Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial
Aung, Kyaw L, Fischer, Sandra E, Denroche, Robert E, Jang, Gun-Ho, Dodd, Anna, Creighton, Sean, Southwood, Bernadette, Liang, Sheng-Ben, Chadwick, Dianne, Zhang, Amy, O'Kane, Grainne M, Albaba, Hamzeh, Moura, Shari, Grant, Robert C, Miller, Jessica K, Mbabaali, Faridah, Pasternack, Danielle, Lungu, Ilinca M, Bartlett, John M S, Ghai, Sangeet, Lemire, Mathieu, Holter, Spring, Connor, Ashton A, Moffitt, Richard A, Yeh, Jen Jen, Timms, Lee, Krzyzanowski, Paul M, Dhani, Neesha, Hedley, David, Notta, Faiyaz, Wilson, Julie M, Moore, Malcolm J, Gallinger, Steven, Knox, Jennifer J
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Published in Clinical cancer research (15.03.2018)
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Published in Science (American Association for the Advancement of Science) (08.07.2011)
Published in Science (American Association for the Advancement of Science) (08.07.2011)
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Published in Molecular cancer research (01.01.2017)
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Published in Cell (28.10.2021)
Published in Cell (28.10.2021)
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Notta, Faiyaz, Zandi, Sasan, Takayama, Naoya, Dobson, Stephanie, Gan, Olga I., Wilson, Gavin, Kaufmann, Kerstin B., McLeod, Jessica, Laurenti, Elisa, Dunant, Cyrille F., McPherson, John D., Stein, Lincoln D., Dror, Yigal, Dick, John E.
Published in Science (American Association for the Advancement of Science) (08.01.2016)
Published in Science (American Association for the Advancement of Science) (08.01.2016)
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GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer
O'Kane, Grainne M, Grünwald, Barbara T, Jang, Gun-Ho, Masoomian, Mehdi, Picardo, Sarah, Grant, Robert C, Denroche, Robert E, Zhang, Amy, Wang, Yifan, Lam, Bernard, Krzyzanowski, Paul M, Lungu, Illinca M, Bartlett, John M S, Peralta, Melanie, Vyas, Foram, Khokha, Rama, Biagi, James, Chadwick, Dianne, Ramotar, Stephanie, Hutchinson, Shawn, Dodd, Anna, Wilson, Julie M, Notta, Faiyaz, Zogopoulos, George, Gallinger, Steven, Knox, Jennifer J, Fischer, Sandra E
Published in Clinical cancer research (15.09.2020)
Published in Clinical cancer research (15.09.2020)
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Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer
Kreso, Antonija, O'Brien, Catherine A., van Galen, Peter, Gan, Olga I., Notta, Faiyaz, Brown, Andrew M. K., Ng, Karen, Ma, Jing, Wienholds, Erno, Dunant, Cyrille, Pollett, Aaron, Gallinger, Steven, McPherson, John, Mullighan, Charles G., Shibata, Darryl, Dick, John E.
Published in Science (American Association for the Advancement of Science) (01.02.2013)
Published in Science (American Association for the Advancement of Science) (01.02.2013)
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Ordered and deterministic cancer genome evolution after p53 loss
Baslan, Timour, Morris, John P., Zhao, Zhen, Reyes, Jose, Ho, Yu-Jui, Tsanov, Kaloyan M., Bermeo, Jonathan, Tian, Sha, Zhang, Sean, Askan, Gokce, Yavas, Aslihan, Lecomte, Nicolas, Erakky, Amanda, Varghese, Anna M., Zhang, Amy, Kendall, Jude, Ghiban, Elena, Chorbadjiev, Lubomir, Wu, Jie, Dimitrova, Nevenka, Chadalavada, Kalyani, Nanjangud, Gouri J., Bandlamudi, Chaitanya, Gong, Yixiao, Donoghue, Mark T. A., Socci, Nicholas D., Krasnitz, Alex, Notta, Faiyaz, Leach, Steve D., Iacobuzio-Donahue, Christine A., Lowe, Scott W.
Published in Nature (London) (25.08.2022)
Published in Nature (London) (25.08.2022)
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The value of GATA6 immunohistochemistry and computer-assisted diagnosis to predict clinical outcome in advanced pancreatic cancer
Duan, Kai, Jang, Gun-Ho, Grant, Robert C., Wilson, Julie M., Notta, Faiyaz, O’Kane, Grainne M., Knox, Jennifer J., Gallinger, Steven, Fischer, Sandra
Published in Scientific reports (22.07.2021)
Published in Scientific reports (22.07.2021)
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Genomic Features and Classification of Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma
Golan, Talia, O’Kane, Grainne M., Denroche, Robert E., Raitses-Gurevich, Maria, Grant, Robert C., Holter, Spring, Wang, Yifan, Zhang, Amy, Jang, Gun Ho, Stossel, Chani, Atias, Dikla, Halperin, Sharon, Berger, Raanan, Glick, Yulia, Park, J. Patrick, Cuggia, Adeline, Williamson, Laura, Wong, Hui-Li, Schaeffer, David F., Renouf, Daniel J., Borgida, Ayelet, Dodd, Anna, Wilson, Julie M., Fischer, Sandra E., Notta, Faiyaz, Knox, Jennifer J., Zogopoulos, George, Gallinger, Steven
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
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Published in Cancer discovery (01.10.2020)
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A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal
Milyavsky, Michael, Gan, Olga I., Trottier, Magan, Komosa, Martin, Tabach, Ofer, Notta, Faiyaz, Lechman, Eric, Hermans, Karin G., Eppert, Kolja, Konovalova, Zhanna, Ornatsky, Olga, Domany, Eytan, Meyn, M. Stephen, Dick, John E.
Published in Cell stem cell (06.08.2010)
Published in Cell stem cell (06.08.2010)
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Maddipati, Ravikanth, Norgard, Robert J, Baslan, Timour, Rathi, Komal S, Zhang, Amy, Saeid, Asal, Higashihara, Taku, Wu, Feng, Kumar, Angad, Annamalai, Valli, Bhattacharya, Saurav, Raman, Pichai, Adkisson, Christian A, Pitarresi, Jason R, Wengyn, Maximilian D, Yamazoe, Taiji, Li, Jinyang, Balli, David, LaRiviere, Michael J, Ngo, Tuong-Vi C, Folkert, Ian W, Millstein, Ian D, Bermeo, Jonathan, Carpenter, Erica L, McAuliffe, John C, Oktay, Maja H, Brekken, Rolf A, Lowe, Scott W, Iacobuzio-Donahue, Christine A, Notta, Faiyaz, Stanger, Ben Z
Published in Cancer discovery (01.02.2022)
Published in Cancer discovery (01.02.2022)
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Martinez, Sebastien, Wu, Shifei, Geuenich, Michael, Malik, Ahmad, Weber, Ramona, Woo, Tristan, Zhang, Amy, Jang, Gun Ho, Dervovic, Dzana, Al-Zahrani, Khalid N., Tsai, Ricky, Fodil, Nassima, Gros, Philippe, Gallinger, Steven, Neely, G. Gregory, Notta, Faiyaz, Sendoel, Ataman, Campbell, Kieran, Elling, Ulrich, Schramek, Daniel
Published in Nature communications (20.06.2024)
Published in Nature communications (20.06.2024)
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PTHrP Drives Pancreatic Cancer Growth and Metastasis and Reveals a New Therapeutic Vulnerability
Pitarresi, Jason R, Norgard, Robert J, Chiarella, Anna M, Suzuki, Kensuke, Bakir, Basil, Sahu, Varun, Li, Jinyang, Zhao, Jun, Marchand, Benoît, Wengyn, Maximilian D, Hsieh, Antony, Kim, Il-Kyu, Zhang, Amy, Sellin, Karine, Lee, Vivian, Takano, Shigetsugu, Miyahara, Yoji, Ohtsuka, Masayuki, Maitra, Anirban, Notta, Faiyaz, Kremer, Richard, Stanger, Ben Z, Rustgi, Anil K
Published in Cancer discovery (01.07.2021)
Published in Cancer discovery (01.07.2021)
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Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma
Topham, James T., Tsang, Erica S., Karasinska, Joanna M., Metcalfe, Andrew, Ali, Hassan, Kalloger, Steve E., Csizmok, Veronika, Williamson, Laura M., Titmuss, Emma, Nielsen, Karina, Negri, Gian Luca, Spencer Miko, Sandra E., Jang, Gun Ho, Denroche, Robert E., Wong, Hui-li, O’Kane, Grainne M., Moore, Richard A., Mungall, Andrew J., Loree, Jonathan M., Notta, Faiyaz, Wilson, Julie M., Bathe, Oliver F., Tang, Patricia A., Goodwin, Rachel, Morin, Gregg B., Knox, Jennifer J., Gallinger, Steven, Laskin, Janessa, Marra, Marco A., Jones, Steven J. M., Schaeffer, David F., Renouf, Daniel J.
Published in Nature communications (08.10.2022)
Published in Nature communications (08.10.2022)
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Kossenkov, Andrew V, Milcarek, Andrew, Notta, Faiyaz, Jang, Gun-Ho, Wilson, Julie M, Gallinger, Steven, Zhou, Daniel Cui, Ding, Li, Ghosh, Jagadish C, Perego, Michela, Morotti, Annamaria, Locatelli, Marco, Robert, Marie E, Vaira, Valentina, Altieri, Dario C
Published in PloS one (12.10.2022)
Published in PloS one (12.10.2022)
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