Baseline physiological data from anesthetized pigs in a VX intoxication model
Goulay, R., Fémy, F., Nervo, A., Valentino, S., Madi, M., Joly, A.-L., Servonnet, A., Nachon, F., Reymond, C., Jaffré, N.
Published in Toxicology letters (01.06.2024)
Published in Toxicology letters (01.06.2024)
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Pressure-induced molten globule state of human acetylcholinesterase: structural and dynamical changes monitored by neutron scattering
Marion, J, Trovaslet, M, Martinez, N, Masson, P, Schweins, R, Nachon, F, Trapp, M, Peters, J
Published in Physical chemistry chemical physics : PCCP (07.02.2015)
Published in Physical chemistry chemical physics : PCCP (07.02.2015)
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Toxicokinetics of plasmatic VX in a swine model: comparison of a simple enzymatic titration method with a mass spectrometry method
Fémy, F., Meesemaecker, G., Belverge, N., Courageux, C., Nervo, A., Goulay, R., Reymond, C., Chantegreil, F., Madi, M., Nachon, F., Taudon, N., Jaffré, N.
Published in Archives of toxicology (01.02.2023)
Published in Archives of toxicology (01.02.2023)
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Correlation of the dynamics of native human acetylcholinesterase and its inhibited huperzine A counterpart from sub-picoseconds to nanoseconds
Trapp, M., Tehei, M., Trovaslet, M., Nachon, F., Martinez, N., Koza, M. M., Weik, M., Masson, P., Peters, J.
Published in Journal of the Royal Society interface (06.08.2014)
Published in Journal of the Royal Society interface (06.08.2014)
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(33) Structural data on the aging of diethylphosphoryl-butyrylcholinesterase
Nachon, F., Asojo, O.A., Borgstahl, G., Masson, P., Lockridge, O.
Published in Chemico-biological interactions (15.12.2005)
Published in Chemico-biological interactions (15.12.2005)
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Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents
Santoni, Gianluca, de Sousa, Julien, de la Mora, Eugenio, Dias, José, Jean, Ludovic, Sussman, Joel L, Silman, Israel, Renard, Pierre-Yves, Brown, Richard C. D, Weik, Martin, Baati, Rachid, Nachon, Florian
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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Unveiling the Full Dynamical and Reactivity Profiles of Acetylcholinesterase: A Comprehensive All-Atom Investigation
Célerse, Frédéric, Lagardère, Louis, Bouchibti, Yasmine, Nachon, Florian, Verdier, Laurent, Piquemal, Jean-Philip, Derat, Etienne
Published in ACS catalysis (02.02.2024)
Published in ACS catalysis (02.02.2024)
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Journal Article
Pressure-induced molten globule state of human acetylcholinesterase: structural and dynamical changes monitored by neutron scatteringElectronic supplementary information (ESI) available. See DOI: 10.1039/c4cp02992e
Marion, J, Trovaslet, M, Martinez, N, Masson, P, Schweins, R, Nachon, F, Trapp, M, Peters, J
Year of Publication 21.01.2015
Year of Publication 21.01.2015
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Journal Article
Role of Water in Aging of Human Butyrylcholinesterase Inhibited by Echothiophate: The Crystal Structure Suggests Two Alternative Mechanisms of Aging
Nachon, Florian, Asojo, Oluwatoyin A, Borgstahl, Gloria E. O, Masson, Patrick, Lockridge, Oksana
Published in Biochemistry (Easton) (01.02.2005)
Published in Biochemistry (Easton) (01.02.2005)
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Journal Article
Conformational Flexibility in the Peripheral Site of Torpedo californica Acetylcholinesterase Revealed by the Complex Structure with a Bifunctional Inhibitor
COLLETIER, Jacques Ph, SANSON, Benoît, NACHON, Florian, GABELLIERI, Emanuele, FATTORUSSO, Caterina, CAMPIANI, Giuseppe, WEIK, Martin
Published in Journal of the American Chemical Society (12.04.2006)
Published in Journal of the American Chemical Society (12.04.2006)
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Journal Article
Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases
Torrent, Joan, Vilchez-Acosta, Alba, Muñoz-Torrero, Diego, Trovaslet, Marie, Nachon, Florian, Chatonnet, Arnaud, Grznarova, Katarina, Acquatella-Tran Van Ba, Isabelle, Le Goffic, Ronan, Herzog, Laetitia, Béringue, Vincent, Rezaei, Human
Published in Acta neuropathologica communications (03.04.2015)
Published in Acta neuropathologica communications (03.04.2015)
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Journal Article
The Reactant State for Substrate-Activated Turnover of Acetylthiocholine by Butyrylcholinesterase is a Tetrahedral Intermediate
Tormos, Jose R, Wiley, Kenneth L, Seravalli, Javier, Nachon, Florian, Masson, Patrick, Nicolet, Yvain, Quinn, Daniel M
Published in Journal of the American Chemical Society (26.10.2005)
Published in Journal of the American Chemical Society (26.10.2005)
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Journal Article
Hysteresis of butyrylcholinesterase in the approach to steady-state kinetics
Masson, Patrick, Schopfer, Lawrence M., Froment, Marie-Thérèse, Debouzy, Jean-Claude, Nachon, Florian, Gillon, Emilie, Lockridge, Oksana, Hrabovska, Anna, Goldstein, Boris N.
Published in Chemico-biological interactions (15.12.2005)
Published in Chemico-biological interactions (15.12.2005)
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Journal Article
Photoreversible Inhibition of Cholinesterases: Catalytic Serine-Labeled Caged Butyrylcholinesterase
Loudwig, Sandra, Nicolet, Yvain, Masson, Patrick, Fontecilla-Camps, Juan C, Bon, Suzanne, Nachon, Florian, Goeldner, Maurice
Published in Chembiochem : a European journal of chemical biology (04.08.2003)
Published in Chembiochem : a European journal of chemical biology (04.08.2003)
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Journal Article
Engineering of a monomeric and low-glycosylated form of human butyrylcholinesterase: expression, purification, characterization and crystallization
Nachon, Florian, Nicolet, Yvain, Viguié, Nathalie, Masson, Patrick, Fontecilla-Camps, Juan C, Lockridge, Oksana
Published in European journal of biochemistry (01.01.2002)
Published in European journal of biochemistry (01.01.2002)
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Journal Article
Enzyme optimization, mutagenesis and directed evolution
Poyot, T, Nachon, F, Rochu, D, Fournier, D, Masson, P
Published in Annales pharmaceutiques françaises (01.03.2007)
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Published in Annales pharmaceutiques françaises (01.03.2007)
Journal Article
Trp82 and Tyr332 Are Involved in Two Quaternary Ammonium Binding Domains of Human Butyrylcholinesterase as Revealed by Photoaffinity Labeling with [3H]DDF
Nachon, Florian, Ehret-Sabatier, Laurence, Loew, Damarys, Colas, Christophe, van Dorsselaer, Alain, Goeldner, Maurice
Published in Biochemistry (Easton) (21.07.1998)
Published in Biochemistry (Easton) (21.07.1998)
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