Orally available selective melanocortin-4 receptor antagonists stimulate food intake and reduce cancer-induced cachexia in mice
Weyermann, Philipp, Dallmann, Robert, Magyar, Josef, Anklin, Corinne, Hufschmid, Martina, Dubach-Powell, Judith, Courdier-Fruh, Isabelle, Henneböhle, Marco, Nordhoff, Sonja, Mondadori, Cesare
Published in PloS one (19.03.2009)
Published in PloS one (19.03.2009)
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Journal Article
A Novel Biosynthetic Pathway Providing Precursors for Fatty Acid Biosynthesis and Secondary Metabolite Formation in Myxobacteria
Mahmud, Taifo, Bode, Helge Bjo¨rn, Silakowski, Barbara, Kroppenstedt, Reiner M., Xu, Mingjie, Nordhoff, Sonja, Ho¨fle, Gerhard, Mu¨ller, Rolf
Published in The Journal of biological chemistry (06.09.2002)
Published in The Journal of biological chemistry (06.09.2002)
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Journal Article
Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors
Alen, Jo, Schade, Markus, Wagener, Markus, Christian, Frank, Nordhoff, Sonja, Merla, Beatrix, Dunkern, Torsten R, Bahrenberg, Gregor, Ratcliffe, Paul
Published in Journal of medicinal chemistry (11.07.2019)
Published in Journal of medicinal chemistry (11.07.2019)
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Journal Article
Inhibiting the immunoproteasome's β5i catalytic activity affects human peripheral blood‐derived immune cell viability
Pletinckx, Katrien, Vaßen, Silke, Schlusche, Ilka, Nordhoff, Sonja, Bahrenberg, Gregor, Dunkern, Torsten R.
Published in Pharmacology research & perspectives (01.08.2019)
Published in Pharmacology research & perspectives (01.08.2019)
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Journal Article
In silico fragment-based discovery of DPP-IV S1 pocket binders
Rummey, Christian, Nordhoff, Sonja, Thiemann, Meinolf, Metz, Günther
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Journal Article
PYRAZOLYL-BASED CARBOXAMIDES II AS CRAC CHANNEL INHIBITORS
KLESS ACHIM, VOSS FELIX, RITTER STEFANIE, WACHTEN SEBASTIAN, NORDHOFF SONJA
Year of Publication 11.09.2015
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Year of Publication 11.09.2015
Patent
PYRAZOLYL-BASED CARBOXAMIDES I AS CRAC CHANNEL INHIBITORS
KLESS ACHIM, VOSS FELIX, RITTER STEFANIE, WACHTEN SEBASTIAN, NORDHOFF SONJA
Year of Publication 11.09.2015
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Year of Publication 11.09.2015
Patent
The design of potent and selective inhibitors of DPP-4: Optimization of ADME properties by amide replacements
Nordhoff, Sonja, Bulat, Stephan, Cerezo-Gálvez, Silvia, Hill, Oliver, Hoffmann-Enger, Barbara, López-Canet, Meritxell, Rosenbaum, Claudia, Rummey, Christian, Thiemann, Meinolf, Matassa, Victor G., Edwards, Paul J., Feurer, Achim
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
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Journal Article
Discovery of β-homophenylalanine based pyrrolidin-2-ylmethyl amides and sulfonamides as highly potent and selective inhibitors of dipeptidyl peptidase IV
Nordhoff, Sonja, Cerezo-Gálvez, Silvia, Deppe, Holger, Hill, Oliver, López-Canet, Meritxell, Rummey, Christian, Thiemann, Meinolf, Matassa, Victor G., Edwards, Paul J., Feurer, Achim
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
Published in Bioorganic & medicinal chemistry letters (01.08.2009)
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Journal Article
From lead to preclinical candidate: Optimization of β-homophenylalanine based inhibitors of dipeptidyl peptidase IV
Nordhoff, Sonja, López-Canet, Meritxell, Hoffmann-Enger, Barbara, Bulat, Stephan, Cerezo-Gálvez, Silvia, Hill, Oliver, Rosenbaum, Claudia, Rummey, Christian, Thiemann, Meinolf, Matassa, Victor G., Edwards, Paul J., Feurer, Achim
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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Journal Article
The reversed binding of β-phenethylamine inhibitors of DPP-IV: X-ray structures and properties of novel fragment and elaborated inhibitors
Nordhoff, Sonja, Cerezo-Gálvez, Silvia, Feurer, Achim, Hill, Oliver, Matassa, Victor G., Metz, Günther, Rummey, Christian, Thiemann, Meinolf, Edwards, Paul J.
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
Published in Bioorganic & medicinal chemistry letters (15.03.2006)
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Journal Article
6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL
RIDER, David, DUNKERN, Torsten, WAGENER, Markus, NORDHOFF, Sonja, BAHRENBERG, Gregor, JAKOB, Florian
Year of Publication 31.07.2019
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Year of Publication 31.07.2019
Patent
6-membered cyclic amines or lactames substituted with urea and phenyl
Nordhoff, Sonja, Wagener, Markus, Rider, David, Jakob, Florian, Bahrenberg, Gregor, Dunkern, Torsten
Year of Publication 16.05.2019
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Year of Publication 16.05.2019
Patent
6-membered cyclic amines or lactames substituted with urea and phenyl
Nordhoff, Sonja, Wagener, Markus, Rider, David, Jakob, Florian, Bahrenberg, Gregor, Dunkern, Torsten
Year of Publication 23.04.2019
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Year of Publication 23.04.2019
Patent
PYRAZOLYL-BASED CARBOXAMIDES II AS CRAC CHANNEL INHIBITORS
KLESS, Achim, WACHTEN, Sebastian, RITTER, Stefanie, VOSS, Felix, NORDHOFF, Sonja
Year of Publication 25.01.2017
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Year of Publication 25.01.2017
Patent
6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL
RIDER, David, DUNKERN, Torsten, WAGENER, Markus, NORDHOFF, Sonja, BAHRENBERG, Gregor, JAKOB, Florian
Year of Publication 29.03.2018
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Year of Publication 29.03.2018
Patent
6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL
RIDER, DAVID, JAKOB, FLORIAN, WAGENER, MARKUS, BAHRENBERG, GREGOR, NORDHOFF, SONJA, DUNKERN, TORSTEN
Year of Publication 29.03.2018
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Year of Publication 29.03.2018
Patent
6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL
RIDER DAVID, JAKOB FLORIAN, WAGENER MARKUS, NORDHOFF SONJA, BAHRENBERG GREGOR, DUNKERN TORSTEN
Year of Publication 22.03.2018
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Year of Publication 22.03.2018
Patent
PYRAZOLYL-BASED CARBOXAMIDES AS CRAC INHIBITORS
VOSS, FELIX, OBERBÖRSCH, STEFAN, RITTER, STEFANIE, NORDHOFF, SONJA, WACHTEN, SEBASTIAN
Year of Publication 30.12.2015
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Year of Publication 30.12.2015
Patent