Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome
Donovan, Katherine A, An, Jian, Nowak, Radosław P, Yuan, Jingting C, Fink, Emma C, Berry, Bethany C, Ebert, Benjamin L, Fischer, Eric S
Published in eLife (01.08.2018)
Published in eLife (01.08.2018)
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Journal Article
Structure of the Human cGAS–DNA Complex Reveals Enhanced Control of Immune Surveillance
Zhou, Wen, Whiteley, Aaron T., de Oliveira Mann, Carina C., Morehouse, Benjamin R., Nowak, Radosław P., Fischer, Eric S., Gray, Nathanael S., Mekalanos, John J., Kranzusch, Philip J.
Published in Cell (12.07.2018)
Published in Cell (12.07.2018)
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A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density
Pearce, Nicholas M., Krojer, Tobias, Bradley, Anthony R., Collins, Patrick, Nowak, Radosław P., Talon, Romain, Marsden, Brian D., Kelm, Sebastian, Shi, Jiye, Deane, Charlotte M., von Delft, Frank
Published in Nature communications (24.04.2017)
Published in Nature communications (24.04.2017)
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Plasticity in binding confers selectivity in ligand-induced protein degradation
Nowak, Radosław P., DeAngelo, Stephen L., Buckley, Dennis, He, Zhixiang, Donovan, Katherine A., An, Jian, Safaee, Nozhat, Jedrychowski, Mark P., Ponthier, Charles M., Ishoey, Mette, Zhang, Tinghu, Mancias, Joseph D., Gray, Nathanael S., Bradner, James E., Fischer, Eric S.
Published in Nature chemical biology (01.07.2018)
Published in Nature chemical biology (01.07.2018)
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Journal Article
Ballistic superconductivity in semiconductor nanowires
Zhang, Hao, Gül, Önder, Conesa-Boj, Sonia, Nowak, Michał P., Wimmer, Michael, Zuo, Kun, Mourik, Vincent, de Vries, Folkert K., van Veen, Jasper, de Moor, Michiel W. A., Bommer, Jouri D. S., van Woerkom, David J., Car, Diana, Plissard, Sébastien R, Bakkers, Erik P.A.M., Quintero-Pérez, Marina, Cassidy, Maja C., Koelling, Sebastian, Goswami, Srijit, Watanabe, Kenji, Taniguchi, Takashi, Kouwenhoven, Leo P.
Published in Nature communications (06.07.2017)
Published in Nature communications (06.07.2017)
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Journal Article
Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15
Faust, Tyler B., Yoon, Hojong, Nowak, Radosław P., Donovan, Katherine A., Li, Zhengnian, Cai, Quan, Eleuteri, Nicholas A., Zhang, Tinghu, Gray, Nathanael S., Fischer, Eric S.
Published in Nature chemical biology (01.01.2020)
Published in Nature chemical biology (01.01.2020)
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Journal Article
Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML
Brand, Matthias, Jiang, Baishan, Bauer, Sophie, Donovan, Katherine A, Liang, Yanke, Wang, Eric S, Nowak, Radosław P, Yuan, Jingting C, Zhang, Tinghu, Kwiatkowski, Nicholas, Müller, André C, Fischer, Eric S, Gray, Nathanael S, Winter, Georg E
Published in Cell chemical biology (21.02.2019)
Published in Cell chemical biology (21.02.2019)
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Journal Article
Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations
de Wispelaere, Mélissanne, Du, Guangyan, Donovan, Katherine A., Zhang, Tinghu, Eleuteri, Nicholas A., Yuan, Jingting C., Kalabathula, Joann, Nowak, Radosław P., Fischer, Eric S., Gray, Nathanael S., Yang, Priscilla L.
Published in Nature communications (01.08.2019)
Published in Nature communications (01.08.2019)
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Journal Article
Small-molecule-induced polymerization triggers degradation of BCL6
Słabicki, Mikołaj, Yoon, Hojong, Koeppel, Jonas, Nitsch, Lena, Roy Burman, Shourya S., Di Genua, Cristina, Donovan, Katherine A., Sperling, Adam S., Hunkeler, Moritz, Tsai, Jonathan M., Sharma, Rohan, Guirguis, Andrew, Zou, Charles, Chudasama, Priya, Gasser, Jessica A., Miller, Peter G., Scholl, Claudia, Fröhling, Stefan, Nowak, Radosław P., Fischer, Eric S., Ebert, Benjamin L.
Published in Nature (London) (03.12.2020)
Published in Nature (London) (03.12.2020)
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Journal Article
Bruton tyrosine kinase degradation as a therapeutic strategy for cancer
Dobrovolsky, Dennis, Wang, Eric S., Morrow, Sara, Leahy, Catharine, Faust, Tyler, Nowak, Radosław P., Donovan, Katherine A., Yang, Guang, Li, Zhengnian, Fischer, Eric S., Treon, Steven P., Weinstock, David M., Gray, Nathanael S.
Published in Blood (28.02.2019)
Published in Blood (28.02.2019)
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Chemo-proteomics exploration of HDAC degradability by small molecule degraders
Xiong, Yuan, Donovan, Katherine A., Eleuteri, Nicholas A., Kirmani, Nadia, Yue, Hong, Razov, Anthony, Krupnick, Noah M., Nowak, Radosław P., Fischer, Eric S.
Published in Cell chemical biology (21.10.2021)
Published in Cell chemical biology (21.10.2021)
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Journal Article
Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK)
Powell, Chelsea E, Gao, Yang, Tan, Li, Donovan, Katherine A, Nowak, Radosław P, Loehr, Amanda, Bahcall, Magda, Fischer, Eric S, Jänne, Pasi A, George, Rani E, Gray, Nathanael S
Published in Journal of medicinal chemistry (10.05.2018)
Published in Journal of medicinal chemistry (10.05.2018)
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Targeted protein degradation: from mechanisms to clinic
Tsai, Jonathan M., Nowak, Radosław P., Ebert, Benjamin L., Fischer, Eric S.
Published in Nature reviews. Molecular cell biology (01.09.2024)
Published in Nature reviews. Molecular cell biology (01.09.2024)
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Journal Article
Shadow-wall lithography of ballistic superconductor–semiconductor quantum devices
Heedt, Sebastian, Quintero-Pérez, Marina, Borsoi, Francesco, Fursina, Alexandra, van Loo, Nick, Mazur, Grzegorz P., Nowak, Michał P., Ammerlaan, Mark, Li, Kongyi, Korneychuk, Svetlana, Shen, Jie, van de Poll, May An Y., Badawy, Ghada, Gazibegovic, Sasa, de Jong, Nick, Aseev, Pavel, van Hoogdalem, Kevin, Bakkers, Erik P. A. M., Kouwenhoven, Leo P.
Published in Nature communications (13.08.2021)
Published in Nature communications (13.08.2021)
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Journal Article
Mutant‐Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug‐Resistant Mutations
Jang, Jaebong, To, Ciric, De Clercq, Dries J. H., Park, Eunyoung, Ponthier, Charles M., Shin, Bo Hee, Mushajiang, Mierzhati, Nowak, Radosław P., Fischer, Eric S., Eck, Michael J., Jänne, Pasi A., Gray, Nathanael S.
Published in Angewandte Chemie International Edition (17.08.2020)
Published in Angewandte Chemie International Edition (17.08.2020)
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Hard Superconducting Gap in InSb Nanowires
Gül, Önder, Zhang, Hao, de Vries, Folkert K, van Veen, Jasper, Zuo, Kun, Mourik, Vincent, Conesa-Boj, Sonia, Nowak, Michał P, van Woerkom, David J, Quintero-Pérez, Marina, Cassidy, Maja C, Geresdi, Attila, Koelling, Sebastian, Car, Diana, Plissard, Sébastien R, Bakkers, Erik P. A. M, Kouwenhoven, Leo P
Published in Nano letters (12.04.2017)
Published in Nano letters (12.04.2017)
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Quantized conductance doubling and hard gap in a two-dimensional semiconductor–superconductor heterostructure
Kjaergaard, M., Nichele, F., Suominen, H. J., Nowak, M. P., Wimmer, M., Akhmerov, A. R., Folk, J. A., Flensberg, K., Shabani, J., Palmstrøm, C. J., Marcus, C. M.
Published in Nature communications (29.09.2016)
Published in Nature communications (29.09.2016)
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Structural basis of regulated m7G tRNA modification by METTL1–WDR4
Li, Jiazhi, Wang, Longfei, Hahn, Quentin, Nowak, Radosław P., Viennet, Thibault, Orellana, Esteban A., Roy Burman, Shourya S., Yue, Hong, Hunkeler, Moritz, Fontana, Pietro, Wu, Hao, Arthanari, Haribabu, Fischer, Eric S., Gregory, Richard I.
Published in Nature (London) (12.01.2023)
Published in Nature (London) (12.01.2023)
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