Akt-Mediated Phosphorylation of Argonaute 2 Downregulates Cleavage and Upregulates Translational Repression of MicroRNA Targets
Horman, Shane R., Janas, Maja M., Litterst, Claudia, Wang, Bingbing, MacRae, Ian J., Sever, Mary J., Morrissey, David V., Graves, Paul, Luo, Biao, Umesalma, Shaikamjad, Qi, Hank H., Miraglia, Loren J., Novina, Carl D., Orth, Anthony P.
Published in Molecular cell (09.05.2013)
Published in Molecular cell (09.05.2013)
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Journal Article
The lncRNA SLNCR1 Mediates Melanoma Invasion through a Conserved SRA1-like Region
Schmidt, Karyn, Joyce, Cailin E., Buquicchio, Frank, Brown, Adam, Ritz, Justin, Distel, Robert J., Yoon, Charles H., Novina, Carl D.
Published in Cell reports (Cambridge) (31.05.2016)
Published in Cell reports (Cambridge) (31.05.2016)
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Journal Article
The lncRNA SLNCR Recruits the Androgen Receptor to EGR1-Bound Genes in Melanoma and Inhibits Expression of Tumor Suppressor p21
Schmidt, Karyn, Carroll, Johanna S, Yee, Elaine, Thomas, Dolly D, Wert-Lamas, Leon, Neier, Steven C, Sheynkman, Gloria, Ritz, Justin, Novina, Carl D
Published in Cell reports (Cambridge) (21.05.2019)
Published in Cell reports (Cambridge) (21.05.2019)
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Journal Article
Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor
Schmidt, Karyn, Weidmann, Chase A., Hilimire, Thomas A., Yee, Elaine, Hatfield, Breanne M., Schneekloth, John S., Weeks, Kevin M., Novina, Carl D.
Published in Cell reports (Cambridge) (14.01.2020)
Published in Cell reports (Cambridge) (14.01.2020)
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Journal Article
Targeted DNA methylation in human cells using engineered dCas9-methyltransferases
Xiong, Tina, Meister, Glenna E., Workman, Rachael E., Kato, Nathaniel C., Spellberg, Michael J., Turker, Fulya, Timp, Winston, Ostermeier, Marc, Novina, Carl D.
Published in Scientific reports (27.07.2017)
Published in Scientific reports (27.07.2017)
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Journal Article
Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737
Del Gaizo Moore, Victoria, Brown, Jennifer R, Certo, Michael, Love, Tara M, Novina, Carl D, Letai, Anthony
Published in The Journal of clinical investigation (01.01.2007)
Published in The Journal of clinical investigation (01.01.2007)
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Journal Article
Genomic basis for the convergent evolution of electric organs
Gallant, Jason R., Traeger, Lindsay L., Volkening, Jeremy D., Moffett, Howell, Chen, Po-Hao, Novina, Carl D., Phillips, George N., Anand, Rene, Wells, Gregg B., Pinch, Matthew, Güth, Robert, Unguez, Graciela A., Albert, James S., Zakon, Harold H., Samanta, Manoj P., Sussman, Michael R.
Published in Science (American Association for the Advancement of Science) (27.06.2014)
Published in Science (American Association for the Advancement of Science) (27.06.2014)
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Journal Article
Intronic miR-211 Assumes the Tumor Suppressive Function of Its Host Gene in Melanoma
Levy, Carmit, Khaled, Mehdi, Iliopoulos, Dimitrios, Janas, Maja M., Schubert, Steffen, Pinner, Sophie, Chen, Po-Hao, Li, Shuqiang, Fletcher, Anne L., Yokoyama, Satoru, Scott, Kenneth L., Garraway, Levi A., Song, Jun S., Granter, Scott R., Turley, Shannon J., Fisher, David E., Novina, Carl D.
Published in Molecular cell (10.12.2010)
Published in Molecular cell (10.12.2010)
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Journal Article
MicroRNA-repressed mRNAs contain 40S but not 60S components
Wang, Bingbing, Yanez, Adrienne, Novina, Carl D
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (08.04.2008)
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Journal Article
Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins
Wang, Bingbing, Li, Shuqiang, Novina, Carl D, Qi, Hank H, Chowdhury, Dipanjan, Shi, Yang
Published in Nature structural & molecular biology (01.12.2009)
Published in Nature structural & molecular biology (01.12.2009)
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Journal Article
MicroRNA expression profiling identifies activated B cell status in chronic lymphocytic leukemia cells
Li, Shuqiang, Moffett, Howell F, Lu, Jun, Werner, Lillian, Zhang, Hao, Ritz, Jerome, Neuberg, Donna, Wucherpfennig, Kai W, Brown, Jennifer R, Novina, Carl D
Published in PloS one (08.03.2011)
Published in PloS one (08.03.2011)
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Journal Article
Alternative RISC assembly: binding and repression of microRNA-mRNA duplexes by human Ago proteins
Janas, Maja M, Wang, Bingbing, Harris, Abigail S, Aguiar, Mike, Shaffer, Jonathan M, Subrahmanyam, Yerramilli V B K, Behlke, Mark A, Wucherpfennig, Kai W, Gygi, Steven P, Gagnon, Etienne, Novina, Carl D
Published in RNA (Cambridge) (01.11.2012)
Published in RNA (Cambridge) (01.11.2012)
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Journal Article
Protein engineering strategies for improving the selective methylation of target CpG sites by a dCas9-directed cytosine methyltransferase in bacteria
Xiong, Tina, Rohm, Dahlia, Workman, Rachael E, Roundtree, Lauren, Novina, Carl D, Timp, Winston, Ostermeier, Marc
Published in PloS one (18.12.2018)
Published in PloS one (18.12.2018)
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Journal Article
Recapitulation of Short RNA-Directed Translational Gene Silencing In Vitro
Wang, Bingbing, Love, Tara M., Call, Matthew E., Doench, John G., Novina, Carl D.
Published in Molecular cell (19.05.2006)
Published in Molecular cell (19.05.2006)
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Journal Article
Feed-forward microprocessing and splicing activities at a microRNA-containing intron
Janas, Maja M, Khaled, Mehdi, Schubert, Steffen, Bernstein, Jacob G, Golan, David, Veguilla, Rosa A, Fisher, David E, Shomron, Noam, Levy, Carmit, Novina, Carl D
Published in PLoS genetics (01.10.2011)
Published in PLoS genetics (01.10.2011)
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Journal Article
Lentivirus-delivered stable gene silencing by RNAi in primary cells
Stewart, Sheila A, Dykxhoorn, Derek M, Palliser, Deborah, Mizuno, Hana, Yu, Evan Y, An, Dong Sung, Sabatini, David M, Chen, Irvin S Y, Hahn, William C, Sharp, Phillip A, Weinberg, Robert A, Novina, Carl D
Published in RNA (Cambridge) (01.04.2003)
Published in RNA (Cambridge) (01.04.2003)
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Journal Article
siRNA-directed inhibition of HIV-1 infection
Shankar, Premlata, Sharp, Phillip A, Novina, Carl D, Murray, Michael F, Dykxhoorn, Derek M, Beresford, Paul J, Riess, Jonathan, Lee, Sang-Kyung, Collman, Ronald G, Lieberman, Judy
Published in Nature medicine (01.07.2002)
Published in Nature medicine (01.07.2002)
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Journal Article
microRNA expression in the biology, prognosis, and therapy of Waldenström macroglobulinemia
Roccaro, Aldo M., Sacco, Antonio, Chen, Changzhong, Runnels, Judith, Leleu, Xavier, Azab, Feda, Azab, Abdel Kareem, Jia, Xiaoying, Ngo, Hai T., Melhem, Molly R., Burwick, Nicholas, Varticovski, Lyuba, Novina, Carl D., Rollins, Barrett J., Anderson, Kenneth C., Ghobrial, Irene M.
Published in Blood (30.04.2009)
Published in Blood (30.04.2009)
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Journal Article
Reduced Expression of Ribosomal Proteins Relieves MicroRNA-Mediated Repression
Janas, Maja M., Wang, Eric, Love, Tara, Harris, Abigail S., Stevenson, Kristen, Semmelmann, Karlheinz, Shaffer, Jonathan M., Chen, Po-Hao, Doench, John G., Yerramilli, Subrahmanyam V.B.K., Neuberg, Donna S., Iliopoulos, Dimitrios, Housman, David E., Burge, Christopher B., Novina, Carl D.
Published in Molecular cell (27.04.2012)
Published in Molecular cell (27.04.2012)
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