Inhibition
Gomaa, Mohamed S, Ali, Ibrahim A I, El Enany, Gaber, El Ashry, El Sayed H, El Rayes, Samir M, Fathalla, Walid, Ahmed, Abdulghany H A, Abubshait, Samar A, Abubshait, Haya A, Nafie, Mohamed S
Published in Molecules (Basel, Switzerland) (28.11.2022)
Published in Molecules (Basel, Switzerland) (28.11.2022)
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New spiro-indeno[1,2-b]quinoxalines clubbed with benzimidazole scaffold as CDK2 inhibitors for halting non-small cell lung cancer; stereoselective synthesis, molecular dynamics and structural insights
Barakat, Assem, Alshahrani, Saeed, Al-Majid, Abdullah Mohammed, Alamary, Abdullah Saleh, Haukka, Matti, Abu-Serie, Marwa M., Domingo, Luis R., Ashraf, Sajda, Ul-Haq, Zaheer, Nafie, Mohamed S., Teleb, Mohamed
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
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Silver Nanoparticles Formulation of Flower Head’s Polyphenols of Cynara scolymus L.: A Promising Candidate against Prostate (PC-3) Cancer Cell Line through Apoptosis Activation
Khedr, Amgad I. M., Goda, Marwa S., Farrag, Abdelaziz F. S., Nasr, Ali M., Swidan, Shady A., Nafie, Mohamed S., Abdel-Kader, Maged S., Badr, Jihan M., Abdelhameed, Reda F. A.
Published in Molecules (Basel, Switzerland) (24.09.2022)
Published in Molecules (Basel, Switzerland) (24.09.2022)
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