The expression of Rpb10, a small subunit common to RNA polymerases, is modulated by the R3H domain-containing Rbs1 protein and the Upf1 helicase
Cieśla, Małgorzata, Turowski, Tomasz W, Nowotny, Marcin, Tollervey, David, Boguta, Magdalena
Published in Nucleic acids research (02.12.2020)
Published in Nucleic acids research (02.12.2020)
Get full text
Journal Article
The RNase H-like superfamily: new members, comparative structural analysis and evolutionary classification
Majorek, Karolina A, Dunin-Horkawicz, Stanislaw, Steczkiewicz, Kamil, Muszewska, Anna, Nowotny, Marcin, Ginalski, Krzysztof, Bujnicki, Janusz M
Published in Nucleic acids research (01.04.2014)
Published in Nucleic acids research (01.04.2014)
Get full text
Journal Article
Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins
Hyjek-Składanowska, Malwina, Vickers, Timothy A, Napiórkowska, Agnieszka, Anderson, Brooke A, Tanowitz, Michael, Crooke, Stanley T, Liang, Xue-hai, Seth, Punit P, Nowotny, Marcin
Published in Journal of the American Chemical Society (22.04.2020)
Published in Journal of the American Chemical Society (22.04.2020)
Get full text
Journal Article
RuvC uses dynamic probing of the Holliday junction to achieve sequence specificity and efficient resolution
Górecka, Karolina Maria, Krepl, Miroslav, Szlachcic, Aleksandra, Poznański, Jarosław, Šponer, Jiří, Nowotny, Marcin
Published in Nature communications (10.09.2019)
Published in Nature communications (10.09.2019)
Get full text
Journal Article
Drug repurposing screen to identify inhibitors of the RNA polymerase (nsp12) and helicase (nsp13) from SARS-CoV-2 replication and transcription complex
Kuzikov, Maria, Reinshagen, Jeanette, Wycisk, Krzysztof, Corona, Angela, Esposito, Francesca, Malune, Paolo, Manelfi, Candida, Iaconis, Daniela, Beccari, Andrea, Tramontano, Enzo, Nowotny, Marcin, Windshügel, Björn, Gribbon, Philip, Zaliani, Andrea
Published in Virus research (01.05.2024)
Published in Virus research (01.05.2024)
Get full text
Journal Article
Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation
Smietanski, Miroslaw, Werner, Maria, Purta, Elzbieta, Kaminska, Katarzyna H, Stepinski, Janusz, Darzynkiewicz, Edward, Nowotny, Marcin, Bujnicki, Janusz M
Published in Nature communications (09.01.2014)
Published in Nature communications (09.01.2014)
Get full text
Journal Article
Evolutionary History and Activity of RNase H1-Like Proteins in Arabidopsis thaliana
Kuciński, Jan, Chamera, Sebastian, Kmera, Aleksandra, Rowley, M Jordan, Fujii, Sho, Khurana, Pragya, Nowotny, Marcin, Wierzbicki, Andrzej T
Published in Plant and cell physiology (01.06.2020)
Published in Plant and cell physiology (01.06.2020)
Get full text
Journal Article
Structural analysis of mtEXO mitochondrial RNA degradosome reveals tight coupling of nuclease and helicase components
Razew, Michal, Warkocki, Zbigniew, Taube, Michal, Kolondra, Adam, Czarnocki-Cieciura, Mariusz, Nowak, Elzbieta, Labedzka-Dmoch, Karolina, Kawinska, Aleksandra, Piatkowski, Jakub, Golik, Pawel, Kozak, Maciej, Dziembowski, Andrzej, Nowotny, Marcin
Published in Nature communications (08.01.2018)
Published in Nature communications (08.01.2018)
Get full text
Journal Article
Structure of human TRPM8 channel
Palchevskyi, Sergii, Czarnocki-Cieciura, Mariusz, Vistoli, Giulio, Gervasoni, Silvia, Nowak, Elżbieta, Beccari, Andrea R, Nowotny, Marcin, Talarico, Carmine
Published in Communications biology (19.10.2023)
Published in Communications biology (19.10.2023)
Get full text
Journal Article
The Structural and Biochemical Characterization of Human RNase H2 Complex Reveals the Molecular Basis for Substrate Recognition and Aicardi-Goutières Syndrome Defects
Figiel, Małgorzata, Chon, Hyongi, Cerritelli, Susana M., Cybulska, Magdalena, Crouch, Robert J., Nowotny, Marcin
Published in The Journal of biological chemistry (25.03.2011)
Published in The Journal of biological chemistry (25.03.2011)
Get full text
Journal Article
Do Small Molecules Activate the TrkB Receptor in the Same Manner as BDNF? Limitations of Published TrkB Low Molecular Agonists and Screening for Novel TrkB Orthosteric Agonists
Pankiewicz, Piotr, Szybiński, Marcin, Kisielewska, Katarzyna, Gołębiowski, Filip, Krzemiński, Patryk, Rutkowska-Włodarczyk, Izabela, Moszczyński-Pętkowski, Rafał, Gurba-Bryśkiewicz, Lidia, Delis, Monika, Mulewski, Krzysztof, Smuga, Damian, Dominowski, Jakub, Janusz, Artur, Górka, Michał, Abramski, Krzysztof, Napiórkowska, Agnieszka, Nowotny, Marcin, Dubiel, Krzysztof, Kalita, Katarzyna, Wieczorek, Maciej, Pieczykolan, Jerzy, Matłoka, Mikołaj
Published in Pharmaceuticals (Basel, Switzerland) (21.07.2021)
Published in Pharmaceuticals (Basel, Switzerland) (21.07.2021)
Get full text
Journal Article
Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD
Nowotny, Marcin, Cerritelli, Susana M, Ghirlando, Rodolfo, Gaidamakov, Sergei A, Crouch, Robert J, Yang, Wei
Published in The EMBO journal (09.04.2008)
Published in The EMBO journal (09.04.2008)
Get full text
Journal Article
RNase H2 roles in genome integrity revealed by unlinking its activities
Chon, Hyongi, Sparks, Justin L., Rychlik, Monika, Nowotny, Marcin, Burgers, Peter M., Crouch, Robert J., Cerritelli, Susana M.
Published in Nucleic acids research (01.03.2013)
Published in Nucleic acids research (01.03.2013)
Get full text
Journal Article
Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease
Gaur, Vineet, Wyatt, Haley D.M., Komorowska, Weronika, Szczepanowski, Roman H., de Sanctis, Daniele, Gorecka, Karolina M., West, Stephen C., Nowotny, Marcin
Published in Cell reports (Cambridge) (10.03.2015)
Published in Cell reports (Cambridge) (10.03.2015)
Get full text
Journal Article