Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents
Mercey, Guillaume, Verdelet, Tristan, Renou, Julien, Kliachyna, Maria, Baati, Rachid, Nachon, Florian, Jean, Ludovic, Renard, Pierre-Yves
Published in Accounts of chemical research (15.05.2012)
Published in Accounts of chemical research (15.05.2012)
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Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study
Rosenberry, Terrone L, Brazzolotto, Xavier, Macdonald, Ian R, Wandhammer, Marielle, Trovaslet-Leroy, Marie, Darvesh, Sultan, Nachon, Florian
Published in Molecules (Basel, Switzerland) (29.11.2017)
Published in Molecules (Basel, Switzerland) (29.11.2017)
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A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides
Nachon, Florian, Rosenberry, Terrone L, Silman, Israel, Sussman, Joel L
Published in Molecules (Basel, Switzerland) (06.03.2020)
Published in Molecules (Basel, Switzerland) (06.03.2020)
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Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease
Chalupova, Katarina, Korabecny, Jan, Bartolini, Manuela, Monti, Barbara, Lamba, Doriano, Caliandro, Rosanna, Pesaresi, Alessandro, Brazzolotto, Xavier, Gastellier, Anne-Julie, Nachon, Florian, Pejchal, Jaroslav, Jarosova, Michaela, Hepnarova, Vendula, Jun, Daniel, Hrabinova, Martina, Dolezal, Rafael, Zdarova Karasova, Jana, Mzik, Martin, Kristofikova, Zdena, Misik, Jan, Muckova, Lubica, Jost, Petr, Soukup, Ondrej, Benkova, Marketa, Setnicka, Vladimir, Habartova, Lucie, Chvojkova, Marketa, Kleteckova, Lenka, Vales, Karel, Mezeiova, Eva, Uliassi, Elisa, Valis, Martin, Nepovimova, Eugenie, Bolognesi, Maria Laura, Kuca, Kamil
Published in European journal of medicinal chemistry (15.04.2019)
Published in European journal of medicinal chemistry (15.04.2019)
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Development of an in-vivo active reversible butyrylcholinesterase inhibitor
Košak, Urban, Brus, Boris, Knez, Damijan, Šink, Roman, Žakelj, Simon, Trontelj, Jurij, Pišlar, Anja, Šlenc, Jasna, Gobec, Martina, Živin, Marko, Tratnjek, Larisa, Perše, Martina, Sałat, Kinga, Podkowa, Adrian, Filipek, Barbara, Nachon, Florian, Brazzolotto, Xavier, Więckowska, Anna, Malawska, Barbara, Stojan, Jure, Raščan, Irena Mlinarič, Kos, Janko, Coquelle, Nicolas, Colletier, Jacques-Philippe, Gobec, Stanislav
Published in Scientific reports (21.12.2016)
Published in Scientific reports (21.12.2016)
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Diisopropylfluorophosphate-induced status epilepticus drives complex glial cell phenotypes in adult male mice
Maupu, Clémence, Enderlin, Julie, Igert, Alexandre, Oger, Myriam, Auvin, Stéphane, Hassan-Abdi, Rahma, Soussi-Yanicostas, Nadia, Brazzolotto, Xavier, Nachon, Florian, Dal Bo, Grégory, Dupuis, Nina
Published in Neurobiology of disease (01.05.2021)
Published in Neurobiology of disease (01.05.2021)
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Author Correction: Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal death
Brenet, Alexandre, Somkhit, Julie, Hassan-Abdi, Rahma, Yanicostas, Constantin, Romain, Christiane, Bar, Olivier, Igert, Alexandre, Saurat, Dominique, Taudon, Nicolas, Dal-Bo, Gregory, Nachon, Florian, Dupuis, Nina, Soussi-Yanicostas, Nadia
Published in Scientific reports (09.03.2021)
Published in Scientific reports (09.03.2021)
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A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning
Da Silva, Ophélie, Probst, Nicolas, Landry, Christophe, Hanak, Anne-Sophie, Warnault, Pierre, Coisne, Caroline, Calas, André-Guilhem, Gosselet, Fabien, Courageux, Charlotte, Gastellier, Anne-Julie, Trancart, Marilène, Baati, Rachid, Dehouck, Marie-Pierre, Jean, Ludovic, Nachon, Florian, Renard, Pierre-Yves, Dias, José
Published in Journal of medicinal chemistry (24.03.2022)
Published in Journal of medicinal chemistry (24.03.2022)
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Structural approach to the aging of phosphylated cholinesterases
Masson, Patrick, Nachon, Florian, Lockridge, Oksana
Published in Chemico-biological interactions (06.09.2010)
Published in Chemico-biological interactions (06.09.2010)
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Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal death
Brenet, Alexandre, Somkhit, Julie, Hassan-Abdi, Rahma, Yanicostas, Constantin, Romain, Christiane, Bar, Olivier, Igert, Alexandre, Saurat, Dominique, Taudon, Nicolas, Dal-Bo, Gregory, Nachon, Florian, Dupuis, Nina, Soussi-Yanicostas, Nadia
Published in Scientific reports (05.11.2020)
Published in Scientific reports (05.11.2020)
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Characterization of four BCHE mutations associated with prolonged effect of suxamethonium
Brazzolotto, Xavier, Courcelle, Sébastien, Sauvanet, Christophe, Guillon, Virginia, Igert, Alexandre, Kononchik, Joseph, Nachon, Florian, Ceppa, Franck, Delacour, Hervé
Published in The pharmacogenomics journal (01.04.2021)
Published in The pharmacogenomics journal (01.04.2021)
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Development of versatile and potent monoquaternary reactivators of acetylcholinesterase
Gorecki, Lukas, Hepnarova, Vendula, Karasova, Jana Zdarova, Hrabinova, Martina, Courageux, Charlotte, Dias, José, Kucera, Tomas, Kobrlova, Tereza, Muckova, Lubica, Prchal, Lukas, Malinak, David, Jun, Daniel, Musilek, Kamil, Worek, Franz, Nachon, Florian, Soukup, Ondrej, Korabecny, Jan
Published in Archives of toxicology (01.03.2021)
Published in Archives of toxicology (01.03.2021)
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Development of potent reversible selective inhibitors of butyrylcholinesterase as fluorescent probes
Pajk, Stane, Knez, Damijan, Košak, Urban, Zorović, Maja, Brazzolotto, Xavier, Coquelle, Nicolas, Nachon, Florian, Colletier, Jacques-Philippe, Živin, Marko, Stojan, Jure, Gobec, Stanislav
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
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Structure, activities and biomedical applications of human butyrylcholinesterase
Masson, Patrick, Carletti, Eugénie, Nachon, Florian
Published in Protein and peptide letters (01.10.2009)
Published in Protein and peptide letters (01.10.2009)
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