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Molla, A, Korneyeva, M, Gao, Q, Vasavanonda, S, Schipper, P J, Mo, H M, Markowitz, M, Chernyavskiy, T, Niu, P, Lyons, N, Hsu, A, Granneman, G R, Ho, D D, Boucher, C A, Leonard, J M, Norbeck, D W, Kempf, D J
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Published in Nature medicine (01.07.1996)
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X-ray crystallographic structure of ABT-378 (lopinavir) bound to HIV-1 protease
STOLL, Vincent, WENYING QIN, KEMPF, Dale, SHAM, Hing L, NORBECK, Daniel W, STEWART, Kent D, JAKOB, Clarissa, CHANG PARK, WALTER, K, SIMMER, R. L, HELFRICH, Rosalind, BUSSIERE, Dirk, KAO, J
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Published in Bioorganic & medicinal chemistry (01.08.2002)
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Novel α- and β-Amino Acid Inhibitors of Influenza Virus Neuraminidase
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ABT-378, a Highly Potent Inhibitor of the Human Immunodeficiency Virus Protease
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Published in Antimicrobial Agents and Chemotherapy (01.12.1998)
Published in Antimicrobial Agents and Chemotherapy (01.12.1998)
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Human Serum Attenuates the Activity of Protease Inhibitors toward Wild-Type and Mutant Human Immunodeficiency Virus
Molla, Akhteruzzaman, Vasavanonda, Sudthida, Kumar, Gondi, Sham, Hing L., Johnson, Marianne, Grabowski, Brian, Denissen, Jon F., Kohlbrenner, William, Plattner, Jacob J., Leonard, John M., Norbeck, Daniel W., Kempf, Dale J.
Published in Virology (New York, N.Y.) (25.10.1998)
Published in Virology (New York, N.Y.) (25.10.1998)
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In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants with Increased Resistance to ABT-378, a Novel Protease Inhibitor
Carrillo, A, Stewart, K D, Sham, H L, Norbeck, D W, Kohlbrenner, W E, Leonard, J M, Kempf, D J, Molla, A
Published in Journal of Virology (01.09.1998)
Published in Journal of Virology (01.09.1998)
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Discovery of Ritonavir, a Potent Inhibitor of HIV Protease with High Oral Bioavailability and Clinical Efficacy
Kempf, Dale J, Sham, Hing L, Marsh, Kennan C, Flentge, Charles A, Betebenner, David, Green, Brian E, McDonald, Edith, Vasavanonda, Sudthida, Saldivar, Ayda, Wideburg, Norman E, Kati, Warren M, Ruiz, Lisa, Zhao, Chen, Fino, LynnMarie, Patterson, Jean, Molla, Akhteruzzaman, Plattner, Jacob J, Norbeck, Daniel W
Published in Journal of medicinal chemistry (12.02.1998)
Published in Journal of medicinal chemistry (12.02.1998)
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Novel lopinavir analogues incorporating non-Aromatic P-1 side chains—Synthesis and structure–Activity relationships
Sham, Hing L, Zhao, Chen, Li, Leping, Betebenner, David A, Saldivar, Ayda, Vasavanonda, Sudthida, Kempf, Dale J, Plattner, Jacob J, Norbeck, Daniel W
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
Published in Bioorganic & medicinal chemistry letters (04.11.2002)
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Synthesis and activity of N-acyl azacyclic urea HIV-1 protease inhibitors with high potency against multiple drug resistant viral strains
Zhao, Chen, Sham, Hing L., Sun, Minghua, Stoll, Vincent S., Stewart, Kent D., Lin, Shuqun, Mo, Hongmei, Vasavanonda, Sudthida, Saldivar, Ayda, Park, Chang, McDonald, Edith J., Marsh, Kennan C., Klein, Larry L., Kempf, Dale J., Norbeck, Daniel W.
Published in Bioorganic & medicinal chemistry letters (15.12.2005)
Published in Bioorganic & medicinal chemistry letters (15.12.2005)
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Convergent synthesis of polyether ionophore antibiotics: an approach to the synthesis of the monensin tetrahydropyran-bis(tetrahydrofuran) via the ester enolate Claisen rearrangement and reductive decarboxylation
Ireland, Robert E, Norbeck, Daniel W, Mandel, Gretchen S, Mandel, Neil S
Published in Journal of the American Chemical Society (01.05.1985)
Published in Journal of the American Chemical Society (01.05.1985)
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Novel lopinavir analogues incorporating heterocyclic replacements of six-member cyclic urea––synthesis and structure–activity relationships
Sham, Hing L., Betebenner, David A., Rosenbrook, William, Herrin, Thomas, Saldivar, Ayda, Vasavanonda, Sudthida, Plattner, Jacob J., Norbeck, Daniel W.
Published in Bioorganic & medicinal chemistry letters (17.05.2004)
Published in Bioorganic & medicinal chemistry letters (17.05.2004)
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Synthesis and SAR studies of potent HIV protease inhibitors containing novel dimethylphenoxyl acetates as P2 ligands
XIAOQI CHEN, KEMPF, Dale J, LIN LI, SHAM, Hing L, VASAVANONDA, Sudthida, WIDEBURG, Norman E, SALDIVAR, Ayda, MARSH, Kennan C, MCDONALD, Edith, NORBECK, Daniel W
Published in Bioorganic & medicinal chemistry letters (03.11.2003)
Published in Bioorganic & medicinal chemistry letters (03.11.2003)
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Genotypic Changes in Human Immunodeficiency Virus Type 1 Associated with Loss of Suppression of Plasma Viral RNA Levels in Subjects Treated with Ritonavir (Norvir) Monotherapy
Eastman, P S, Mittler, J, Kelso, R, Gee, C, Boyer, E, Kolberg, J, Urdea, M, Leonard, J M, Norbeck, D W, Mo, H, Markowitz, M
Published in Journal of Virology (01.06.1998)
Published in Journal of Virology (01.06.1998)
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Synthesis and SAR studies of potent HIV protease inhibitors containing novel dimethylphenoxyl acetates as P 2 ligands
Chen, Xiaoqi, Kempf, Dale J., Li, Lin, Sham, Hing L., Vasavanonda, Sudthida, Wideburg, Norman E., Saldivar, Ayda, Marsh, Kennan C., McDonald, Edith, Norbeck, Daniel W.
Published in Bioorganic & medicinal chemistry letters (01.11.2003)
Published in Bioorganic & medicinal chemistry letters (01.11.2003)
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Influence of stereochemistry on activity and binding modes for C2 symmetry-based diol inhibitors of HIV-1 protease
Hosur, Madhusoodan V, Bhat, T. Narayana, Kempf, Dale J, Baldwin, Eric T, Liu, Beishan, Gulnik, Sergei, Wideburg, Norman E, Norbeck, Daniel W, Appelt, Krzysztof, Erickson, John W
Published in Journal of the American Chemical Society (01.02.1994)
Published in Journal of the American Chemical Society (01.02.1994)
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Synthesis and structure-activity relationships of a novel series of HIV-1 protease inhibitors encompassing ABT-378 (Lopinavir)
SHAM, Hing L, BETEBENNER, David A, XIAOQI CHEN, SALDIVAR, Ayda, VASAVANONDA, Sudthida, KEMPF, Dale J, PLATTNER, Jacob J, NORBECK, Daniel W
Published in Bioorganic & medicinal chemistry letters (22.04.2002)
Published in Bioorganic & medicinal chemistry letters (22.04.2002)
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A Novel, Picomolar Inhibitor of Human Immunodeficiency Virus Type 1 Protease
Sham, Hing L, Zhao, Chen, Stewart, Kent D, Betebenner, David A, Lin, Shuqun, Park, Chang H, Kong, Xiang-P, Rosenbrook, William, Herrin, Thomas, Madigan, Darold, Vasavanonda, Suthida, Lyons, Nicholas, Molla, Akhter, Saldivar, Ayda, Marsh, Kennan C, McDonald, Edith, Wideburg, Norman E, Denissen, Jon F, Robins, Terrel, Kempf, Dale J, Plattner, Jacob J, Norbeck, Daniel W
Published in Journal of medicinal chemistry (19.01.1996)
Published in Journal of medicinal chemistry (19.01.1996)
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