Arylsulfonamidothiazoles as a New Class of Potential Antidiabetic Drugs. Discovery of Potent and Selective Inhibitors of the 11β-Hydroxysteroid Dehydrogenase Type 1
Barf, Tjeerd, Vallgårda, Jerk, Emond, Rikard, Häggström, Charlotta, Kurz, Guido, Nygren, Alf, Larwood, Vivienne, Mosialou, Erifili, Axelsson, Kent, Olsson, Rolf, Engblom, Lars, Edling, Naimie, Rönquist-Nii, Yuko, Öhman, Birgitta, Alberts, Peteris, Abrahmsén, Lars
Published in Journal of medicinal chemistry (29.08.2002)
Published in Journal of medicinal chemistry (29.08.2002)
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Synthesis and biological activity of a novel class of pyridazine analogues as non-competitive reversible inhibitors of protein tyrosine phosphatase 1B (PTP1B)
Liljebris, Charlotta, Martinsson, Jessica, Tedenborg, Lars, Williams, Meredith, Barker, Emma, Duffy, James E.S., Nygren, Alf, James, Stephen
Published in Bioorganic & medicinal chemistry (01.10.2002)
Published in Bioorganic & medicinal chemistry (01.10.2002)
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Journal Article
Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs. Discovery of potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1
Barf, Tjeerd, Vallgårda, Jerk, Emond, Rikard, Häggström, Charlotta, Kurz, Guido, Nygren, Alf, Larwood, Vivienne, Mosialou, Erifili, Axelsson, Kent, Olsson, Rolf, Engblom, Lars, Edling, Naimie, Rönquist-Nii, Yuko, Ohman, Birgitta, Alberts, Peteris, Abrahmsén, Lars
Published in Journal of medicinal chemistry (29.08.2002)
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Published in Journal of medicinal chemistry (29.08.2002)
Journal Article
(2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE AND SALTS THEREOF
CERNERUD MAGNUS, LUNDSTROM HELENA, LOFSTROM CLAES, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, NYLEN EMMA, NYGREN ALF
Year of Publication 06.11.2014
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Year of Publication 06.11.2014
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Pharmaceutical composition containing (2R)-methyl-1-3-[2-(3-pyridinyloxy)ethoxy]-2-pyrazinylpiperazine L-malate for treatment of serotonin-related diseases
CERNERUD MAGNUS, LUNDSTROM HELENA, LOFSTROM CLAES, ANDERSSON EMMA, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, NYGREN ALF
Year of Publication 16.09.2014
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Year of Publication 16.09.2014
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NOVEL PROCESS
LUNDSTROEM HELENA, CERNERUD MAGNUS, LOFSTROM CLAES, ANDERSSON EMMA, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, NYGREN ALF
Year of Publication 07.11.2013
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Year of Publication 07.11.2013
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(2R)-1-(3-Chloro-2-Pyrazinyl)-2-Methylpiperazine And Salts Thereof
CERNERUD MAGNUS, LUNDSTROM HELENA, LOFSTROM CLAES, ANDERSSON EMMA, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, NYGREN ALF
Year of Publication 20.06.2013
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Year of Publication 20.06.2013
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NOVEL PROCESS
LUNDSTROEM HELENA, CERNERUD MAGNUS, LOFSTROM CLAES, ANDERSSON EMMA, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, NYGREN ALF
Year of Publication 13.06.2013
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Year of Publication 13.06.2013
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(2R)-1-(3-chloro-2-pyrazinyl)-2-methylpiperazine and salts thereof
LOEFSTROEM CLAES, LUNDSTROEM HELENA, CERNERUD MAGNUS, ANDERSSON EMMA, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, NYGREN ALF
Year of Publication 02.04.2013
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Year of Publication 02.04.2013
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PROCESS FOR THE PREPARATION OF 2-METHYL PIPERAZINE DERIVATIVES
PAPTCHIKHINE, ALEXANDER, ANDERSSON, EMMA, NYGREN, ALF, FLECK, TOM, PELCMAN, MARGIT, LOFSTROM, CLAES, CERNERUD, MAGNUS, LUNDSTROM, HELENA
Year of Publication 06.03.2012
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Year of Publication 06.03.2012
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Malate salt of (2R)-methyl-1-{3-[2-(3-pyridinyloxy)ethoxy]-2-pyrazinyl}piperazine
LOEFSTROEM CLAES, LUNDSTROEM HELENA, CERNERUD MAGNUS, ANDERSSON EMMA, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, NYGREN ALF
Year of Publication 04.10.2011
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Year of Publication 04.10.2011
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Phosphoric acid addition salt of (2R)-1-[3-(2-{[2-(2-dimethylaminoethoxy)-3-pyridinyl]oxy}-ethoxy)-2-pyrazinyl]-2-methylpiperazine
Fleck, Tom, Cernerud, Magnus, Lundström, Helena, Löfström, Claes, Pelcman, Margit, Paptchikhine, Alexander, Andersson, Emma, Nygren, Alf
Year of Publication 26.10.2010
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Year of Publication 26.10.2010
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Phosphoric acid addition salt of (2R)-1-[3-(2-{[2-(2-dimethylaminoethoxy)-3-pyridinyl]oxy}-ethoxy)-2-pyrazinyl]-2-methylpiperazine
LOEFSTROEM CLAES, LUNDSTROEM HELENA, CERNERUD MAGNUS, ANDERSSON EMMA, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, NYGREN ALF
Year of Publication 26.10.2010
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Year of Publication 26.10.2010
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(2R)-1-(3-CHLORO-2-PYRAZINYL)-2-METHYLPIPERAZINE AND SALTS THEREOF
LOEFSTROEM CLAES, LUNDSTROEM HELENA, CERNERUD MAGNUS, ANDERSSON EMMA, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, FLECK BRUCE, NYGREN ALF
Year of Publication 12.01.2012
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Year of Publication 12.01.2012
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SUCCINATE SALT OF (2R)-METHYL-1-PIPERAZINE
LOEFSTROEM CLAES, LUNDSTROEM HELENA, CERNERUD MAGNUS, ANDERSSON EMMA, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, FLECK BRUCE, NYGREN ALF
Year of Publication 05.01.2012
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Year of Publication 05.01.2012
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THERAPEUTIC COMPOUND
LUNDSTROEM HELENA, CERNERUD MAGNUS, LOFSTROM CLAES, ANDERSSON EMMA, FLECK TOM, PELCMAN MARGIT, PAPTCHIKHINE ALEXANDER, NYGREN ALF
Year of Publication 03.06.2010
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Year of Publication 03.06.2010
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Novel process
CLAES LOFSTROM, MAGNUS CERNERUD, ALF NYGREN, ALEXANDER PAPTCHIKHINE, TOM FLECK, EMMA ANDERSSON, MARGIT PELCMAN, HELENA LUNDSTROM
Year of Publication 28.01.2010
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Year of Publication 28.01.2010
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