Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
Kato, Kazuki, Omura, Hiroki, Ishitani, Ryuichiro, Nureki, Osamu
Published in Annual review of biochemistry (20.06.2017)
Published in Annual review of biochemistry (20.06.2017)
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Journal Article
Taste transduction and channel synapses in taste buds
Taruno, Akiyuki, Nomura, Kengo, Kusakizako, Tsukasa, Ma, Zhongming, Nureki, Osamu, Foskett, J. Kevin
Published in Pflügers Archiv (01.01.2021)
Published in Pflügers Archiv (01.01.2021)
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Journal Article
Structural Basis for the Altered PAM Specificities of Engineered CRISPR-Cas9
Hirano, Seiichi, Nishimasu, Hiroshi, Ishitani, Ryuichiro, Nureki, Osamu
Published in Molecular cell (17.03.2016)
Published in Molecular cell (17.03.2016)
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Journal Article
Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1
Yamano, Takashi, Zetsche, Bernd, Ishitani, Ryuichiro, Zhang, Feng, Nishimasu, Hiroshi, Nureki, Osamu
Published in Molecular cell (17.08.2017)
Published in Molecular cell (17.08.2017)
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Journal Article
Structural insights into tetraspanin CD9 function
Umeda, Rie, Satouh, Yuhkoh, Takemoto, Mizuki, Nakada-Nakura, Yoshiko, Liu, Kehong, Yokoyama, Takeshi, Shirouzu, Mikako, Iwata, So, Nomura, Norimichi, Sato, Ken, Ikawa, Masahito, Nishizawa, Tomohiro, Nureki, Osamu
Published in Nature communications (30.03.2020)
Published in Nature communications (30.03.2020)
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Journal Article
Engineered CRISPR-Cas9 nuclease with expanded targeting space
Nishimasu, Hiroshi, Shi, Xi, Ishiguro, Soh, Gao, Linyi, Hirano, Seiichi, Okazaki, Sae, Noda, Taichi, Abudayyeh, Omar O, Gootenberg, Jonathan S, Mori, Hideto, Oura, Seiya, Holmes, Benjamin, Tanaka, Mamoru, Seki, Motoaki, Hirano, Hisato, Aburatani, Hiroyuki, Ishitani, Ryuichiro, Ikawa, Masahito, Yachie, Nozomu, Zhang, Feng, Nureki, Osamu
Published in Science (American Association for the Advancement of Science) (21.09.2018)
Published in Science (American Association for the Advancement of Science) (21.09.2018)
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Journal Article
TMC1 and TMC2 Proteins Are Pore-Forming Subunits of Mechanosensitive Ion Channels
Jia, Yanyan, Zhao, Yimeng, Kusakizako, Tsukasa, Wang, Yao, Pan, Chengfang, Zhang, Yuwei, Nureki, Osamu, Hattori, Motoyuki, Yan, Zhiqiang
Published in Neuron (Cambridge, Mass.) (22.01.2020)
Published in Neuron (Cambridge, Mass.) (22.01.2020)
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Journal Article
Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1
Kato, Kazuki, Nishimasu, Hiroshi, Oikawa, Daisuke, Hirano, Seiichi, Hirano, Hisato, Kasuya, Go, Ishitani, Ryuichiro, Tokunaga, Fuminori, Nureki, Osamu
Published in Nature communications (24.10.2018)
Published in Nature communications (24.10.2018)
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Journal Article
Structure of the miniature type V-F CRISPR-Cas effector enzyme
Takeda, Satoru N., Nakagawa, Ryoya, Okazaki, Sae, Hirano, Hisato, Kobayashi, Kan, Kusakizako, Tsukasa, Nishizawa, Tomohiro, Yamashita, Keitaro, Nishimasu, Hiroshi, Nureki, Osamu
Published in Molecular cell (04.02.2021)
Published in Molecular cell (04.02.2021)
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Journal Article
Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation
Morita, Keigo, Hama, Yutaro, Izume, Tamaki, Tamura, Norito, Ueno, Toshihide, Yamashita, Yoshihiro, Sakamaki, Yuriko, Mimura, Kaito, Morishita, Hideaki, Shihoya, Wataru, Nureki, Osamu, Mano, Hiroyuki, Mizushima, Noboru
Published in The Journal of cell biology (05.11.2018)
Published in The Journal of cell biology (05.11.2018)
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Journal Article
Base editors for simultaneous introduction of C-to-T and A-to-G mutations
Sakata, Rina C., Ishiguro, Soh, Mori, Hideto, Tanaka, Mamoru, Tatsuno, Kenji, Ueda, Hiroki, Yamamoto, Shogo, Seki, Motoaki, Masuyama, Nanami, Nishida, Keiji, Nishimasu, Hiroshi, Arakawa, Kazuharu, Kondo, Akihiko, Nureki, Osamu, Tomita, Masaru, Aburatani, Hiroyuki, Yachie, Nozomu
Published in Nature biotechnology (01.07.2020)
Published in Nature biotechnology (01.07.2020)
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Journal Article
Amplification-free RNA detection with CRISPR–Cas13
Shinoda, Hajime, Taguchi, Yuya, Nakagawa, Ryoya, Makino, Asami, Okazaki, Sae, Nakano, Masahiro, Muramoto, Yukiko, Takahashi, Chiharu, Takahashi, Ikuko, Ando, Jun, Noda, Takeshi, Nureki, Osamu, Nishimasu, Hiroshi, Watanabe, Rikiya
Published in Communications biology (19.04.2021)
Published in Communications biology (19.04.2021)
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Journal Article
Crystal structures of human ETB receptor provide mechanistic insight into receptor activation and partial activation
Shihoya, Wataru, Izume, Tamaki, Inoue, Asuka, Yamashita, Keitaro, Kadji, Francois Marie Ngako, Hirata, Kunio, Aoki, Junken, Nishizawa, Tomohiro, Nureki, Osamu
Published in Nature communications (09.11.2018)
Published in Nature communications (09.11.2018)
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Journal Article
Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1
Nishimasu, Hiroshi, Yamano, Takashi, Gao, Linyi, Zhang, Feng, Ishitani, Ryuichiro, Nureki, Osamu
Published in Molecular cell (06.07.2017)
Published in Molecular cell (06.07.2017)
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Journal Article
Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein
Kobayashi, Kazuhiro, Shihoya, Wataru, Nishizawa, Tomohiro, Kadji, Francois Marie Ngako, Aoki, Junken, Inoue, Asuka, Nureki, Osamu
Published in Nature structural & molecular biology (01.03.2020)
Published in Nature structural & molecular biology (01.03.2020)
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